Peripherals

Bài giảng Tin học đại cương: Chương 2 - Kiến trúc máy tính bao gồm những nội dung về máy tính là gì? Mô hình kiến trúc cơ bản của máy tính; central processing unit; computer memory; computer bus; peripheral devices; software. Mời các bạn tham khảo bài giảng để bổ sung thêm kiến thức về lĩnh vực này.

5p cocacola_09 26-11-2015 64 2   Download

PCI trong khoa học máy tính (là viết tắt Tiếng Anh của: Peripheral Component Interconnect).là một chuẩn để truyền dữ liệu giữa các thiết bị ngoại vi đến một bo mạch chủ (thông qua.chip cầu nam). Khe cắm mở rộng PCI 33Mhz, 32 bit màu trắng (bên phải) loại thông dụng thường thấy trên.các máy tính cá nhân.

4p dinh_trung_tu 12-09-2013 86 5   Download

Theo nghĩa sinh học, mạng nơ-ron là một tập hợp các dây thần kinh kết nối với nhau. Ngày nay, thuật ngữ này còn dùng để chỉ mạng nơ-ron nhân tạo, cấu thành từ các nơ-ron nhân tạo. Do đó thuật ngữ 'mạng nơ-ron' xác định hai khái niệm phân biệt: Mạng nơ-ron sinh học là một mạng lưới (plexus) các nơ-ron có kết nối hoặc có liên quan về mặt chức năng trực thuộc hệ thần kinh ngoại biên (peripheral nervous system) hay hệ thần kinh trung ương (central nervous system). Trong ngành thần kinh học...

13p and_12 08-08-2013 86 10   Download

MFG-E8 (milk fat globule-EGF factor 8) is a peripheral membrane glycoprotein, which is expressed abundantly in lactating mammary glands and is secreted in association with fat globules. This protein consists of two-repeated EGF-like domains, a mucin-like domain and two-repeated discoidinlike domains (C-domains), and contains an integrin-binding motif (RGD sequence) in the EGF-like domain. To clarify the role of each domain on the peripheral association with the cell membrane, several domain-deletion mutants of MFG-E8 were expressed in COS-7 cells. ...

10p research12 01-06-2013 53 3   Download

The intrachloroplastic localization of post-transcriptional gene expression steps represents one key determinant for the regulation of chloroplast development. We have character-ized an RNA binding protein of 63kDa (RBP63) from Chlamydomonas reinhardtiichloroplasts, which cofraction-ates with stromal thylakoid membranes. Solubility proper-ties suggest that RBP63is a peripheral membrane protein.

8p research12 23-04-2013 34 3   Download

Antibacterial peptides were isolated fromhuman peripheral granulocytes of a healthy donor who had been treated with granulocyte-colony stimulating factor (G-CSF) and cortisol. Peptides were solubilized in acidi®ed chloroform/methanol, and partitioned in chloroform/methanol/water. Water-soluble polypeptides were separated by cation-exchange and reversed-phase chromatography. Several previously char-acterized antibacterial polypeptides were identi®ed; defen-sins 1±3, defensin 4, lysozyme, eosinophil cationic protein, and calgranulin A. ...

7p research12 23-04-2013 26 3   Download

The enzymes pyruvate decarboxylase (E1) and dihydro-lipoyl dehydrogenase (E3) bind tightly but in a mutually exclusive manner to the peripheral subunit-binding domain (PSBD) of dihydrolipoyl acetyltransferase in the pyruvate dehydrogenase multienzyme complex of Bacillus stearo-thermophilus.

9p fptmusic 12-04-2013 43 2   Download

E2020 (R,S)-1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]-methyl)piperidine hydrochloride isa piperidine-based ace-tylcholinesterase (AChE) inhibitor that was approved for the treatment of Alzheimer’s disease in the United States. Structure-activity studiesof thisclassof inhibitorshave indicated that both the benzoyl containing functionality and the N-benzylpiperidine moiety are the key featuresfor binding and inhibition of AChE.

12p fptmusic 12-04-2013 41 1   Download

Transmissible spongiform encephalopathies (TSE) are fatal neuro-degenerative diseases of humans and animals. The underlying infectious agent, the prion, accumulates not only in the central ner-vous system (CNS) but also in secondary lymphoid organs. I will revisit the role of the immune system in peripheral prion pathogen-esis, while focusing on the mechanisms by which extraneural and extralymphatic prion infectivity develops.

64p fptmusic 11-04-2013 36 4   Download

Peripheral nerve injury is normally followed by a robust regenerative response. Here we describe the early changes associated with injury from the initial rise in intracellular calcium and the subsequent activation of transcription factors and cytokines leading to an inflammatory reaction, and the expression of growth factors, cytokines, neuropeptides, and other secreted molecules involved in cell-to-cell communication promoting regen-eration and neurite outgrowth.

