Prostate cancer

Green tea consumption has been shown to exhibit cancer-preventive activities in preclinical studies. Polyphenon E (Poly E) is a green tea standardized extract. This study was undertaken to examine the antiproliferative effect and pro-oxidant activity of Poly E on PC3 prostate cancer cells.

5p vifaye 20-09-2024 1 1   Download

Brachytherapy is a form of radiotherapy in which radioactive sources are placed at short distances from, or even inside the target volume. The use of high dose rate brachytherapy is a widely accepted and clinically proven treatment for some stages of prostate cancer. The aim of this project was to investigate potential improvements on two of the most important aspects of high dose rate (HDR) and pulsed dose rate (PDR) prostate brachytherapy - prostate definition and treatment delivery verification.

121p runthenight05 01-03-2023 5 3   Download

Bài viết đánh giá ban đầu khả năng liên thông xét nghiệm các dấu ấn ung thư carcinoembryonic antigen (CEA), cancer antigen 19-9 (CA 19-9), prostate specific antigen (PSA) bằng việc đánh giá hệ số biến thiên, phần trăm độ chệch và liên kết chuẩn đo lường của các phương pháp thông qua báo cáo kết quả từ chương trình ngoại kiểm miễn dịch của RIQAS, được quản lý bởi Trung tâm kiểm chuẩn chất lượng xét nghiệm y học thuộc Đại học Y dược TP.HCM.

6p vidudley 20-02-2023 12 2   Download

The aim of this prospective phase II study was to evaluate the efficacy and safety of biweekly docetaxel plus androgen-deprivation therapy (ADT) in patients with metastatic castration-naïve prostate cancer (mCNPC).

7p vielonmusk 21-01-2022 8 1   Download

The population-based survival rate is affected by the quality and effectiveness of health care systems. Overall, the survival of prostate cancer (PC) patients has improved over the past two decades worldwide. This study aimed to determine the overall survival rate and correlate it with the prognostic factors in patients with PC diagnosed in Kurdistan province.

10p vielonmusk 21-01-2022 15 1   Download

Overcoming drug resistance is critical for increasing the survival rate of prostate cancer (PCa). Doc‑ etaxel is the first cytotoxic chemotherapeutical approved for treatment of PCa. However, 99% of PCa patients will develop resistance to docetaxel within 3 years. Understanding how resistance arises is important to increasing PCa survival.

14p vielonmusk 21-01-2022 11 1   Download

Loss of prostate cancer differentiation or de-differentiation leads to an untreatable disease. Patient survival would benefit if this can be prevented or reversed. Cancer de-differentiation transforms luminal-like (differentiated) adenocarcinoma into less luminal-like and more stem-like (undifferentiated) small cell carcinoma through a sequential activation of stem cell transcription factors (scTF) POU5F1, LIN28A, SOX2 and NANOG.

13p vielonmusk 21-01-2022 11 0   Download

Sarcopenia is defined by a loss of muscle strength associated to a decrease in skeletal muscle mass. Ageing greatly contributes to sarcopenia as may many other factors such as cancer or androgen deprivation thera‑ pies (ADT).

7p vielonmusk 21-01-2022 12 1   Download

Do the following: Study on some histopathological features of prostate carcinoma at Military Hospital 103 according to the 2004 WHO classification. Determine the expression of some immunological markers and methylation status of the RASSF1A gene and compare with some histopathological features in prostate carcinoma.

29p petsematary 02-06-2021 16 2   Download

Developing the indications and procedures of 12-core prostate biopsy under transrectal ultrasound guidance. Evaluating the results and giving the comments on relevant factors of 12-core prostate biopsy under transrectal ultrasound guidance.

24p cothumenhmong6 17-07-2020 5 1   Download

Regulators of G protein signaling (RGS) proteins modulate G protein-coupled receptor (GPCR) signaling networks by terminating signals produced by active Gα subunits. RGS17, a member of the RZ subfamily of RGS proteins, is typically only expressed in appreciable amounts in the human central nervous system, but previous works have shown that RGS17 expression is selectively upregulated in a number of malignancies, including lung, breast, prostate, and hepatocellular carcinoma.

10p caothientrangnguyen 09-05-2020 11 0   Download

Bài viết mô tả đặc điểm lâm sàng và cận lâm sàng các trường hợp ung thư tuyến tiền liệt được chẩn đoán và điều trị lần đầu tại bệnh viện Chợ Rẫy.

6p vihermes2711 03-10-2019 32 1   Download

Human glandular kallikrein 2 (hK2) is a trypsin-like serine protease expressed predominantly in the prostate epithelium. Recently, hK2 has proven to be a useful marker that can be used in combination with prostate specific antigen for screening and diagnosis of prostate cancer. The cleavage by hK2 of certain substrates in the proteolytic cascade suggest that the kallikrein may be involved in prostate cancer development; however, there has been very little other progress toward its biochemical characterization or elucidation of its true physiological role.

8p system191 01-06-2013 43 2   Download

PSA (prostate-specific antigen), the most useful serum marker for prostate cancer, is encoded by thehKLK3gene and is present in the serumas amixture of several molecular species. This work was performed to identify the hKLK3 transcripts in order to determine how many proteins resembling PSA are synthesized from thehKLK3gene and secreted in blood. Combined Northern blotting, molecular cloninganddatabase searching showed that thehKLK3gene produces at least 15 transcripts ranging in size from 0.7 to 6.1 kb. Polysomal distribution analysis revealed that the transcripts shorter than 3.

9p tumor12 20-04-2013 54 2   Download

Tumor protein D52 (TPD52) is a protein found to be overexpressed in prostate and breast cancer due to gene amplification. However, its physio-logical function remains under investigation. In the present study, we inves-tigated the response of the LNCaP human prostate carcinoma cell line to deregulation of TPD52 expression.

11p vinaphone15 28-02-2013 41 1   Download

Glutamate carboxypeptidase III (GCPIII) is a metalloenzyme that belongs to the transferrin receptor⁄glutamate carboxypeptidase II (GCPII; EC 3.4.17.21) superfamily. GCPIII has been studied mainly because of its evo-lutionary relationship to GCPII, an enzyme involved in a variety of neuro-pathologies and malignancies, such as glutamatergic neurotoxicity and prostate cancer.

15p vinaphone15 25-02-2013 34 6   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: A Novel Prostate Cancer Classification Technique Using Intermediate Memory Tabu Search

9p dauphong20 11-03-2012 39 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Comparative study of 64Cu/NOTA-[D-Tyr6,beta-Ala11,Thi13,Nle14]BBN(6-14) monomer and dimers for prostate cancer PET imaging

28p sting06 16-02-2012 49 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899

9p dauphong4 03-01-2012 68 7   Download

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer

11p dauphong3 03-01-2012 49 4   Download