Health care system

This thesis contributes to a better understanding of the relationship between residential energy efficiency and health. The thesis argues that residential energy efficiency improvements are complex interventions in complex socio‐technical systems.

765p runthenight04 02-02-2023 15 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An analysis of Liberia’s 2007 national health policy: lessons for health systems strengthening and chronic disease care in poor, post-conflict countries

14p panasonic03 16-12-2011 49 3   Download

Dissemination is the purposive distribution of information and intervention materials to a specific public health or clinical practice audience. The intent is to spread information and the associated evidence-based interventions. Research on dissemination addresses how information about health promotion and care interventions is created, packaged,

4p toshiba23 11-12-2011 52 3   Download

Tailoring an intervention to the context and system redesign related to the intervention: A case study of implementing shared medical appointments for diabetes Susan R Kirsh*1,2, Renée H Lawrence1 and David C Aron1,2 Address: 1Center for Quality Improvement Research, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA and 2School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA Email: Susan R Kirsh* - susan.kirsh@va.gov; Renée H Lawrence - renee.lawrence2@va.gov; David C Aron - david.aron@va.gov * Corresponding author...

15p toshiba23 11-12-2011 73 3   Download

Address: 1South Central Mental Illness Research, Education, and Clinical Center (SC-MIRECC), Central Arkansas Veterans Healthcare System, North Little Rock, USA, 2Central Arkansas Veterans Healthcare System, HSR&D, Center for Mental Healthcare and Outcomes Research (CeMHOR), North Little Rock, USA, 3University of Arkansas for Medical Sciences, Department of Psychiatry, Division of Health Services Research, Little Rock, USA, 4Michael E.

7p toshiba23 11-12-2011 63 6   Download

Cheryl B Stetler*1, Lynn McQueen2, John Demakis3 and Brian S Mittman4 Address: 1Independent Consultant, Amherst, Massachusetts, USA, 2Office of Quality and Performance, U.S. Department of Veterans Affairs, Washington DC, USA, 3(Retired) Health Services Research and Development Service, U.S. Department of Veterans Affairs, Washington, DC, USA and 4VA Center for the Study of Healthcare Provider Behavior, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA Email: Cheryl B Stetler* - Cheryl.Stetler@comcast.net; Lynn McQueen - Lynn.McQueen@va.

11p toshiba23 11-12-2011 70 4   Download

Anne Sales*1, Christian Helfrich2, P Michael Ho3,4, Ashley Hedeen2, Mary E Plomondon3,4, Yu-Fang Li2, Alison Connors1 and John S Rumsfeld3,4 Address: 1University of Alberta, Edmonton, Alberta, Canada, 2VA Puget Sound Health Care System, Seattle, Washington, USA, 3VA Eastern Colorado Health Care System, Denver, Colorado, USA and 4University of Denver Health Sciences Center, Denver, Colorado, USA Email: Anne Sales* - anne.sales@ualberta.ca; Christian Helfrich - christian.helfrich@va.gov; P Michael Ho - michael.ho@va.gov; Ashley Hedeen - ashley.hedeen@va.gov; Mary E Plomondon - meg.

12p toshiba23 11-12-2011 60 2   Download

Address: 1Veterans Affairs (VA) Health Services Research and Development (HSR&D) Center of Excellence for the Study of Healthcare Provider Behaviour, VA Greater Los Angeles Healthcare System, Sepulveda, CA, USA and 2Department of Health Services, UCLA School of Public Health, Los Angeles, CA, USA Email: Elizabeth M Yano - elizabeth.yano@va.gov

15p toshiba23 11-12-2011 41 2   Download

Candice C Bowman*1, Elisa J Sobo2, Steven M Asch3, Allen L Gifford4 for the HIV/Hepatitis Quality Enhancement Research Initiative Address: 1Health Services Research & Development, VA San Diego Healthcare System, San Diego, California, USA, 2Department of Anthropology, San Diego State University, San Diego, California, USA, 3Center for the Study of Healthcare Provider Behavior, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA and 4Center for Health Quality, Outcomes, and Economic Research, VA New England Healthcare System, Bedford, Massachusetts, USA Email: Candice C B...

