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Sepsis has a complex pathophysiology with several diverse and nonspecific mechanisms. Objective: To investigate humoral immune disorders and some related factors in the prognosis of 28-day mortality in children with sepsis.
9p
viwalton
29-06-2024
2
1
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The objective of this study was to externally validate the KELIM (rate of elimination of CA-125) score in patients with high-grade serous ovarian cancer (HGSC) undergoing NACT and explore its relation to the completeness of IDS and survival.
8p
vishanshan
27-06-2024
2
1
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Ovarian cancer (OC) is a gynecological malignancy tumor with high recurrence and mortality rates. Programmed cell death (PCD) is an essential regulator in cancer metabolism, whose functions are still unknown in OC. Therefore, it is vital to determine the prognostic value and therapy response of PCD-related genes in OC.
17p
vishanshan
27-06-2024
1
1
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The treatment for lung oligometastasis from colorectal cancer (CRC) remains challenging. This retrospective study aimed to compare the local tumor control, survival and procedure-related complications in CRC patients undergoing low-dose rate stereotactic ablative brachytherapy (L-SABT) versus percutaneous microwave ablation (MWA) for lung oligometastasis.
13p
vishanshan
27-06-2024
1
1
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Chemo-radiotherapy with curative intent for anal cancer has high complete remission rates, but acute treatment-related gastrointestinal (GI) toxicity is significant. Toxicity occurs due to irradiation of surrounding normal tissue. Current radiotherapy requires the addition of large planning margins to the radiation field to ensure target coverage regardless of the considerable organ motion in the pelvic region.
8p
vishanshan
27-06-2024
1
1
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Biliary tract cancer (BTC) is a relatively rare but aggressive gastrointestinal cancer with a high mortality rate. Cancer stem cell (CSC) populations play crucial roles in tumor biology and are responsible for the low response to anti-cancer treatment and the high recurrence rate. This study investigated the role of Transgelin-2 (TAGLN2), overexpressed in CSC in BTC cells, and analyzed its expression in patient tissues and serum to identify potential new targets for BTC.
15p
vishanshan
27-06-2024
1
1
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CRC with liver metastases is a major contributor to cancer-related mortality. Despite advancements in liver resection techniques, patient survival remains a concern due to high recurrence rates. This study seeks to uncover prognostic biomarkers that predict overall survival in patients undergoing curative hepatic resection for CRC liver metastases.
9p
vishanshan
27-06-2024
3
1
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Despite efforts to enhance the quality of medication prescribing in outpatient settings, potentially inappropriate prescribing remains common, particularly in unscheduled settings where patients can present with infectious and pain-related complaints. Two of the most commonly prescribed medication classes in outpatient settings with frequent rates of potentially inappropriate prescribing include antibiotics and nonsteroidal anti-infammatory drugs (NSAIDs).
12p
vishanshan
27-06-2024
1
1
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Disparities in rates of contraceptive use are frequently attributed to unequal access to and affordability of care. There is a need to better understand whether common definitions of affordability that solely relate to cost or to insurance status capture the reality of individuals’ lived experiences.
13p
vishanshan
27-06-2024
1
1
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Despite recent improvements in cancer detection and survival rates, managing cancer-related pain remains a significant challenge. The objective of this work was to select a panel of biomarkers of central pain processing and modulation and assess their ability to predict chronic pain in patients with cancer using predictive artificial intelligence (AI) algorithms.
11p
vikoch
27-06-2024
1
1
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While immunotherapy combined with chemotherapy (Chemo-IO) is generally recognized for providing superior outcomes compared to monotherapy (mono-IO), it is associated with a higher incidence of treatmentrelated adverse events (TRAEs), which may lead to treatment discontinuation. In this study, we compared the rates of treatment discontinuation between mono-IO and Chemo-IO as first-line treatments for various solid tumors.
12p
vikoch
27-06-2024
2
1
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Central nervous system (CNS) tumors are the most common solid tumors in children and the leading cause of cancer-related death in the latter. Currently, the incidence rate exceeds that of leukemia and ranks first in the incidence of malignant tumors in children.
10p
vikoch
27-06-2024
1
1
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There are limited and no standard therapies for recurrent glioblastoma. We herein report the antitumour activity and safety of sintilimab, bevacizumab and temozolomide (TMZ) in recurrent glioblastoma.
10p
vikoch
27-06-2024
1
1
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For the seventh time in the ten years the working group has existed people from different parts of the world gathered to discuss issues related to the Transfer and Diffusion of Information Technology. The theme of the 10th anniversary IFIP 8.6 working group event was “The Diffusion and Adoption of Networked Information Technologies”. Once again researchers and practitioners met and discussed if and how we can understand and model diffusion and adoption of technological innovations. The conference attracted 23 submissions.
232p
zizaybay1103
29-05-2024
5
1
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The paper presents a model for determining the significance of relations with the insurance company’s shareholders. The first hypothesis concerns the possibility to describe the relative importance of the resource supplied by each stakeholder, and its place in the ranked series. At the same time, the authors propose such a series both for a developing regional company and for a developed federal insurer. Such a series should correspond to the ranked series of growth rates of payment for each resource acquired from the corresponding stakeholder.
18p
longtimenosee10
26-04-2024
2
1
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At the present stage of the development of the world economy, suppl chain globalization is deepening the process of intertwining the national economies of the developed and developing world, reducing economic barriers to the cross-border movement of finances, goods, capital, and services, thereby facilitating their access to foreign markets.
6p
longtimenosee10
26-04-2024
4
1
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In the present paper we analyse the school performance of the Moroccan secondary students in the municipality of Collado Villalba (Northern Madrid region). For this aim we discuss several socio-economic parameters such as the evolution of unemployment, vegetative growth or immigration rate, etc., that are related to school performance and perspectives in general.
6p
viarnault
25-04-2024
5
1
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“SKD-61 steel finds extensive application in various sectors, including the marine industry where materials must withstand harsh aquatic conditions. In this study, we employ the Grey-Taguchi approach to optimize surface roughness (Ra), cutting force (Fc), and material removal rate (MRR) when hard-milling SKD-61 steel in pure minimum quantity lubrication (MQL) and nanofluid MQL environments, aligning with the demands of marine engineering
5p
vijaychest
24-04-2024
3
2
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The objective of this paper was to determine the criteria for selection of C-Check maintenance service provider for a Thai-Singaporean low cost airline. To identify the significant criteria, the documentary studies from reviewing ten related researches in scholarly literatures were conducted and then developed the semi-structure interview guide.
8p
longtimenosee07
29-03-2024
4
2
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Ebook "Crystallization and growth of colloidal nanocrystals" provides a current understanding of the mechanisms related to nucleation and growth for use in controlling nanocrystal morphology and physical-chemical properties, and is essential reading for any chemist or materials scientist with an interest in using nanocrystals as building blocks for larger structures. This book provides a compendium for the expert reader as well as an excellent introduction for advanced undergraduate and graduate students seeking a gateway into this dynamic area of research.
101p
coduathanh1122
27-03-2024
3
1
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