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Hepatoprotective effect
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The methanol extracts as well as some compounds from this plant exhibited anti-inflammatory, antimicrobial activity, antioxidant, hepatoprotective and anti-cancer effect, and antiosteoporotic. On going to search for bioactive components from the Vietnamese plant, this paper reported the isolation of seven phenolic compounds including one new from the aerial parts of A. ilicifolius. The cytotoxic activity of the isolates against two cancer cell lines (HepG2 and SK-LU1) were also screened and reported herein.
5p
dianmotminh02
03-05-2024
6
1
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Hypericum sampsonii or Sampson’s St John’s Wort is a species of flowering plant in the Hypericaceae family. Our previous study revealed the diverse and bioactive chemical constituents of the plant. This study investigates the antioxidant activity and potential hepatoprotective of Hypericum sampsonii extract (BLD1 extract) in vitro and in vivo.
7p
vilarry
12-03-2024
8
1
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The present experiment is aimed to evaluate the hepatoprotective effects of purslane (PuE) and fig leaves (FlE) extracts on diclofenac-sodium (DS) induced hepatotoxicity in rats. Adult male rats were pretreated orally with PuE and FlE extracts at a dose of 10ml/kg and 200mg/kg body weight, respectively for 14 days. Co-treatment of DS 16mg/kg body weight was given orally for 7days.
7p
viisac
23-09-2023
2
1
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The main problem now is how to lead people to consume mbuja which nevertheless contains bioactive molecules, which can help in the treatment or in the prevention of some chronic diseases. In order to the valorisation of its nutraceutic property, a study on effect of mbuja oil consumption compare to palm olein and corn oils on renal and liver dysfunction factors in Rats was carried out.
7p
viisac
23-09-2023
5
1
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The genus Phyllanthus contains over 600 species distributed throughout the tropical and subtropical regions of the world. The plants of genus Phyllanthus have long been used to treat liver diseases
14p
vidudley
20-02-2023
4
2
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(BQ) Ebook Pueraria: The genus Pueraria - Part 2 presents the following content: Human studies of kudzu as a treatment for alcohol abuse; Chemopreventive effects of isoflavones on estrogen-dependent diseases: osteoporosis and cancer of the breast, prostate and endometrium; Chemistry and hepatoprotective effect of Pueraria saponins; Mammalian metabolism of Pueraria isoflavonoids; Synthesis of naturally occurring isoflavones and their analogs...
128p
runordie7
30-08-2022
5
3
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Hepatopathies are an important group of disorders in dogs where proper nutritional care is crucial. Supplementation with a hepatoprotectant like silybin can improve liver function and should not interfere with nutrient digestibility. The purpose of this study was to investigate the effect of both pure silybin and commercial hepatoprotectant on nutrients digestibility, liver function indices and health status in healthy dogs (EXP1).
14p
vidarwin
23-02-2022
10
1
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The results indicated that both PPP and WP exhibited antioxidant activity. Also, rats fed on diets supplemented with 10% PPP, 10% WP or 10% of their mixture (PPWP) for 28 days showed a potential hepatoprotective effects compared to liver injury control group (IC).
6p
schindler
30-12-2021
11
0
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The present research work was carried out to study the nephro and hepatoprotective effect of Ocimum sanctum in broilers exposed to high doses of gentamicin, which is common in poultry practice of Tamilnadu.
6p
chauchaungayxua11
23-03-2021
7
1
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The effect of fresh juice extract of Azadirachta indica on lipid profile and hepatic function of Plasmodium berghei infected albino mice were investigated. Thirty adult male mice were placed in five groups of six mice each, acclimatized for 7 days and used for the study. Group A was normal control and had free access to feed and water while groups B to E were infected with Plasmodium berghei, and confirmed of parasitamia on the third day. Groups C, D and E were further given standard anti malaria drug (5 mg/kg body weight of Artesunate), 4.3ml/kg and 8.
9p
caygaocaolon8
07-11-2020
10
1
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In addition, Stevia rebaudiana Bertoni has recently been shown to have antioxidant and anti-inflammatory properties. Mint (Mentha avensis L.) is a common medicinal herb. The mixture consisting of the aqueous extract of Ganoderma lucidum (Curtis) P. Karst, mint and stevia powder had a high antioxidant activity, in free radical scavenging method (DPPH), reaching 85.7% at concentration 1000 µg/mL and valuable IC50 was 559.7 µg/mL.
