Phản ứng thế nucleophil

Bài giảng Hoá hữu cơ A: Chương 3 cung cấp những kiến thức như thế ái nhân (Nucleophilic substitution – SN); thế ái điện tử (Electrophilic substitution – SE); cộng hợp ái nhân (Nucleophilic addition – AN); cộng hợp ái điện tử (Electrophilic addition – AE); tách loại (Elimination – E). Mời các bạn cùng tham khảo!

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Carbonylation is one of the most important reactions leading to C-C bond formation. Direct synthesis of carbonyl compounds with CO gives rise to carboxylic acids and their derivatives, such as esters, amides, lactones, lactams etc. The process can be represented by the simple reactions of Scheme 5.1. In general, carbonylation proceeds via activation of a C-H or a C-X bond in the olefins and halides or alcohols, respectively, followed by COinsertion into the metal-carbon bond.

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