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Renal impairment
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Bone metastases are frequently observed in advanced cancer, and bone modifying agents are used to prevent or treat skeletal-related events. Zoledronic acid is contraindicated in patients with severe renal impairment (Ccr
8p
vikoch
27-06-2024
2
1
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Ebook "Blood pressure and arterial wall mechanics in cardiovascular diseases" are related to blood pressure involving two different and complementary aspects: the role of arterial wall mechanics and the underlying mechanisms of risk involving left ventricular hypertrophy and the role of dietary salt excess on the development of cardiac and renal failure through structural and functional impairment.
563p
manmanthanhla0201
27-02-2024
2
1
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Infections have been recognized as an uncommon cause of rhabdomyolysis, with evidence indicating a worse prognosis when compared to rhabdomyolysis caused by other etiologies. Diseases caused by Legionella pneumophila can present variably, ranging from mild to severe illness, as is sometimes the case with pneumonia.
5p
vitiki
30-01-2024
3
2
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Ebook "Studies on renal disorders" collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity.
781p
tachieuhoa
28-01-2024
8
2
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First-line treatment of nonsquamous non–small cell lung cancer (NSCLC) has undergone a paradigm shift to platinum combination therapy together with immune checkpoint inhibitors (ICIs). However, phase III studies of combinations of cytotoxic chemotherapy and ICIs have included only patients with maintained organ function, not those with renal impairment.
5p
vialfrednobel
23-12-2023
9
3
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Oral semaglutide is the only orally available GLP-1 receptor agonist. To achieve adequate bioavailability after oral administration, co-formulation with an absorption enhancer is needed.
5p
viporsche
28-10-2022
11
2
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In ICU patients, glomerular filtration is often impaired, but also supraphysiological values are observed (“augmented renal clearance”, >130 mL/min/1.73 m2 ). Renally eliminated drugs (e.g. many antibiotics) must be adjusted accordingly, which requires a quantitative measure of renal function throughout all the range of clinically encountered values.
8p
viisaacnewton
25-04-2022
11
1
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Nutritional deficiencies, renal impairment and chronic inflammation are commonly mentioned determinants of anaemia. The aim of this study was to investigate the effects of these determinants, singly and in combination, on anaemia in the very old.
11p
vinobelprisen
26-03-2022
20
4
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Acute kidney injury (AKI) is associated with high morbidity and mortality in dogs, but diagnosis may be impaired due the insensitivity of routine renal function biomarkers to detect earlier or milder forms of injury. Snake envenomation is one of several causes of AKI in dogs and humans.
13p
vidarwin
23-02-2022
16
1
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Acute kidney injury (AKI) is strongly associated with high morbidity and mortality of critically ill patients. In the last years several different biological markers with higher sensitivity and specificity for the occurrence of renal impairment have been developed in order to promptly recognize and treat AKI.
7p
vizhangzhidong
29-12-2021
19
0
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Mesangial cells play an important role in the glomerulus to provide mechanical support and maintaine efficient ultrafiltration of renal plasma. Loss of mesangial cells due to pathologic conditions may lead to impaired renal function.
14p
vijeeni2711
24-07-2021
6
0
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The reversible posterior leukoencephalopathy syndrome is a clinical/radiological syndrome characterized by headache, seizures, impaired vision, acute hypertension, and typical magnetic resonance imaging findings. There are several reports in the literature that depict its occurrence in cancer patients.
5p
viirene2711
03-10-2020
11
1
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Everolimus was recently introduced as a second-line treatment for renal cell carcinoma (RCC) and many other cancers. Several prospective studies have shown that serum creatinine levels are increased in a significant proportion of patients receiving everolimus.
7p
vilisa271
22-09-2020
15
1
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Bartter syndrome subtypes are a group of rare renal tubular diseases characterized by impaired salt reabsorption in the tubule, specifically the thick ascending limb of Henle’s loop.
6p
vimanama2711
28-07-2020
7
2
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Renal impairment (RI) is a negative prognostic factor in Multiple Myeloma (MM) and affected patients are often excluded from autologous stem cell transplantation (ASCT). However, it remains unclear whether historically inferior outcome data still hold true.
11p
vimanila2711
25-06-2020
9
0
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Incidence of renal dysfunction and risks of progression to end-stage renal disease (ESRD) were reported higher in upper urinary tract urothelial carcinoma (UTUC) than in renal cell carcinoma (RCC) patients after unilateral nephrectomy.
10p
viputrajaya2711
22-06-2020
9
1
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Patients with metastatic renal carcinoma frequently have pre-existing renal impairment and not infrequently develop worsening renal function as a complication of their treatment. The presence of pancreatic metastases in patients with metastatic renal carcinoma, often confers a more favourable prognosis and as a consequence this patient group may be exposed to such treatments for more prolonged periods of time.
6p
vikuala271
13-06-2020
5
1
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Bone complications (pathologic fracture, spinal cord compression, surgery to bone and radiation to bone) are a common problem in patients with multiple myeloma (MM). We set out to provide insights into the real-world burden of bone complications in patients with newly diagnosed MM (NDMM).
13p
vijakarta2711
09-06-2020
16
1
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Fats are regarded as crucial component of a balanced diet in dog as they help to maintain healthy skin coat, cell structure and function, including vision and learning abilities in addition to enhance taste and palatability of food. Omega-3 fatty acids are polyunsaturated fatty acids which are considered as essential fatty acids in dogs because they cannot be synthesized in the body and hence must be provided in the diet.
11p
caygaocaolon4
04-04-2020
23
0
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Dosing of antibiotics in critically ill patients is challenging. It becomes even more difficult if renal or hepatic impairment ensue. Modern means of renal replacement therapy are capable of removing antibiotics to a higher rate than decades ago, leaving clinicians with a high degree of uncertainty concerning the dose of antibiotics in this patient population.
5p
vienzym2711
03-04-2020
9
1
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