7p
tomhiddleston
25-05-2020
26
0
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The current study investigated hepatoprotective and antioxidant effects of Aegle marmelos leaves extract. The major constituent present in the extract i.e. rutin was quantifed by using HPLC. Further, the study explored hepatoprotective efect of A. marmelos (70% ethanol extract) in combination with piperine.
13p
vijiraiya2711
27-05-2020
14
1
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Turmeric is a popular herbal dietary supplement that has been considered safe and even shown to have hepatoprotective properties. In the recent times, however, there have been a few case reports of turmeric-induced liver injury. We report a 55-year-old woman with chronic turmeric consumption whose initial diagnosis was acute autoimmune hepatitis. She declined steroid treatment, and hence, we recommended discontinuing her long-term turmeric usage. A month after discontinuation, her liver function returned to normal.
4p
covid19
11-05-2020
17
1
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The present study was conducted to evaluate the hepatoprotective effect of the Hydroethanolic extract of the stem bark Oroxylum indicum against CCl4 induced hepatotoxicity. The hydroethanolic extract was prepared. Albino Wistar rats were taken for the study. The extract was prepared at a dose rate of 100mg/kg body weight, 300mg/kg body weight, 900mg/kg body weight. Carbon tetrachloride was used to induce hepatotoxicity.
7p
caygaocaolon4
01-04-2020
18
1
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Liver ischemia reperfusion (I/R) damage which is frequently seen in clinical hepatobiliary surgeries has no effective treatment for it. Liv-52, known to have hepatoprotective effects, is a natural antioxidant drug licensed by the Ministry of Health of India.
9p
vimax2711
27-03-2020
11
1
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The role of ethanolic extract of Andrographis paniculata (AP), in preventing cisplatin (CP) induced oxidative damage in rat liver was studied. The study included 60 Wistar albino rats were divided into 12 rats in each group. Group I served as normal control group. To group II rats, CP was administered at 7.5mg/kg body weight intraperitoneally for single dose. Rats in group III were administered AP at the dose of 500mg/kg body weight for 45 days. Group IV rats were pre-treated with AP 15 days prior to CP administration and followed by AP treatment for 45 days.
10p
chauchaungayxua4
18-03-2020
16
2
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Andrographis paniculata, commonly known as Kalmegh, is used both in Ayurvedic and Unani system of medicines because of its immunological, antibacterial and hepatoprotective properties. It is an annual herb has high value compound used in the treatment of the various diseases. A field experiment was conducted at the research farm of RAK College of Agriculture, Sehore (Madhya Pradesh) during Kharif 2015 & 2016.
6p
chauchaungayxua4
18-03-2020
9
1
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Paracetamol induced hepatotoxicity is a common model for accessing the hepatoprotective nature of new molecules. This study was conducted to evaluate the potential of aqueous extract of Gyrocarpus asiaticus on paracetamol induced hepatotoxicity in zebra fish. Fish were challenged with 20mM concentration of paracetamol followed by treatment with aqueous extract of Gyrocarpus asiaticus. Serum was evaluated for alanine transferase (ALT) concentration and liver samples were collected for histopathological analysis.
6p
quenchua2
15-12-2019
17
0
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The in vitro total antioxidant and anti-inflammatory capacity of the methanol extract of Ixora duffii leaf (―Trang to‖ in Vietnamese) was investigated using the phosphomolypdenum method and the bovine serum albumin denaturation test, respectively. The results showed that the methanol extract of I. duffii leaf possessed relatively high antioxidant activity (OD0,5 = 15.551 ± 0.344 μg/mL) compared to that of the standard, trolox (OD0,5=2.315 ± 0.083 μg/mL). The antiinflammatory effect using bovine serum albumin denaturation test showed that the activity of the methanol extract of I.
12p
gaunguyen6789
22-10-2019
26
2
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Malva sylvestris is traditionally used for the treatment of liver diseases, but sufficient pharmacological-based scientific literature is not available online to authenticate its use in liver ailments. We aimed to assess the hepatoprotective effects of Malva sylvestris against paracetamol-induced hepatotoxicity in mice.
7p
sony2711
01-02-2019
12
1
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