![](images/graphics/blank.gif)
Substituted aldehyde
-
The efficient synthesis of 12-substituted-3,4,4a,5,12,12a-hexahydrobenzo[b]acridine-1,6,11(2H)-triones starting from 2-amino-1,4-naphthoquinone, 1,3-cyclohexanedione, and different (hetero)aromatic aldehydes was developed. These reactions were carried out in acetic acid under microwave irradiation in the presence of p-toluenesulfonic acid as catalyst. The structure of the newly synthesized compounds were confirmed employing spectroscopic data as well as elemental analysis. The plausible mechanism of these three-component domino reactions was also described.
7p
dianmotminh02
03-05-2024
4
1
Download
-
Imidazole derivatives are one of the most important classes of nitrogen-containing five-membered heterocycles with a wide range of biological activities. Thus, the synthesis of these heterocycles has attracted intensive research interest.
8p
vidudley
20-02-2023
5
2
Download
-
Ionic liquid mediated synthesis of novel heterocyclic compounds 1-[(1H -benzoimidazol-2-yl)amino]-2 - phenylspiro[azetidine-4,4 -[4 H ]chroman]-2-ones (3) and 1-[(1H -benzoimidazol-2-yl)amino]-3-chloro-2 -phenylspiro[aze tidine-4,4 -[4 H ] chroman]-2-ones (4) was accomplished by condensing substituted 2-hydrazino benzimidazole (1), flavanone (2), and acetyl chloride/chloroacetyl chloride in ionic liquid, [bmim]PF6 with or without using catalyst in excellent yield (90%–95%).
13p
langthannam
29-12-2021
10
0
Download
-
A convenient and efficient method has emerged for the one-pot synthesis of substituted quinazolin-4(3H)- ones and nonaromatic alkaloids. 2-Substituted quinazolin-4(3H)-ones, 2,3-disubstituted quinazolin-4(3H)-ones, and 2,3-dihydroquinazolin-4(1H)-ones were obtained at yields of 46% to 95% by a one-pot reaction of N -(2-aminobenzoyl) benzotriazoles with amines and orthoesters or aldehydes under catalyst-free conditions.
47p
tudichquannguyet
29-11-2021
5
0
Download
-
This work involves a facile synthesis of three (S)-proline-based organocatalysts with C2 symmetry and their effects in enantioselective aldol reaction of acetone with substituted aromatic aldehydes. Moderate enantioselectivities (up to 61% ee) were obtained depending on the nature of the substituents on the aryl ring. Computational calculations at HF/6-31 + G(d) level were employed to underline the enantioselectivity imposed by all the organocatalysts.
58p
tudichquannguyet
29-11-2021
7
1
Download
-
Artificially fabricated hydroxyapatite (HAP) shows excellent biocompatibility with various kinds of cells and tissues which makes it an ideal candidate for a bone substitute material. In this study, hydroxyapatite nanoparticles have been prepared by using the wet chemical precipitation method using calcium nitrate tetra-hydrate [Ca(NO3)2.4H2O] and di-ammonium hydrogen phosphate [(NH4)2HPO4] as precursors. The composite scaffolds have been prepared by a freeze-drying method with hydroxyapatite, chitosan, and gelatin which form a 3D network of interconnected pores.
17p
tudichquannguyet
29-11-2021
11
1
Download
-
In continuation of our work, new diazenyl chalcones scafolds (C-18 to C-27) were efciently synthesized from substituted acetophenone azo dyes (A–E) by base catalyzed Claisen–Schmidt condensation with different substituted aromatic/heteroaromatic aldehydes.
19p
vijiraiya2711
27-05-2020
5
1
Download
-
Design, synthesis and biological potentials of novel tetrahydroimidazo[1,2-a] pyrimidine derivatives
A novel series of 5-(substituted aldehyde)-7-methyl-3-oxo-N-phenyl-2-((3,4,5,6-tetrahydroxytetrahydro2H-pyran-2-yl)methylene)-1,2,3,5-tetrahydroimidazo[1,2-a]pyrimidine-6-carboxamide analogues (1–24) was synthesized using the Biginelli condensation.
11p
vijiraiya2711
27-05-2020
15
1
Download
-
An effective and expeditious method of the synthesis of a highly functionalized piperidines, catalyzed by nontoxic, recyclable and environment friendly sodium lauryl sulfate (SLS), via one-pot multi-component condensation of aldehydes, amines and β-ketoesters in water at room temperature, has been developed.
