RNA polymerase
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Ebook "RNA metabolism and Gene expression in Archaea" focuses on the regulation of transcription and translation in Archaea; summarizes recent advances in our understanding of RNA metabolism in Archaea at all levels; provides a panoramic view of enzymes, machines and pathways used to synthesize, modify and break down RNA in Archaea; highlights the advantage of using Archaea as model organisms to study fundamental molecular mechanisms across the three domains of life;...
276p lucchinguyen 28-12-2023 3 2 Download
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Cervical cancer (CC) is a common gynecological malignancy worldwide. Some patients perform serious resistance after chemotherapy, and long-stranded non-coding RNA MEG3 is reported to be involved in the regulation of chemoresistance in many solid tumors. However, its involvement in cervical adenocarcinoma has not been reported.
13p vileonardodavinci 23-12-2023 4 3 Download
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The research focuses on the composition of a hard capsule formula containing the extracts of Houttuynia cordata, Morus alba, and Carica papaya as well as the development of testing standards for prepared hard capsules.
9p vispacex 16-11-2023 4 2 Download
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Polymerase I and transcript release factor (PTRF) plays a role in the regulation of gene expression and the release of RNA transcripts during transcription, which have been associated with various human diseases.
13p visharma 20-10-2023 2 2 Download
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Endometrial cancer (EC) arises from uterine endometrium tissue and is the most prevalent cancer of the female reproductive tract in developed countries. It has been predicted that the global prevalence of EC will increase in part because of its positive association with economic growth and lifestyle.
15p visharma 20-10-2023 2 2 Download
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Part 1 book "RT-PCR Protocols" includes content: Single cell RT-PCR on mouse embryos - A general approach for developmental biology; detection of influenza a virus neuraminidase and pb2 gene segments by one step reverse transcription polymerase chain reaction; RT-PCR amplification and cloning of large viral sequences,... and other contens.
189p oursky05 20-09-2023 1 0 Download
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Part 2 book "RT-PCR Protocols" includes content: Changes in gene expression of caveolin-1-after inflammatory pain using quantitative real time PCR; real time quantitative reverse transcriptase polymerase chain reaction; hot start PCR; primer design for RT-PCR,... and other contens.
150p oursky05 20-09-2023 1 0 Download
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Stathmin1 (STMN1) has been proposed as a possible prognostic marker and a potential therapeutic target for some cancers. We aimed to analyze the changes in autophagy, invasion, apoptosis-related genes in prostate cancer (PCa) cell line (PC-3), after small interfering RNA (siRNA)-mediated STMN1 silencing, and also the relationships of STMN1 expression, clinicopathological parameters, and survival (OS) in PCa cases.
12p lyhuyenthu 31-01-2023 7 2 Download
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This study aims to study PASD1 protein as a potential target for CRC immunotherapy. A total of 90 CRC and polyps tissue samples were investigated for PASD1 RNA and protein expression using a real-time polymerase chain reaction and immunohistochemical staining, respectively. Matched patients’ peripheral blood mononuclear cells were pulsed with PASD1 peptides and measured for immunogenicity, cell cytotoxicity, and cytokine assays.
17p lyhuyenthu 31-01-2023 5 2 Download
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In this study, we investigated the protection of EGCG for DNA single strand breaks in irradiated cells using primers for amplification of RNA polymerase, an enzyme responsible to synthesis of mRNA from the damaged DNA, through its down-regulated capacity.
4p vidumbledore 06-01-2023 7 2 Download
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Exosomes play a key role in cell-to-cell communication and are integral component of the tumor microenvironment. Recent observations suggest transfer of RNA through tumor-derived exosomes that can potentially translate into regulatory proteins in the recipient cells.
16p vikolindagrabar 27-07-2022 4 1 Download
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Accumulating evidence indicates that long non-coding RNAs (lncRNAs) are involving in the tumorigenesis and metastasis of lung cancer. The aim of the study is to systematically characterize the lncRNA-associated competing endogenous RNA (ceRNA) network and identify key lncRNAs in the development of stage I lung adenocarcinoma (LUAD).
12p vikolindagrabar 27-07-2022 6 2 Download
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Reportedly, circular RNA (circRNA) is a key modulator in the development of human malignancies. This work is aimed to probe the expression pattern, biological effects and mechanism of circ_0064288 on hepatocellular carcinoma (HCC) progression.
11p vikolindagrabar 27-07-2022 3 1 Download
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Co-transcriptional R-loops are abundant non-B DNA structures in mammalian genomes. DNA Topoisomerase I (Top1) is often thought to regulate R-loop formation owing to its ability to resolve both positive and negative supercoils. How Top1 regulates R-loop structures at a global level is unknown.
18p vigalileogalilei 27-02-2022 11 1 Download
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Alternative DNA secondary structures can arise from single-stranded DNA when duplex DNA is unwound during DNA processes such as transcription, resulting in the regulation or perturbation of these processes. We identify sites of high propensity to form stable DNA secondary structure across the human genome using Mfold and ViennaRNA programs with parameters for analyzing DNA.
19p vigalileogalilei 27-02-2022 11 1 Download
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Altering the biochemical makeup of chromatin by the incorporation of histone variants during development represents a key mechanism in regulating gene expression. The histone variant H2A.B, H2A.B.3 in mice, appeared late in evolution and is most highly expressed in the testis.
16p vigalileogalilei 27-02-2022 12 1 Download
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Canine distemper virus (CDV) is an enveloped negative-strand RNA virus that exhibits a high mutation rate and continuously expands the range of hosts. Notably, CDV has infected giant panda with spill over from viral reservoirs in canines.
9p vidarwin 23-02-2022 10 1 Download
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Apart from the huge worldwide economic losses often occasioned by bovine coronavirus (BCoV) to the livestock industry, particularly with respect to cattle rearing, continuous surveillance of the virus in cattle and small ruminants is essential in monitoring variations in the virus that could enhance host switching.
7p vigandhi 23-02-2022 8 1 Download
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Retrotransposons play a central role in plant evolution and could be a powerful endogenous source of genetic and epigenetic variability for crop breeding. To ensure genome integrity several silencing mechanisms have evolved to repress retrotransposon mobility.
10p vialfrednobel 29-01-2022 10 0 Download
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The human genome is hierarchically organized into local and long-range structures that help shape cell-type-specific transcription patterns. Transfer RNA (tRNA) genes (tDNAs), which are transcribed by RNA polymerase III (RNAPIII) and encode RNA molecules responsible for translation, are dispersed throughout the genome and, in many cases, linearly organized into genomic clusters with other tDNAs.
18p vialfrednobel 29-01-2022 6 0 Download