Mitochondrial functions

In this study, we investigated the therapeutic potential of bacteriostatic antibiotics in regulating the growth potential of colorectal cancer (CRC) cells, which differ in their metastatic potential and mitochondrial functions.

18p vikoch 27-06-2024 2 1   Download

Ebook "Mitochondrial DNA: Methods and protocols" is to provide procedures for research scientists and clinicians to analyze mitochondrial DNA and the proteins involved in its maintenance. A review of mitochondrial function, genetics, and diseases is presented in the first chapter by Douglas Wallace. Mitochondrial DNA: Methods and Protocols is organized into two main parts, the first addressing protocols to analyze the DNA.

419p dongmelo 27-05-2024 6 2   Download

Ebook "Folding for the synapse" addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex.

315p tracanhphuonghoa1007 22-04-2024 3 2   Download

Ebook "Sperm chromatin: Biological and clinical applications in male infertility and assisted reproduction" covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome.

515p tracanhphuonghoa1007 22-04-2024 3 2   Download

Ebook "Mitochondrial oxidative phosphorylation: Nuclear-encoded genes, enzyme regulation, and pathophysiology" focuses on new developments in mitochondrial morphology, biogenesis, and evolution, as well as in structure and regulatory functions of the enzyme complexes of OxPhos by experts in their fi elds. Particular emphasis is given to the oxygen consuming enzyme of the respiratory chain, cytochrome c oxidase, representing a controlling step of OxPhos.

378p tracanhphuonghoa1007 22-04-2024 3 2   Download

The mitochondrial genome is transcribed as continuous polycistrons of RNA containing multiple genes. As a consequence, post-transcriptional events are critical for the regulation of gene expression and therefore all aspects of mitochondrial function.

12p vioraclene 31-03-2024 4 2   Download

Mitochondrial presequence proteases perform fundamental functions as they process about 70 % of all mitochondrial preproteins that are encoded in the nucleus and imported posttranslationally. The mitochondrial intermediate presequence protease MIP/Oct1, which carries out precursor processing, has not yet been established to have a role in human disease.

13p vioraclene 31-03-2024 2 2   Download

ATPase family AAA-domain containing protein 3A (ATAD3A) is a nuclear-encoded mitochondrial membrane-anchored protein involved in diverse processes including mitochondrial dynamics, mitochondrial DNA organization, and cholesterol metabolism.

21p vibransone 28-03-2024 4 2   Download

In ebook "Mitochondria: The dynamic organelle" the term mitochondrion is derived from Latin, with mitos meaning thread and chondrion meaning granules. Indeed, under the light microscope, mitochondria often appear as rods or granules within the cytoplasm. For decades after initial visualization of mitochondria by light microscopy, mitochondrial function remained clouded.

359p cotieubac1004 15-03-2024 4 0   Download

In ebook "Molecular aspects of the stress response: Chaperones, membranes and networks (Advances in experimental medicine and biology, Volume 594)" the reader will learn the role of chaperone classes such as Hsp27 or Hsp90, the action of highly organized chaperone networks in various cellular compartments such as the ER or mitochondrial/ER networks as well as the molecular details of the signaling mechanisms leading to chaperone induction during stress.

218p tachieuhoa 28-01-2024 3 2   Download

Ebook "Mitochondria: Practical protocols (Second edition)" compiles a broad range of step-by-step protocols, complementary to the ones published in the first edition of this book, to study various aspects of mitochondrial structure and function in different model organisms, both in vitro and in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

410p lucchinguyen 28-12-2023 4 2   Download

Acid phosphatase type 6 (ACP6) is a mitochondrial lipid phosphate phosphatase that played a role in regulating lipid metabolism and there is still blank in the clinico-pathological significance and functional roles of ACP6 in human cancers. No investigations have been conducted on ACP6 in hepatocellular carcinoma (HCC) up to date.

14p vileonardodavinci 23-12-2023 8 3   Download

Part 2 book "Marks' basic medical biochemistry - A clinical approach" includes content: Basic concepts in the regulation of fuel metabolism by insulin; glucagon, and other hormones, cellular bioenergetics - adenosine triphosphate and O2; digestion, absorption, and transport of carbohydrates; generation of adenosine triphosphate from glucose, fructose, and galactose - glycolysis; tricarboxylic acid cycle; oxidative phosphorylation and mitochondrial function; oxygen toxicity and free radical injury; formation and degradation of glycogen.... and other contents.

366p oursky07 24-10-2023 4 3   Download

Leucine-rich pentatricopeptide repeat containing (LRPPRC) is a potential oncogene in multiple tumor types, including lung adenocarcinoma, esophageal squamous cell carcinoma and gastric cancer. LRPPRC exerts its tumor-promoting effects mainly by regulating mitochondrial homeostasis and inducing oxidative stress.

11p visharma 20-10-2023 4 2   Download

Part 1 book "Equine genomics" includes content: Defining the equine genome - The nuclear genome and the mitochondrial genome, genetic linkage maps, physical and comparative maps, the Y-chromosome, unexpected structural features of the equine major histocompatibility complex, assembly and analysis of the equine genome sequence, genomic tools and resources - Development and applications of an equine SNP genotyping array, functional genomics, coat color genomics.

167p oursky04 14-09-2023 4 2   Download

Cytoplasmic male sterility (CMS) is a maternally inherited inability to produce functional pollen found in numerous flowering plant species. CMS is associated with mitochondrial DNA mutation, novel chimeric open reading frames (ORFs), and rearrangement of coding and noncoding regions of the mitochondrial genome.

10p vinarcissa 21-03-2023 2 1   Download

The switch from oxidative phosphorylation to glycolysis in proliferating cancer cells, even under aerobic conditions, has been shown first in 1926 by Otto Warburg. Today this phenomenon is known as the “Warburg effect” and recognized as a hallmark of cancer.

9p vinarcissa 21-03-2023 6 1   Download

Quercetin, a multifunctional therapeutic agent, is used in various types of cancer. However, its therapeutic effect is limited by virtue of poorly aqueous solubility and instability in the physiological medium. To overcome these limitations, we aimed (i) to design quercetin loaded liposomes with unlinked-PEG4000 with regard to not only surface modification but also solubility enhancement, and (ii) to investigate the antineoplastic effects on HeLa cells.

13p lyhuyenthu 31-01-2023 2 2   Download

C-to-U RNA editing is prevalent in the mitochondrial and chloroplast genes in plants. The biological functions of a fraction of C-to-U editing sites are continuously discovered by case studies. However, at genome-wide level, the cis and trans determinants affecting the occurrence or editing levels of these C-to-U events are relatively less studied.

10p vihagrid 30-01-2023 11 3   Download

Functional genetic variation plays an important role in predicting patients’ response to chemotherapeutic agents. A growing catalogue of mitochondrial DNA (mtDNA) alterations in various cancers point to their important roles in altering the drug responsiveness and survival of cancer cells.

4p vihagrid 30-01-2023 9 4   Download