Pain and analgesics

Compare the analgesic and motor block effects of ropivacaine 0.1% - fentanyl 1 mcg/ml with bupivacaine 0.1% - fentanyl 1 mcg/ml in the patient controlled epidural analgesia after hip replacement surgery in the elderly.

27p kequaidan12 03-06-2021 16 3   Download

Comparing the abdominal postoperative analgesic effect between continuous infusion of 0.2% levobupivacaine into incision through the multi-hole catheter with the two methods: (1) intravenous morphine method controlled by the patient and (2) continuous infusion outside the epidural of levobupivacaine mixture 0.125% - fentanyl 2mcg / ml.

27p kequaidan12 03-06-2021 27 3   Download

This topic with the aim of: Comparing the postoperative analgesis effect of ultrasound- guided continous thoracic paravertebral block with epidural anesthesia using bupivacaine and fentanyl after lung surgery. Evaluating changes in circulation, respiratory and some undesirable effects from these two methods of postoperative pain relief.

28p slimzslimz 21-12-2019 25 9   Download

A major unmet clinical need exists for long-acting neurotherapeutics to alleviate chronic pain in patients unresponsive to available nonaddictive analgesics. Herein, a new strategy is described for the development of potent and specific inhibitors of the neuronal exocytosis of transmitters and pain mediators that exhibit unique antinociceptive activity.

13p cosis54 09-12-2012 48 4   Download

Opioid analgesics such as morphine and meperidine have been used to control moderate to severe pain for many years. However, these opioids have many side effects, including the development of tolerance and dependence after long-term use, which has limited their clinical use. We previously reported that mutations in the muopioid receptors (MOR) S196L and S196A rendered them responsive to the opioid antagonist naloxone without altering the agonist phenotype. In MORS196A knock-in mice, naloxone and naltrexone were antinociceptive but did not cause tolerance or physical dependence.

6p toshiba23 18-11-2011 50 1   Download

Diffuse noxious inhibitory controls (DNIC) can be produced by different types of conditioning stimuli, but the analgesic properties and underlying mechanisms remain unclear. The aim of this study was to differentiate the induction of DNIC analgesia between noxious electrical and inflammatory conditioning stimuli. Methods: First, rats subjected to either a supramaximal electrical stimulation or an injection of high-dose formalin in the hind limb were identified to have pain responses with behavioral evidence and spinal Fos-immunoreactive profiles. Second, suppression of tail-flick...

13p toshiba23 18-11-2011 48 5   Download

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Postoperative pain scores and analgesic requirements after thyroid surgery: Comparison of three intraoperative opioid regimens...

3p thulanh9 07-10-2011 38 4   Download