Schizophrenia

The serotonin neurotransmitter (5-HT) and its receptors have important roles in neuropsychiatric disorders such as schizophrenia. The aim of this study was to investigate the functional sequences of the 5′ regulation region of the human HTR1A gene to explore the effects on the expression of the 5-HT1A receptor.

9p vihagrid 30-01-2023 2 2   Download

(BQ) Ebook Brain, behavior and epigenetics: Part 1 presents the following content: Chapter 1: Posttranslational Histone Modifications and the Neurobiology of Psychosis; Chapter 2: Epigenetic Regulation of GABAergic Targets in Psychiatry; Chapter 3: Possible Roles of DNA Methylation in Bipolar Disorder; Chapter 4: The Epigenetics of Depression and Suicide; Chapter 5: Epidemiology Research and Epigenetics: Translational Epidemiology of Schizophrenia; Chapter 6: Environmental Studies as a Tool for Detecting Epigenetic Mechanisms in Schizophrenia; Chapter 7: Imprinting, Inactivation and the Beh...

160p runordie7 30-08-2022 6 1   Download

The importance of cell type-specific epigenetic variation of non-coding regions in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are conspicuously lacking.

21p vigalileogalilei 27-02-2022 7 1   Download

A coursebook: Exploring Pragmatics - Part 2 has present the content incitement in legal discourse; verbal irony; a pragmatic model of verbal parody; threats and impoliteness; speech act stage metaphor; pragmatics and behavioral game theory; clinical pragmatics revisited; pragmatic disorders in schizophrenia;...

268p chenlinong_0310 23-02-2022 10 1   Download

Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic psychosis and altered cognitive function. Despite success in identifying genetic variants associated with schizophrenia, there remains uncertainty about the causal genes involved in disease pathogenesis and how their function is regulated.

16p viaristotle 29-01-2022 4 0   Download

Autism spectrum disorder (ASD) is a common neurodevelopmental disorder that tends to co-occur with other diseases, including asthma, inflammatory bowel disease, infections, cerebral palsy, dilated cardiomyopathy, muscular dystrophy, and schizophrenia. However, the molecular basis of this co-occurrence, and whether it is due to a shared component that influences both pathophysiology and environmental triggering of illness, has not been elucidated.

19p viaristotle 29-01-2022 30 0   Download

Purpose of study is revealing significant differences in serum proteomes in schizophrenia and bipolar disorder (BD). Results: Quantitative mass-spectrometry based proteomic analysis was used to quantify proteins in the blood serum samples after the depletion of six major blood proteins.

14p visilicon2711 20-08-2021 14 0   Download

Genetic variations in brain-derived neurotrophic factor (BDNF) are associated with various psychiatric disorders including depression, obsessive-compulsive disorder, substance use disorders, and schizophrenia; altered gene expression triggered by these genetic variants may serve to create these phenotypes.

11p vilichoo2711 23-06-2021 4 0   Download

The following purposes: Determining characteristics of brain morphology using MRI images in schizophrenia in Vietnamese patients. Determining polymorphic variants of DISC1 and COMT genes in schizophrenia in Vietnamese patients.

27p petsematary 02-06-2021 10 0   Download

Schizophrenia is a severe brain disorder, and SNPs (Single nucleotide polymorphism) in schizophrenia-associated miRNAs are believed to be one of the important reasons for dysregulation which might contribute to the altered expression of genes and ultimately result in the disease.

9p vikentucky2711 26-11-2020 6 1   Download

Common and complex traits are the consequence of the interaction and regulation of multiple genes simultaneously, therefore characterizing the intercon‑ nectivity of genes is essential to unravel the underlying biological networks.

19p vicolorado2711 22-10-2020 9 0   Download

To describe EEG and relationship between EEG and clinical features in patients with schizophrenia. To assess the frequency of allele and genotypic distribution of ZNF804A gene polymorphism rs1344706 and COMT gene polymorphism rs165599 in patients with schizophrenia.

37p cothumenhmong6 17-07-2020 16 0   Download

(BQ) Subsequent chapters address specific psychological disorders and neurodegenerative diseases, including major depressive and bipolar disorders, anxiety, schizophrenia, disorders of childhood origin, and addiction, as well as neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. This highly readable textbook expands case examples and illustrations to discuss the latest research findings in clinical neuroscience from an empirical, interdisciplinary perspective.

288p nanhankhuoctai5 01-06-2020 11 1   Download

There is evidence that atypical antipsychotics (APs) increase risk of osteoporosis in schizophrenia patients, however the mechanism is unclear. The aim of the study was to explore the molecular mechanisms about Wnt/β-catenin signal pathway underlying the osteal side effects of APs.

10p vimax2711 30-03-2020 10 1   Download

The presentation of schizophrenia (SCH) symptoms differs between the sexes. Long-term treatment with antipsychotics is frequently associated with decreased bone mineral density, increased fracture risk and metabolic side effects. Perinatal phencyclidine (PCP) administration to rodents represents an animal model of SCH.

17p vimax2711 30-03-2020 11 0   Download

Second-generation antipsychotics are commonly prescribed for pediatric patients with schizophrenia and schizophrenia spectrum disorders despite their lack of approval for use in children. Although considered a safer alternative to first-generation antipsychotics, there is evidence to suggest that second-generation antipsychotics may be associated with some adverse events as well as an increase in prolactin levels.

14p videshiki2711 21-02-2020 8 0   Download

Data on the long-term efficacy, safety, and tolerability of risperidone in adolescents with schizophrenia are limited. The objective of this study was to evaluate the efficacy and safety of maintenance risperidone treatment in adolescents with schizophrenia.

15p viamsterdam2711 07-01-2020 12 2   Download

Youth with serious mental illness may experience improved psychiatric stability with second generation antipsychotic (SGA) medication treatment, but unfortunately may also experience unhealthy weight gain adverse events. Research on weight loss strategies for youth who require ongoing antipsychotic treatment is quite limited.

14p vilisbon2711 07-01-2020 8 1   Download

Catatonia has been associated with both schizophrenia and pervasive developmental disorders. The aim of this study was to evaluate catatonic features among adolescents suffering from schizophrenia. Further, we compared these features between adolescents with a comorbid pervasive developmental disorder and those without one.

7p vilisbon2711 07-01-2020 14 2   Download

Childhood abuse has been implicated as an environmental factor that increases the risk for developing schizophrenia. A recent large population-based case–control study found that abuse may be a risk factor for schizophrenia in women, but not men. Given the sex differences in onset and clinical course of schizophrenia, we hypothesized that childhood abuse may cause phenotypic differences in the disorder between men and women.

7p vimoskva2711 30-12-2019 16 0   Download