11p awards 06-04-2013 32 2   Download

A 15 N-labelled peripheral-subunit binding domain (PSBD) of the dihydro-lipoyl acetyltransferase (E2p) and the dimer of a solubilized interface domain (E3int) derived from the dihydrolipoyl dehydrogenase (E3) were used to investigate the basis of the interaction of E2p with E3 in the assem-bly of the pyruvate dehydrogenase multienzyme complex ofBacillus stearo-thermophilus. Thirteen of the 55 amino acids in the PSBD show significant changes in either or both of the 15 N and 1 H amide chemical shifts when the PSBD forms a 1 : 1 complex with E3int. ...

10p awards 05-04-2013 43 3   Download

The amino acid residue tryptophan 27 of 6,7-dimethyl-8-ribityllumazine synthase of the yeastSchizosaccharomyces pombewas replacedby tyrosine. The structures of theW27Y mutant protein in complex with riboflavin, the substrate analogue 5-nitroso-6-ribitylamino-2,4(1H,3H)-pyrimidin-edione, and the product analogue 6-carboxyethyl-7-oxo-8-ribityllumazine,weredeterminedbyX-raycrystallography at resolutions of 2.7–2.8 A ˚ .

7p awards 05-04-2013 45 6   Download

We report here thatEscherichia coli pyrophosphatase aggregates in the presence of millimolar Cd 2+ . This highly cooperative process was specific to both the metal ion and the protein and could be reversed fully by decreasing the Cd 2+ concentration. Aggregation was enhanced by Mg 2+ , the natural cofactor of pyrophosphatase, and Mn 2+ . Mutations at the intersubunit metal-binding site had no effect, whereas mutation at Glu139, which is part of the peripheral metal-binding site found in pyrophosphatase crystals near the contact region between two enzyme mole-cules, suppressed aggregation.

0p awards 05-04-2013 35 2   Download

The rate-limiting step for hydrolysis of thepositivelycharged oxoester benzoylcholine (BzCh) by human butyrylcho linesterase (BuChE) is deacylation (k3 ), whereas it is acyla-tion (k2 ) for hydrolysis of the homologous thioester ben-zoylthiocholine (BzSCh). Steady-state hydrolysis of BzCh and BzSCh by wild-type BuChEand its peripheral anionic site mutant D70G was investigated at different hydrostatic pressures, which allowed determination of volume changes associated with substrate binding, and the activation vol-umes for the chemical steps....

11p dell39 03-04-2013 32 4   Download

The divalent metal transporter (DMT1) is a 12-transmem-brane domain protein responsible for dietary iron uptake in the duodenum and iron acquisition from transferrin in peripheral tissues. The transmembrane domain 4 (TM4) of DMT1 has been shown to be crucial for its biological function. Here we report the 3D structure and topology of the DMT1-TM4 peptide by NMR spectroscopy with simulated annealing calculations in membrane-mimetic environments, e.g. 2,2,2-trifluoroethanol and SDS micelles.

14p dell39 03-04-2013 35 3   Download

The transient receptor potential channel vanilloid receptor subunit 1 (TRPV1) is amolecular integrator of physical and chemical stimuli in the peripheral nociceptor terminals. TRPV1 is an ionotropic channel that plays a critical role in both thermal nociception and inflammatoryhyperalgesia. Structure–function relationships are providing fundamental insights of the modular architecture of this neuronal recep-tor.

7p dell39 03-04-2013 46 3   Download

The hypothesis thatL-glutamate (Glu) is an excitatory amino acid neurotransmitter in the mammalian central nervous system is now gaining more support after the suc-cessful cloning of a number of genes coding for the signaling machinery required for this neurocrine at synapses in the brain. These include Glu receptors (signal detection), Glu transporters (signal termination) and vesicular Glu trans-porters (signal output through exocytotic release).

13p dell39 03-04-2013 64 4   Download

UDP-galactose 4-epimerase (GALE, EC 5.1.3.2) catalyses the interconver-sion of UDP-glucose and UDP-galactose. Point mutations in this enzyme are associated with the genetic disease, type III galactosemia, which exists in two forms – a milder, or peripheral, form and a more severe, or general-ized, form.

8p dell39 27-03-2013 50 5   Download

PIC là một họ vi điều khiển RISC đƣợc sản xuất bởi công ty Microchip Technology. Thế hệ PIC đầu tiên là PIC1650 đƣợc phát triển bởi Microelectronics Division thuộc General – Instrument. PIC là viết tắt của "Programmable Intelligent Computer" là một sản phẩm của hãng General Instruments đặt cho dòng sản phẩm đầu tiên là PIC1650. Thời điểm đó PIC1650 đƣợc dùng để giao tiếp với các thiết bị ngoại vi cho máy chủ 16 bit CP1600, vì vậy, ngƣời ta cũng gọi PIC với cái tên "Peripheral Interface Controller" – bộ điều khiển giao tiếp ngoại vi....

12p hoangphi0901 26-03-2013 530 87   Download

LeIF, aLeishmaniaprotein similar to the eukaryotic initiation factor eIF4A, which is a prototype of the DEAD box protein family, was origin-ally described as a Th1-type natural adjuvant and as an antigen that indu-ces an IL12-mediated Th1 response in the peripheral blood mononuclear cells of leishmaniasis patients.

15p inspiron33 23-03-2013 32 3   Download