Progenitor cells
-
The current study compares cytophysiological features of progenitor, stromal-like cells derived from histiocytic lesions (sl-pHCs) of three pediatric patients with diferent histiocytoses types and outcomes. The characterized cells may fnd potential applications in drug testing.
23p vishanshan 27-06-2024 2 1 Download
-
Ebook "Endogenous stem cell-based brain remodeling in mammals" highlights the endogenous regenerative potential of the central nervous system in neonates and juveniles and discusses possible ways it might be manipulated for medical purposes. The first section provides a descriptive summary of the salient steps of human brain development with a discussion of comparisons with other mammalian brains. It also provides a historical perspective on our understanding of ongoing brain development throughout the lifespan and serve to introduce the concept of brain plasticity following injury.
234p ladongphongthanh1008 22-04-2024 4 2 Download
-
Ebook "Mast cell biology: Contemporary and emerging topics" have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
312p tracanhphuonghoa1007 22-04-2024 2 2 Download
-
Ebook "Hedgehog-gli signaling in human disease" is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine. This is a timely primer on how a system of cell communication, Hedgehog-GLI signaling, plays a critical role in human disease and thus provides the background for the development of novel and rational therapies.
240p tracanhphuonghoa1007 22-04-2024 5 2 Download
-
Ebook "Perinatal tissue-derived stem cells: Alternative sources of fetal stem cells" covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations.
246p tracanhphuonghoa1007 22-04-2024 3 2 Download
-
Ebook "Prominin-1 (CD133): New insights on stem & cancer stem cell biology" was conceived to celebrate the fi fteenth anniversary of the discovery of prominin-1, also known in the medical fi eld as CD133. This book is composed of 15 chapters that will describe, on one hand, the molecular and cellular biology of prominin-1 and other members of the prominin family and, on the other hand, the importance of this molecule in the medical fi eld as a valuable marker of stem and cancer stem cells.
255p tracanhphuonghoa1007 22-04-2024 4 1 Download
-
Ebook "Adult stem cells: Biology and methods of analysis" offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells, while it also describes and critically evaluates the methods currently used to assess stem cell self-renewal.
282p tracanhphuonghoa1007 22-04-2024 5 2 Download
-
T cells exhibit heterogeneous functional states in the tumor microenvironment. Immune checkpoint inhibitors (ICIs) can reinvigorate only the stem cell-like progenitor exhausted T cells, which suggests that inhibiting the exhaustion progress will improve the efficacy of immunotherapy.
16p vibransone 28-03-2024 3 2 Download
-
Human bone marrow stromal cells (BMSCs) are an easily accessible and expandable progenitor population with the capacity to generate neural cell types in addition to mesoderm. Lineage tracing studies in transgenic animals have indicated Nestin+BMSCs to be descended from the truncal neural crest.
12p vicwell 29-02-2024 5 1 Download
-
In ebook "Advances in cancer stem cell biology" tumor-maintaining cells or cancer stem-like cells are a subpopulation of cancer cells that acquired some of the characteristics of stem cells to survive and adapt to ever-changing environments. These include the ability to self-renew and the capacity to produce progenitors that differentiate into other cell types.
349p duongthandue0501 28-02-2024 3 1 Download
-
Ebook "Hematopoietic stem cell biology" discoveries were made possible in part by advancements in technology. For example, recent availability of user friendly fluorescence activated cell sorting (FACS) machines and monoclonal an- bodies with a variety of fluorescent labels has allowed more scientists to sort and analyze rare populations in the bone marrow, such as HSCs. All classes of hematopoietic cells are derived from HSCs.
260p manmanthanhla0201 27-02-2024 2 1 Download
-
Ebook "Stem cells in the respiratory system" focuses on reviewing the most relevant—and recent—ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages.
175p tachieuhoa 28-01-2024 6 2 Download
-
Ebook "Current topics in developmental biology (Volume 1)" provides both a unique perspective and a much needed resource. Work in zebrafish disease models has expanded beyond genetic disorders and developmental defects, and there is now an active and growing community of researchers studying a range of diseases in zebrafish.
373p lucchinguyen 28-12-2023 4 2 Download
-
Cardiac Myxoma is a primary tumor of heart. Its origins, rarity of the occurrence of primary cardiac tumors and how it may be related to limited cardiac regenerative potential, are not yet entirely known. This study investigates the key cardiac genes/ transcription factors (TFs) and signaling pathways to understand these important questions.
46p vileonardodavinci 23-12-2023 3 2 Download
-
Obesity is a risk factor for breast cancer, and women with obesity that develop breast cancer have a worsened prognosis. Within the mammary gland, obesity causes chronic, macrophage-driven inflammation and adipose tissue fibrosis. Weight loss is a recommended intervention to resolve obesity, but the impact of weight loss on the mammary gland microenvironment and in tumors has not been well identified.
16p vileonardodavinci 23-12-2023 2 2 Download
-
Myelodysplastic Neoplasms (MDS) are clonal stem cell disorders characterized by ineffective hematopoiesis and progression to acute myeloid leukemia, myelodysplasia-related (AML-MR). A major mechanism of pathogenesis of MDS is the aberration of the epigenetic landscape of the hematopoietic stem cells and/or progenitor cells, especially DNA cytosine methylation, and demethylation.
18p vialfrednobel 23-12-2023 3 3 Download
-
Human parvovirus B19 (B19) is a single-stranded DNA virus that targets erythroid progenitor cells in the bone marrow. B19 causes erythema infectiosum in children, transient aplastic anemia, pure red cell aplasia, hydrops fetalis, and contributes to other illnesses.
6p viwhitewolf 03-07-2023 3 2 Download
-
Erythropoietin receptor (EPOR) is a functional membrane-bound cytokine receptor. Erythropoietin (EPO) represents an important hematopoietic factor for production, maturation and differentiation of erythroid progenitors. In non-hematopoietic tissue, EPO/EPOR signalization could also play cytoprotective and antiapoptotic role.
9p vihagrid 30-01-2023 7 3 Download
-
Anesthetic preconditioning can improve survival of cardiac progenitor cells exposed to oxidative stress. We investigated the role of protein kinase C and isoform protein kinase C-ε in isoflurane-induced preconditioning of cardiac progenitor cells exposed to oxidative stress.
7p viisaacnewton 25-04-2022 10 2 Download
-
The lifelong accumulation of somatic mutations underlies age-related phenotypes and cancer. Mutagenic forces are thought to shape the genome of aging cells in a tissue-specific way. Whole genome analyses of somatic mutation patterns, based on both types and genomic distribution of variants, can shed light on specific processes active in different human tissues and their effect on the transition to cancer.
22p vielonmusk 30-01-2022 14 0 Download