13p toshiba23 11-12-2011 41 2   Download

Carolyn M Wallace*† and Marcia W Legro† Address: Health Services Research & Development, VA Puget Sound Health Care System, Seattle, Washington, USA Email: Carolyn M Wallace* - Carolyn.Wallace1@va.gov; Marcia W Legro - mwlegro@msn.com * Corresponding author †Equal contributors Published: 22 April 2008 Implementation Science 2008, 3:22 doi:10.1186/1748-5908-3-22 Received: 18 August 2006 Accepted: 22 April 2008

8p toshiba23 11-12-2011 63 2   Download

’Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: To take care of the patients’: Qualitative analysis of Veterans Health Administration personnel experiences with a clinical informatics system

8p toshiba22 22-11-2011 54 4   Download

Ovarian cancer is the leading cause of death among women with gynecologic malignancies in the United States. Advanced ovarian cancers are difficult to cure with the current available chemotherapy, which has many associated systemic side effects. Doxorubicin is one such chemotherapeutic agent that can cause cardiotoxicity. Novel methods of delivering chemotherapy without significant side effects are therefore of critical need.

12p toshiba23 18-11-2011 54 4   Download

The cationic peptide antibiotic polymyxin has recently been reevaluated in the treatment of severe infections caused by gram negative bacteria. Methods: In this study, the genetic determinants for capsular polysaccharide level and lipopolysaccharide modification involved in polymyxin B resistance of the opportunistic pathogen Klebsiella pneumoniae were characterized. The expressional control of the genes responsible for the resistance was assessed by a LacZ reporter system.

16p toshiba23 18-11-2011 48 1   Download

Sindbis virus (SV) is the prototype of alphaviruses which are a group of widely distributed human and animal pathogens. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an RNA-binding protein that shuttles between the nucleus and the cytoplasm. Our recent studies found that hnRNP A1 relocates from nucleus to cytoplasm in Sindbis virus (SV)-infected cells. hnRNP A1 binds to the 5′ UTR of SV RNA and facilitates the viral RNA replication and translation.

7p toshiba23 18-11-2011 68 4   Download

The treatment of AIDS remains a serious challenge owing to high genetic variation of Human Immunodeficiency Virus type 1 (HIV-1). The use of different antiretroviral drugs (ARV) is significantly limited by severe side-effects that further compromise the quality of life of the AIDS patient. In the present study, we have evaluated a liposome system for the delivery of nevirapine, a hydrophobic non-nucleoside reverse transcriptase inhibitor. Liposomes were prepared from egg phospholipids using thin film hydration.

9p toshiba23 18-11-2011 45 3   Download

Abstract Intercellular signaling by cytokines is a vital feature of the innate immune system. In skin, an inflammatory response is mediated by cytokines and an entwined network of cellular communication between T-cells and epidermal keratinocytes. Dysregulated cytokine production, orchestrated by activated T-cells homing to the skin, is believed to be the main cause of psoriasis, a common inflammatory skin disorder.

19p toshiba23 18-11-2011 52 2   Download

RNA interference (RNAi) is a powerful tool to silence gene expression post-transcriptionally. Delivering sequences of RNAi in vivo remains a problem. The aim of this study was to use JC virus (JCV) virus-like particles (VLPs) as a vector for delivering RNAi in silencing the cytokine gene of IL-10. Methods: JCV VLPs were generated by recombinant JCV VP1 protein in yeast expression system. DNA fragment containing IL-10 shRNA was packaged into VLPs by osmotic shock. Results: In RAW 264.7 cells, IL-10 shRNA was found to reduce IL-10 expression by 85 to 89%, as compared with VLPs alone.

9p toshiba23 18-11-2011 52 2   Download

As the origin of a life-and-death signal detected from systemic arterial pressure, which sequentially increases (pro-life) and decreases (pro-death) to reflect progressive dysfunction of central cardiovascular regulation during the advancement towards brain stem death in critically ill patients, the rostral ventrolateral medulla (RVLM) is a suitable neural substrate for mechanistic delineation of this fatal phenomenon.

9p toshiba23 18-11-2011 46 2   Download

Abstract Although gait change is considered a useful indicator of severity in animal models of Parkinson's disease, systematic and extensive gait analysis in animal models of neurological deficits is not well established. The CatWalk-assisted automated gait analysis system provides a comprehensive way to assess a number of dynamic and static gait parameters simultaneously. In this study, we used the Catwalk system to investigate changes in gait parameters in adult rats with unilateral 6-OHDA-induced lesions and the...

10p toshiba23 18-11-2011 53 7   Download

Abstract Glucose homeostasis in humans is an important factor for the functioning of nervous system. Hypoglycemia and hyperglycemia is found to be associated with central and peripheral nerve system dysfunction. Changes in acetylcholine receptors have been implicated in the pathophysiology of many major diseases of the central nervous system (CNS). In the present study we showed the effects of insulin induced hypoglycemia and streptozotocin induced diabetes on the cerebellar cholinergic receptors, GLUT3 and muscle cholinergic activity. Results showed enhanced binding parameters and gene...

9p toshiba23 18-11-2011 54 2   Download