Improved variants

The thesis studied the development and implementation of the conceptual Continuous Improvement Teamworking (CIT) Model for strategic performance improvement in retail banking operations. The investigation using of a dominant qualitative to a Less-dominant quantitative approach as a mixed-method strategy revealed the importance of the CIT Model realised through the CTIO (Concern-Task-Interaction-Outcome) Problem-Solving Cycle. The CTIO Cycle is a variant form of the traditional Deming-Shewhart PDCA (Plan-Do-Check-Action) Cycle.

311p runthenight04 02-02-2023 6 2   Download

Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with only traditional risk factors is still not clear. Hence, our primary aim was to summarize literature on risk prediction models including genetic variants for CRC, while our secondary aim was to evaluate the improvement of discriminatory accuracy when adding SNPs to a prediction model with only traditional risk factors.

21p vielonmusk 21-01-2022 14 1   Download

Precision medicine promises to improve both the efficacy and safety of therapeutic products by better informing why some patients respond well to a drug, and some experience adverse reactions, while others do not. Pharmacogenomics is a key component of precision medicine and can be utilized to select optimal doses for patients, more precisely identify individuals who will respond to a treatment and avoid serious drug-related toxicities.

5p caothientrangnguyen 09-05-2020 11 2   Download

The result showed that two product spaces were highly similar. However, compared to IPM-QDA, IPM-RDA better improved the discriminability, increased the consensus among the assessors and reduced the variability of ideal profile. These findings indicated that ranking was more efficient than rating in gathering descriptive data using naïve consumers.

7p quilen 30-11-2019 22 1   Download

The reader may wonder why the amplifier stages studied in previous chapters are not suited to high-power applications. Suppose we wish to deliver 1 W to an 8- speaker. Approximating the signal with a sinusoid of peak amplitude VP, we express the power absorbed by the speaker as:

82p vanmanh1008 23-05-2013 47 6   Download

Feedback is an integral part of our lives. Try touching your fingertips with your eyes closed; you may not succeed the first time because you have broken a feedback loop that ordinarily “regulates” your motions. The regulatory role of feedback manifests itself in biological, mechanical, and electronic systems, allowing precise realization of “functions.” For example, an amplifier targeting a precise gain of 2.00 is designed much more easily with feedback than without.

16p vanmanh1008 23-05-2013 38 3   Download

The need for operating circuits at increasingly higher speeds has always challenged designers. From radar and television systems in the 1940s to gigahertz microprocessors today, the demand for pushing circuits to higher frequencies has required a solid understanding of their speed limitations. In this chapter, we study the effects that limit the speed of transistors and circuits, identifying topologies that better lend themselves to high-frequency operation.

25p vanmanh1008 23-05-2013 64 3   Download

In two cycles of an error-prone PCR process, variants of formate dehy-drogenase from Candida boidiniiwere created which revealed an up to 4.4-fold (440%) higher residual activity after entrapment in polyacrylamide gels than the wild-type enzyme. These were identified in an assay using sin-gle precursor molecules of polyacrylamide instead of the complete gel for selection.

8p inspiron33 25-03-2013 44 5   Download

l-Asparaginase (EC 3.5.1.1,l-ASNase) catalyses the hydrolysis ofl-Asn, producingl-Asp and ammonia. This enzyme is an anti-neoplastic agent; it is used extensively in the chemotherapy of acute lymphoblastic leukaemia. In this study, we describe the use of in vitro directed evolution to create a new enzyme variant with improved thermal stability.

12p vinaphone15 27-02-2013 52 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Locus Reference Genomic sequences: an improved basis for describing human DNA variants

7p panasonic02 15-12-2011 42 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Improved variant discovery through local re-alignment of short-read next-generation sequencing data using SRMA...

12p thulanh22 20-11-2011 42 4   Download