8p
tocectocec
25-05-2020
9
2
Download
-
Synthesis of 1, 2-disubstituted benzimidazoles by reaction of N-substituted benzene-1,2-diamine with different aldehydes was developed. This greener procedure proceeds with the help of oxygen in water at 60oC. The advantages of proposed method are catalyst-free conditions in water, short reaction time and excellent yields.
8p
tocectocec
25-05-2020
8
0
Download
-
An efficient, three-component, catalyst free synthesis of dipyrazolo[1,5-a:3',4'-d]pyramid scaffolds has been carried out using 3-methyl-1H-pyrazol-5(4H)-one (1), 5-amino pyarazole (2a-b) and substituted aromatic aldehydes.
10p
tocectocec
25-05-2020
9
0
Download
-
The reaction of 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (1) as a binucleophile with primary aromatic or heterocyclic amines and formaldehyde or aromatic (heterocyclic) aldehydes in a molar ratio (1:1:2) gave the pyrimido[4,5-d]pyrimidin-2,4-dione ring systems 2–5. Treatment of 1 with diamines and formalin in molar ratio (2:1:4) gave the bis-pyrimido[4,5-d]pyrimidin-2,4-diones 6–8. Furthermore, substituted pyrimido[4,5-d]pyrimidin-2,4-diones with uracil derivative 11 or spiro indole 16 were synthesized.
7p
kethamoi1
17-11-2019
16
1
Download
-
World population is expected to reach 9.7 billion by 2050, which makes a great challenge the achievement of food security. The use of urease inhibitors in agricultural practices has long been explored as one of the strategies to guarantee food supply in enough amounts. This is due to the fact that urea, one of the most used nitrogen (N) fertilizers worldwide, rapidly undergoes urease-driven hydrolysis on soil surface yielding up to 70% N losses to environment.
9p
trinhthamhodang1
14-11-2019
11
0
Download
-
Salicylic aldehyde-N(4)-(4-ethoxyanilinyl)thiosemicarbazone (H2L) was synthesized by condensation between salicylic aldehyde (SA) and N(4)-(4-ethoxyanilinyl)thiosemicarbazide (TSCZ) in presence of glacial acetic acid as a homogeneous catalyst in ethanol. As a result of analysis by the surface response based on Box – Hunter model with the confidence level of 95%, the expectable yield reached the highest point (around 68%) at 80oC for 10 minutes when approximately 1 mole of SA reacted to equivalently 1 mole of TSCZ.
11p
vithomasedison2711
15-08-2019
29
0
Download
-
the book updated material on infrared spectroscopy and nuclear magnetic resonance of amines, aldehydes/ketones, and carboxylic acid derivatives. updated information on dna sequencing (the process of determination of the precise sequence of nucleotides within a dna molecule) and dna synthesis.
465p
bautroibinhyen20
06-03-2017
53
3
Download
-
(bq) part 2 book "instant notes in organic chemistry" has contents: carbocation stabilization, electronic and steric effects, reduction and oxidation, aldehydes and ketones, elimination versus substitution, preparation of phenols,...and other contents.
191p
bautroibinhyen20
06-03-2017
46
6
Download
-
3-Methyl-branched fatty acids, as phytanic acid, undergo peroxisomala-oxidation in which they are shortened by 1 carbon atom. This process includes four steps: activation, 2-hydroxylation, thiamine pyrophosphate dependent cleavage and aldehyde dehydrogenation. The thiamine pyrophosphate dependence of the third step is unique in peroxisomal mammalian enzymology. Human pathology due to a deficient alpha-oxidation is mostly linked to mutations in the gene coding for the second enzyme of the sequence, phytanoyl-CoA hydroxylase....
9p
fptmusic
16-04-2013
36
1
Download
-
VOC concentrations in the belly space were measured during four sampling events. Adjusted belly concentrations were compared to average adjusted indoor concentrations (Table 3). Here the fractional differences were positive for all compounds. For a number of VOCs, these differences were substantial (2-butanone, less volatile aldehydes, alkane hyrdrocarbons, and aromatic hydrocarbons except styrene).
238p
ut_hai_can
29-12-2012
54
7
Download
-
Common names: carboxylic acid - “aldehyde” is substituted for “ic acid”. Lower priority than ester - “oxo” group. Derived names: alkyls + ketone. IUPAC names: hydrocarbon + one.
42p
3dagkhoa
28-10-2010
99
30
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)