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Phenotypic traits
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Ebook "Longevity genes: A blueprint for aging" describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.
199p
ladongphongthanh1008
22-04-2024
2
2
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Recent studies have used genome-wide data to investigate evolutionary mechanisms related to behavioral phenotypes, identifying widespread signals of positive selection. Here, we conducted a genome-wide investigation to study whether the molecular mechanisms involved in these traits were affected by local adaptation.
12p
vibransone
28-03-2024
2
2
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Common and rare variants contribute to the etiology of complex traits. However, the extent to which the phenotypic effects of common and rare variants involve shared molecular mediators remains poorly understood. The question is essential to the basic and translational goals of the science of genomics, with critical basic-science, methodological, and clinical consequences.
13p
vicwell
29-02-2024
4
2
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Human proteins are widely used as drug targets. Integration of large-scale protein-level genome-wide association studies (GWAS) and disease-related GWAS has thus connected genetic variation to disease mechanisms via protein. Previous proteome-by-phenome-wide Mendelian randomization (MR) studies have been mainly focused on plasma proteomes.
22p
vicwell
29-02-2024
3
1
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This study was conducted to compare the genetic gain per sow per year of Duroc pigs in twelve scenarios. These scenarios were based on the number of traits used such as average daily gain (ADG), feed conversion ratio (FCR), intramuscular fat content (IMF) and were also based on the number of records of phenotype for these traits from the individual animal and its relatives.
9p
vimichaelfaraday
28-12-2023
4
2
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Cancer cells release heterogeneous populations of extracellular vesicles (EVs) that transmit aggressive phenotypic traits to recipient cells. We aimed to establish if the heterogenous EVs population or a sub-population is responsible, if we could block undesirable cell-to-cell communication by EVs, and, if some EVs continued to be released, would their undesirable influences on recipient cells continue.
12p
vioracle
29-09-2023
6
4
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Part 1 book "Advances in poultry genetics and genomics" includes content: The origin and domestication of poultry species; molecular identifiation of major morphological mutations in poultry, the genetic basis for pigmentation phenotypes in poultry, physiological challenges in poultry breeding, genetics and genomics of meat quality traits in poultry species, genetics and genomics of egg production traits in poultry species, genetics and genomics of feed utilization effiiency in poultry species, genetics and genomics of behavioral and welfare traits in poultry species.
290p
oursky04
14-09-2023
6
3
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Part 1 book "Aquaculture and fisheries biotechnology - Genetic approaches" includes content: History of biotechnology, genetics and selective breeding in aquaculture and fisheries; phenotypic variation and environmental effects basic genetics, qualitative traits and selection for qualitative traits; strain evaluation; domestication and strain selection; intraspecific crossbreeding; interspecific hybridization,.... and other contents.
247p
oursky04
14-09-2023
5
3
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Part 2 book "Bovine genomics" includes contents: Bovine genome architecture, bovine epigenetics and epigenomics, mapping quantitative trait loci, genome wide association studies and linkage disequilibrium in cattle, genomic selection in beef cattle, impact of high throughput genotyping and sequencing on the identification of genes and variants underlying phenotypic variation in domestic cattle.
149p
oursky04
14-09-2023
9
3
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Genetic ancestry is a critical co-factor to study phenotype-genotype associations using cohorts of human subjects. Most publicly available molecular datasets are, however, missing this information or only share self-reported race and ethnicity, representing a limitation to identify and repurpose datasets to investigate the contribution of ancestry to diseases and traits.
5p
visteverogers
24-06-2023
3
2
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Vietnam journal of Agriculture and Rural development: Vol 2. No. 2 (2022): Design of CRISPR/Cas9 system for editing OsNRAMP7 involved in metal transport in TBR225 rice variety; Breeding thirteen mutant lines from DX208 Mungbean (Vigna radiata) with synchrony in pod maturity by DNA marker; Phenotypic variation and correlation of fruit traits in diverse muskmelon materials;...
104p
viblackwidow
07-04-2023
5
3
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This study applied principal component analysis and cluster analysis to investigate the primary and secondary relationships of the main agronomic traits affecting yield and quality and phenotypic diversity of 20 muskmelon materials in the Spring and Autumn season 2021 in Gia Lam, Ha Noi. The result of this study provided valuable information for muskmelon prebreeding in Vietnam.
9p
viblackwidow
07-04-2023
6
2
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The mitochondrial genome (mtDNA) is an emerging determiner of phenotypic traits and disease. mtDNA is inherited in a strict maternal fashion from the population of mitochondria present in the egg at fertilisation.
12p
vinarcissa
21-03-2023
1
1
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Genome Wide Association Studies (GWAS) are based on the observation of genome-wide sets of genetic variants – typically single-nucleotide polymorphisms (SNPs) – in diferent individuals that are associated with phenotypic traits.
20p
vinarcissa
21-03-2023
5
1
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Genome-wide association studies (GWAS) are a powerful tool for detecting genomic regions explaining variation in phenotype. The objectives of the present study were to identify or refine the positions of genomic regions affecting milk production, milk components and fertility traits in Canadian Holstein cattle, and to use these positions to identify genes and pathways that may influence these traits.
11p
vinarcissa
21-03-2023
2
1
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QTL mapping through genome-wide association studies (GWAS) is challenging, especially in the case of low heritability complex traits and when few animals possess genotypic and phenotypic information.
9p
vinarcissa
21-03-2023
1
1
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Diversity in crops is fundamental for plant breeding efforts. An accurate assessment of genetic diversity, using molecular markers, such as single nucleotide polymorphism (SNP), must be able to reveal the structure of the population under study
12p
vinarcissa
21-03-2023
8
1
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Cattle are bred for, amongst other factors, specific traits, including parasite resistance and adaptation to climate. However, the influence and inheritance of mitochondrial DNA (mtDNA) are not usually considered in breeding programmes.
11p
vinarcissa
21-03-2023
2
1
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Genome-wide association studies involve detecting association between millions of genetic variants and a trait, which typically use univariate regression to test association between each single variant and the phenotype.
15p
vinarcissa
21-03-2023
1
1
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Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently requires the identification of the respective phenotypic trait of interest and is simply based on a significant difference between a consomic and host strain. However, statistical significance as represented by P values does not necessarily predicate practical importance.
16p
vinarcissa
21-03-2023
4
1
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