Model compound

In this study, the extraction of chlorogenic acid from Vietnamese green coffee beans was optimized using the response surface methodology. A second-order polynomial model with three important variables (liquid-to-solid ratio, temperature, and extraction time) was used.

11p vibecca 01-10-2024 1 1   Download

Carbon capture and storage is a critical component of negative emission technologies for achieving economy-wide carbon neutrality to mitigate climate change and limit global temperature increase. Removal of CO2 can be undertaken after the standard pollution controls.

5p vikwong 29-09-2024 1 1   Download

Resveratrol is a naturally occurring compound with anti-inflammatory properties. However, the protective molecular mechanisms of resveratrol against LPS-induced inflammation have not been thoroughly known. In the present study, we examined the antiinflammatory effect of resveratrol in inflammatory model using murine macrophage-like cell RAW264.7 stimulated with LPS. Resveratrol suppressed the production of inflammatory cytokines in LPS-stimulated RAW264.7 cells with the IC50 value as 17.5 ± 0.7 μM for IL-6, 14.2 ± 1.9 μM for IL-10, and 18.9 ± 0.6 μM for TNF-α.

9p xuanphongdacy06 18-09-2024 1 1   Download

Master's thesis of Science "Investigation into the modulation of circadian clock proteins by dietary compounds and small molecules" is structured as follows: Chapter 1 Introduction; Chapter 2 Identification of novel bioactive compounds from Olea europaea by evaluation of chemical compounds in the OliveNetTM library: in silico bioactivity and molecular modelling, and in vitro validation of hERG activity; Chapter 3 Modulation of circadian core clock proteins by dietary compounds; Chapter 4 Molecular mechanisms of action of selected olive phenolics against epigenetic modifiers and the structur...

235p runthenight04 02-02-2023 3 2   Download

Building approximation formulas using equivalentinclusion method to determine the effective values of the conductivity, the elastic modulus of compound-inclusion composite materials and applying numerical methods using finite elements (FE) calculated for some specific material models.

27p capheviahe26 25-01-2021 15 4   Download

The feasibility of the synthesis of the 309,312126 isotopes via the mentioned systems is investigated based on the widths. The widths in the excitation energy range of E= 10 – 100 MeV are calculated in the scope of the statistical model, in which the level density is calculated by using the Fermi-gas model. By employing the LISE++ code, the level densities the compound nuclei, 309,312126 nuclei, are calculated to be about 105 – 1050 (MeV−1 ) in the energy range of interest

8p larachdumlanat127 02-01-2021 5 1   Download

This paper demonstrates that for a CNN it is vice-versa, in which concatenation is better for CDR classification. To this end, we develop a CNN based model with multiple input concatenated for CDR classification. Experimental results on the benchmark dataset demonstrate its outperformance over other recent state-of-the-art CDR classification models.

6p tamynhan6 14-09-2020 16 4   Download

The flesh fly Sarcophaga ruficornis is a pest of veterinary importance as it affects various animals reared for livestock including cows, buffaloes, sheep, and goats causing myiasis, which results in huge economic loss to the livestock owners. Various attempts have been made to control this fly using different chemical formulations. Barium carbonate is highly toxic compound upon acute and chronic exposures. Barium compounds have been found to have a toxic effect on different animal models.

10p kequaidan7 01-09-2020 16 2   Download

In this paper, we propose a three-phase multi-attribute ranking approach having as outcomes of the modeling phase what we refer to as net superiority and inferiority indexes. These are defined as bounded differences between the classical superiority and inferiority indexes.

12p tohitohi 22-05-2020 21 0   Download

A real inventory system for single item with specific demand characteristics motivates this works. The demand can be seen as two types of independent demand, where compound Poisson process describes the characteristics of each demand.

10p tohitohi 22-05-2020 20 0   Download

Natural precious products such as aroma compounds, essential oils, and bio-activated materials are usually extracted from about 30,000 botanical species. These extracts are often high competitive market due to their small content (less than 1 %) in plants and high purification cost. Thus, development of a modeling for the optimization of the crude oil extraction is highly paid attention. In this work, a modeling of Vietnam lemongrass oil extraction using steam distillation is developed and the optimization of the process parameters is performed using response surface methodology (RSM).

