Metabolism

Bệnh gan nhiễm mỡ liên quan chuyển hóa (Metabolic associated fatty liver disease - MAFLD) là nguyên nhân hàng đầu gây bệnh gan mạn tính, trong dân số thừa cân, béo phì chiếm 50,7%. Nghiên cứu này nhằm tìm ra tỷ lệ hiện mắc và đặc điểm lâm sàng ở bệnh nhân thừa cân, béo phì mắc bệnh gan nhiễm mỡ liên quan chuyển hóa góp phần quản lý toàn diện nhóm bệnh nhân này.

8p vipanly 28-10-2024 0 0   Download

In patients with end-stage chronic kidney failure, there are a number of disorders that cause bone damage. In particular, secondary hyperparathyroidism (SHPT) is related to chronic kidney failure, a calcium-phosphorus metabolism disorder that causes bone disorder.

6p viengfa 23-10-2024 1 0   Download

Starch metabolism is known to be an important pathway in the growth and development of plants. This study was conducted to investigate the genome-wide identification and structural analysis of genes encoding uridine diphosphate glucose pyrophosphorylase (UGPase), a key enzyme in starch synthesis in cassava, and to analyze the expression profiles of these genes based on publicly available RNA-seq data.

6p vibecca 01-10-2024 0 0   Download

This study aims to survey the clinical and paraclinical characteristics and coronary artery lesions in metabolic syndrome patients with coronary artery disease at Ninh Thuan General Hospital; and evaluate the relationship and correlation between the characteristics and extent of coronary artery lesions and the components of metabolic syndrome.

9p viormkorn 27-09-2024 2 1   Download

This study aimed to compare the efficacy of dapagliflozin and empagliflozin as add-on therapies for type 2 diabetes mellitus (T2DM) over 6 months in a real-world setting, focusing on key metabolic parameters.

8p viormkorn 27-09-2024 3 1   Download

This study aims to investigate the clinical and paraclinical characteristics of Obstructive Sleep Apnea Syndrome in patients with Metabolic Syndrome and to examine the correlation between the Apnea-Hypopnea Index (AHI) and lipid profile indices, blood sugar, waist circumference, blood pressure, and body mass index (BMI).

7p viormkorn 27-09-2024 1 1   Download

We report a case of a 7-year-old child with urolithiasis in autotransplanted kidney treated with minipercutaneous nephrolithotomy. The patient presented with hematuria and graft hydronephrosis. Diagnostic procedures revealed ureterolithiasis as a cause of obstruction and blood in urine. Mini-percutaneous nephrolithotomy was successfully performed and during surgery, all stone fragments were removed.

5p vinatisu 29-08-2024 2 1   Download

Wilson’s disease (WD) is a rare inherited copper metabolism disorder with many clinical symptoms highlighted by hepatic and cerebral features. We present the case of a 17 - year - old female patient with generalized tonic - clonic seizures and cerebellar ataxia who presented to our hospital.

4p vinatisu 29-08-2024 2 1   Download

Polycystic ovary syndrome is the most common endocrine disorder in women of reproductive age. Insulin resistance appears to be a critical factor in PCOS pathogenesis. Metformin, an insulin-sensitizing agent, is thus the preferred treatment option for PCOS.

8p vinatisu 29-08-2024 3 1   Download

Glutamine synthetase (EC 6.3.1.2) is an enzyme which assimilates ammonium into amino acids. Therefore, GS plays an essential role in the metabolism of nitrogen. In vascular plants, GS is devided into two groups: cytosol - located isoform (GS1) and plastid – located isoform (GS2). Surveys have shown that GS1 gene was used widely to generate transgenic plants. Effects on the growth characteristics of GS1 transgenic plants have been reported in many researches.

7p vilarry 01-04-2024 8 2   Download

The biological importance and varied metabolic capabilities of specific microbial strains have long been established in the scientific community. Strains have, in the past, been largely defined and characterized based on microbial isolates.

16p vibransone 28-03-2024 7 1   Download

Bài viết trình bày việc tìm hiểu mối liên quan giữa nồng độ gamma-glutamyl transferase (GGT) huyết tương với hội chứng chuyển hóa (Metabolic syndrome - MS) tại Bệnh viện Trung ương Quân đội 108.

7p vishekhar 01-11-2023 8 1   Download

Bài viết Tiếp cận chẩn đoán bệnh gan nhiễm mỡ liên quan chuyển hóa (Metabolic associatedfatty liver disease - MAFLD) nêu rõ hơn những lợi ích khi tiếp cận chẩn đoán theo hướng bệnh gan nhiễm mỡ liên quan chuyển hóa.

10p vihawkeye 26-05-2023 13 5   Download

Bệnh gan nhiễm mỡ liên quan chuyển hóa (Metabolic Associated Fatty Liver Disease - MAFLD) là định nghĩa mới được đề xuất bởi hội đồng chuyên gia quốc tế năm 2021 để thay thế cho thuật ngữ bệnh gan nhiễm mỡ không do rượu (Nonalcoholic fatty liver disease - NAFLD) và đã được Hiệp hội nghiên cứu về gan Châu Á - Thái Bình Dương đưa vào hướng dẫn chẩn đoán và điều trị.

14p vihawkeye 26-05-2023 14 3   Download

The objectives of the present study are: To design and produce functional samples of woven single-layer, fire-resistant fabrics made from natural, FR man-made cellulosics, and high-performance synthetic blended yarns; to determine the physiological consequences and health risks associated with wearing PPC in hot, humid environments in relation to metabolic heat production and physical work for firefighters trying to maintain the balance between protection and comfort, and its implication on the required Station Wear fabric properties.

184p runordie3 06-07-2022 9 3   Download

Early life exposure to adverse environments affects cardiovascular and metabolic systems in the offspring. These programmed effects are transmissible to a second generation through both male and female lines, suggesting germline transmission. We have previously shown that prenatal overexposure to the synthetic glucocorticoid dexamethasone (Dex) in rats reduces birth weight in the first generation (F1), a phenotype which is transmitted to a second generation (F2), particularly through the male line.

15p vimichaelfaraday 25-03-2022 15 1   Download

Oncogenic metabolic reprogramming contributes to tumor growth and immune evasion. The intertumoral metabolic heterogeneity and interaction of distinct metabolic pathways may determine patient outcomes. In this study, we aim to determine the clinical and immunological significance of metabolic subtypes according to the expression levels of genes related to glycolysis and cholesterol-synthesis in bladder cancer (BCa).

15p vielonmusk 21-01-2022 17 0   Download

Lactic acid produced by tumors has been shown to overcome immune surveillance, by suppressing the activation and function of T cells in the tumor microenvironment. The strategies employed to impair tumor cell glycolysis could improve immunosurveillance and tumor growth regulation. Dichloroacetate (DCA) limits the tumorderived lactic acid by altering the cancer cell metabolism.

12p vielonmusk 21-01-2022 7 0   Download

Peroxisomes are pivotal metabolic organelles that exist in almost all eukaryote cells. A reduction in numbers and enzymatic activities of peroxisomes was found in colon adenocarcinomas. However, the role of peroxisomes or the peroxisome pathway in colorectal cancer (CRC) is not defined.

17p vielonmusk 21-01-2022 12 0   Download

Administration of poly (ADP-ribose) polymerase (PARP) inhibitors after achieving a response to platinum-containing drugs significantly prolonged relapse-free survival compared to placebo administration. PARP inhibitors have been used in clinical practice. However, patients with platinum-resistant relapsed ovarian cancer still have a poor prognosis and there is an unmet need.

11p vielonmusk 21-01-2022 10 1   Download