Nervous tissue

Regulator of G protein signaling (RGS) proteins are gatekeepers regulating the cellular responses induced by G protein-coupled receptor (GPCR)-mediated activation of heterotrimeric G proteins. Specifically, RGS proteins determine the magnitude and duration of GPCR signaling by acting as a GTPase-activating protein for Gα subunits, an activity facilitated by their semiconserved RGS domain. The R7 subfamily of RGS proteins is distinguished by two unique domains, DEP/DHEX and GGL, which mediate membrane targeting and stability of these proteins.

13p caothientrangnguyen 09-05-2020 24 1   Download

Regulator of G-protein signaling (RGS) proteins were originally identified as negative regulators of G-protein-coupled receptor (GPCR) signaling via their GTPase-accelerating protein (GAP) activity. All RGS proteins contain evolutionarily conserved RGS domain; however, they differ in their size and regulatory domains. RGS1 and RGS10 are smaller than other RGS proteins, and their functions involve various inflammatory responses including autoimmune responses in both the periphery and the central nervous system (CNS). Neuroinflammation is the chronic inflammatory response in the CNS.

5p caothientrangnguyen 09-05-2020 24 1   Download

This chapter students will be able to: List the basic functions of the nervous system; explain the structural and functional divisions of the nervous system; list the types of neuroglia and cite their functions; define neuron, describe its important structural components, and relate each to a functional role;...

47p tangtuy07 02-04-2016 46 2   Download

Chapter 11 - Fundamentals of the nervous system and nervous tissue (part b). In this chapter, you will learn: Define resting membrane potential and describe its electrochemical basis, compare and contrast graded potentials and action potentials, explain how action potentials are generated and propagated along neurons,...

55p tangtuy07 02-04-2016 42 2   Download

In this chapter, students will be able to understand: Define synapse, distinguish between electrical and chemical synapses by structure and by the way they transmit information, distinguish between excitatory and inhibitory postsynaptic potentials, describe how synaptic events are integrated and modified,...

80p tangtuy07 02-04-2016 31 2   Download

Peptides which should be generated from the neuropeptide FF (NPFF) precursor were identified in a neuronal (human neuroblastoma SH-SY5Y) cell line and in COS-7 cells after transient transfection of the human proNPFFAcDNA and were comparedwith those detected in themouse spinal cord. After reverse-phase high performance liquid chromatogra-phy of soluble material, NPFF-related peptides were im-munodetected with antisera raised against NPFF and identified by using on-line capillary liquid chromatography/ nanospray ion trap tandem mass spectrometry. ...

13p tumor12 20-04-2013 32 2   Download

The PAT2 transporter has been shown to act as an electro-genic proton/amino acid symporter. The PAT2 cDNA has been cloned fromvarious human, mouse and rat tissues and belongs to a group of four genes (pat1topat4)withPAT3 and PAT4 still resembling orphan transporters. The first immunolocalization studies demonstrated that the PAT2 protein is found in the murine central nervous system in neuronal cells with a proposed role in the intra and/or intercellular amino acid transport.

8p awards 05-04-2013 53 5   Download

The hypothesis thatL-glutamate (Glu) is an excitatory amino acid neurotransmitter in the mammalian central nervous system is now gaining more support after the suc-cessful cloning of a number of genes coding for the signaling machinery required for this neurocrine at synapses in the brain. These include Glu receptors (signal detection), Glu transporters (signal termination) and vesicular Glu trans-porters (signal output through exocytotic release).

13p dell39 03-04-2013 64 4   Download

We previously reported that zebrafishaB-crystallin is not constitutively expressed in nervous or muscular tissue and has reduced chaperone-like activity compared with its human ortholog. Here we characterize the tissue expression pattern and chaperone-like activity of a second zebrafish aB-crystallin.

10p dell39 27-03-2013 35 4   Download

Protein kinase Ce is expressed at higher levels in the brain compared to other tissues such as the heart and kidney, suggesting that it plays an important role in the nervous system. Several neural functions of PKCe, including neurotransmitter release and ion channel regulation, have been identified using PKCe knockout mice.

7p galaxyss3 07-03-2013 46 4   Download

Mô thần kinh là một tổ chức thể hiện tính tiến hoá rõ rệt nhất. Ở động vật đơn bào chưa có hệ thần kinh riêng. Ở động vật đa bào thấp đã có một số tế bào biệt hoá để tiếp nhận các kích thích của ngoại cảnh gọi là tế bào thần kinh nhạy cảm. Ở động vật cao hơn, các tế bào thần kinh tập trung lại thành từng hạch, hình thành các trung tâm nhận cảm và vận động riêng. Tiến hoá hơn nữa, hệ thần kinh đã biến thành hệ thống thần kinh với não...

17p 124357689 05-06-2012 160 38   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation...

10p toshiba10 15-10-2011 37 2   Download

Chương 4: MÔ THẦN KINH (Nervous tissue) Mô thần kinh là một tổ chức thể hiện tính tiến hoá rõ rệt nhất. Ở động vật đơn bào chưa có hệ thần kinh riêng. Ở động vật đa bào thấp đã có một số tế bào biệt hoá để tiếp nhận các kích thích của ngoại cảnh gọi là tế bào thần kinh nhạy cảm. Ở động vật cao hơn, các tế bào thần kinh tập trung lại thành từng hạch, hình thành các trung tâm nhận cảm và vận động riêng. ...

6p poseidon03 20-07-2011 135 31   Download

PND of the Central Nervous System and Dorsal Root Ganglia When symptoms involve brain, spinal cord, or dorsal root ganglia, the suspicion of PND is usually based on a combination of clinical, radiologic, and CSF findings. In these cases, a biopsy of the affected tissue is often difficult to obtain, and although useful to rule out other disorders (e.g., metastasis, infection), neuropathologic findings are not specific for PND. Furthermore, there are no specific radiologic or electrophysiologic tests that are diagnostic of PND. ...

5p thanhongan 07-12-2010 75 4   Download

TRC (Aastrom) Autologous adult bone marrow cells for bone grafting LiverX2000 (Algenix) Extracorporeal liver assist device Encapsulated islet (Amcyte) proliferated Encapsulated islet cells Myocell (Bioheart) Encapsulated infarction cells for myocardial BioSeed-C, BioSeed-Oral Autologous tissue repair for bone and cartilage Bone (Biotissue Technologies) E-matrix (Encelle) Repair or regeneration of diseased or damaged tissue MarkII (Excorp) Extracorporeal liver assist device ICX-PRO, (Intercytex) ICX-TRC Wound repair and hair regeneration HuCNS-SC Inc) (Stem Cell c...

5p konheokonmummim 03-12-2010 112 6   Download