6p abcxyz123_02 03-03-2020 31 2   Download

The reliability of Quantitative Structure – Activity or Property Relationships for prediction of physico-chemical properties and anticancer activity of flavone and isoflavone derivatives was improved by using the quantitative relationships between structurally similar flavone and isoflavone structures (QSSRs). The targeted-compound method was developed by a training set, which contains only similar compounds structurally to target compound.

7p nguathienthan1 20-11-2019 22 2   Download

In an attempt to improve material properties used for oral administration, which is restricted by fast dissolution in the stomach, chitosan hydrogels were coated with cellulose dissolved in ionic liquid. Using insulin as a model compound, the properties of these cellulose-coated microparticles for the controlled release of drug were investigated. The results showed that the coated microparticles were more stable than those which were uncoated at low pH and suitable for oral delivery without requiring any harmful and sophisticated cross-linkage treatment.

8p quaymax4 05-09-2018 32 0   Download

Hydrotalcite-type (HT) materials based on ZnAlO and MgAlO have been prepared and investigated by various physico-chemical method: IR, XRD, BET... It was found that the HT structure depended on the nature and the atom ratio of the metals. The adsorption ability of the materials was tested with the reactive dyes Red 3BA as a model compound. The results indicated that the materials with the HT structure and atom ratio of Me2+ /Me3+ = 3 : 1 calcinated at < 500o C have the highest dyes removal. That could be related with the chemical characterization.

5p uocvong04 24-09-2015 79 5   Download

The aim of Caffeine and chlorogenic acid separation from raw coffee beans using supercritical CO2 in water was to develop new process for extracting and separating hydrophilic and hydrophobic compounds from coffee beans using supercritical CO in water. In this work, experiments and simulation of the process has been conducted. Chlorogenic acid and caffeine from coffee beans were used as model compounds of hydrophilic and hydrophobic compounds, respectively.

8p phannguyen05 16-03-2015 60 5   Download

Recovering useful hydrocarbons from sewage sludge using zirconia-supporting iron oxide catalysts was investigated. Zirconia has activity for decomposing water molecules to generate active oxygen and hydrogen species.

6p tuananhhumg 04-11-2013 37 2   Download

The invertebrate nuclear receptor, ultraspiracle (USP), an ortholog of the vertebrate RXR, is typically modelled as an orphan receptor that functions without a ligand-binding activity. The identification of a ligand that can transcrip-tionally activate USP would provide heuristic leads to the structure of potentially high affinity activating compounds, with which to detect unknown regulatory pathways in which this nuclear receptor participates.

11p tumor12 22-04-2013 38 2   Download

The sulfonephthalein indicator, phenol red, exhibits an unusually slow rate of oxidation by laccase fromPolipo-rus pinsitus, in spite of the fact that it is a phenol and therefore a natural substrate for this phenoloxidase enzyme. Nevertheless, after prolonged exposure to laccase (24 h) phenol red is oxidized by more than 90%.

7p tumor12 20-04-2013 40 2   Download

CYP73 enzymes are highly conserved cytochromes P450 in plant species that catalyse the regiospecific 4-hydroxylation ofcinnamicacid to formprecursorsofligninandmanyother phenolic compounds. A CYP73A1 homology model based on P450 experimentally solved structures was used to iden-tify active site residues likely togovern substrate binding and regio-specific catalysis. The functional significance of these residues was assessed using site-directedmutagenesis.

12p tumor12 20-04-2013 40 3   Download

Purified manganese peroxidase (MnP) fromPhanerocha-ete chrysosporiumoxidizes nonphenolicb-1 diarylpropane lignin model compounds in the presence of Tween 80,and in three- to fourfold lower yield in its absence. In thepresence of Tween 80,1-(3¢,4¢-diethoxyphenyl)-1-hydroxy-2-(4¢-methoxyphenyl)propane (I) was oxidized to 3,4-diethoxy-benzaldehyde (II),4-methoxyacetophenone (III) and 1-(3¢,4¢-diethoxyphenyl)-1-oxo-2-(4¢-methoxyphenyl)pro-pane (IV),while only 3,4-diethoxybenzaldehyde (II) and 4-methoxyacetophenone (III) were detected when the reac-tion was conducted in the absence of Tween 80..

9p tumor12 20-04-2013 41 4   Download