Target recognition

In this article, we propose a generative model based on the adversarial network structure to enhance images for the RAD-DAR multi-target dataset. The results of comparisons and evaluations indicate that the images generated by the proposed method exhibit a high degree of similarity to the original images.

7p visergeyne 18-06-2024 2 0   Download

Ebook "Biocompatible graphene for bioanalytical applications" highlights the latest advances in the use of graphene and bio-compatible-material-decorated graphene to detect various targets (e.g. DNA, RNA, amino acids, peptides, proteins, enzymes, antigens, glucose, DA, AA, UA, ATP, NADH, gas, ions, etc.). It focuses on the specific interaction of these substances with graphene (or modified graphene) and the efficient transduction of the target recognition event into detectable signals via various techniques.

122p nhanphanguyet 28-01-2024 4 2   Download

Ebook "RNA activation" offers an essential guide to RNA activation (RNAa), an emerging and fascinating new field. RNAa is a small RNA-guided and Argonaute-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs (dsRNAs) induce target gene expression at the transcriptional level. It occurs primarily in the nucleus and can be mediated by artificially designed short duplex RNAs that target regulatory sequences (e.g., promoters, genes’ 3’ termini and enhancers) and naturally occurring small RNAs (e.g., miRNAs and C. elegans 22G-RNAs).

238p lucchinguyen 28-12-2023 4 2   Download

Ebook "How to succeed as a freelance translator" has become a go-to reference for beginning and experienced translators alike. The fully revised third edition includes nearly 250 pages of practical tips on writing a translation-targeted resume and cover letter, preparing a marketing plan, marketing your services to agencies and direct client, avoiding common pitfalls, and more!

133p tichhythan 17-08-2023 10 7   Download

Ebook "Reading for the Real World 3 (Second edition)" supplemental readings included with each passage explore a different area or issue related to the main passage; reading exercises designed to hone comprehension skills targeting recognition of main ideas, specific details, and implied information; activities also encourage reading, writing, and speaking skills; pre-reading and post-reading exercises reinforce vocabulary words encountered in the readings.

148p tichhythan 17-08-2023 11 9   Download

— In this article, a travelling wave antenna that covers the 2 to 4 GHz band for human movement recognition is proposed. It is composed of a waveguide structure with slots in order to generate radiating beams in different directions. This frequencyscanned antenna is used to determine the moving target based on the Micro-Doppler radar effect. Then frequency signature obtained from the scanned system provides the 2D radar image of the movement.

6p wangziyi_1307 26-04-2022 9 1   Download

The CRISPR/Cas9 system, composed of a single-guide RNA for target recognition and a Cas9 protein for DNA cleavage, has the potential to revolutionize agriculture as well as medicine. Even though extensive work has been done to improve the gene editing activity of CRISPR/Cas9, little is known about the regulation of this bacterial system in eukaryotic host cells, especially at the post-transcriptional level.

15p vigalileogalilei 27-02-2022 14 1   Download

Long noncoding enhancer RNAs (lnc-eRNAs) are a subset of stable eRNAs identified from annotated lncRNAs. They might act as enhancer activityrelated therapeutic targets in cancer. However, the underlying mechanism of epigenetic activation and their function in cancer initiation and progression remain largely unknown.

23p viarchimedes 26-01-2022 10 0   Download

AsCas12a and LbCas12a nucleases are reported to be promising tools for genome engineering with protospacer adjacent motif (PAM) TTTV as the optimal. However, the C-containing PAM (CTTV, TCTV, TTCV, etc.) recognition by Cas12a might induce extra off-target edits at these non-canonical PAM sites.

13p viarchimedes 26-01-2022 8 1   Download

The hybrid distribution, other than joint probability (or possibility) distribution, has a couple of special normalization requirements that are order-dependent with respective to ‘‘addition” operation over random variable and ‘‘max’ operation over fuzzy variable. The derived sigma-max inference is applied to target recognition

17p guernsey 28-12-2021 10 0   Download

Ebolavirus (EBOV) is responsible for one of the most fatal diseases encountered by mankind. Cellular T-cell responses have been implicated to be important in providing protection against the virus. Antigenic variation can result in viral escape from immune recognition. Mapping targets of immune responses among the sequence of viral proteins is, thus, an important first step towards understanding the immune responses to viral variants and can aid in the identification of vaccine targets.

13p vilarryellison 29-10-2021 15 1   Download

F-box proteins are substrate-recognition components of the Skp1-Rbx1-Cul1-F-box protein (SCF) ubiquitin ligases. By selectively targeting the key regulatory proteins or enzymes for ubiquitination and 26S proteasome mediated degradation, F-box proteins play diverse roles in plant growth/development and in the responses of plants to both environmental and endogenous signals.

16p viansan2711 30-07-2021 10 1   Download

This paper is devoted to the variant of synthesis of a radar recognition algorithm with the ability to meet reliability of decisions. The algorithm is based on the theory of sequential analysis in combination with flexible change in the level of the classification detail when the observation time cannot be increased. Compared with one-step algorithms, the proposed algorithm allows guaranteeing “the posteriori probability of decisions is not smaller than the set value”. The proposed algorithm can be used in radar target recognition systems.

9p cothumenhmong11 05-05-2021 13 1   Download

The paper is targeted to apply state-of-the-art algorithms to solve the problem of Traffic Sign Recognition. In doing so, the first solution is detect possible locations of traffic signs from input images. Then, the data used is to be classified, so that two main stages will be focused on, which are feature extraction and classification...

7p trinhthamhodang1218 18-03-2021 10 2   Download

Epidermal growth factor receptor (EGFR) signalling plays a major role in biological processes, including cell proliferation, differentiation and survival. Since the over-expression of EGFR causes human cancers, EGFR is an attractive drug target.

16p vikentucky2711 24-11-2020 14 1   Download

GmrSD is a modification-dependent restriction endonuclease that specifically targets and cleaves glucosylated hydroxymethylcytosine (glc-HMC) modified DNA. It is encoded either as two separate single-domain GmrS and GmrD proteins or as a single protein carrying both domains. Previous studies suggested that GmrS acts as endonuclease and NTPase whereas GmrD binds DNA.

16p vioklahoma2711 19-11-2020 9 0   Download

In biomedical text mining, named entity recognition (NER) is an important task used to extract information from biomedical articles. Previously proposed methods for NER are dictionary- or rule-based methods and machine learning approaches. However, these traditional approaches are heavily reliant on large-scale dictionaries, target-specific rules, or well-constructed corpora.

11p vicolorado2711 23-10-2020 15 0   Download

RNA binding proteins (RBPs) play a fundamental role in posttranscriptional control of gene expression. Different RBPs have oncogenic or tumor-suppressive functions on human cancers. RNPC1 belongs to the RNA recognition motif (RRM) family of RBPs, which could regulate expression of diverse targets by mRNA stability in human cancer cells.

13p virose2711 24-09-2020 9 0   Download

Aptamers have emerged as excellent molecular probes for cancer diagnosis and therapy. The aim of the current study was to determine the feasibility of using DNA aptamer cy-apt 20 developed by live cell-SELEX for detecting and targeting gastric cancer.

9p vilisa271 22-09-2020 11 1   Download

This article has targeted Small and Medium Enterprises (SMEs) to analyze its recognition toward the new concept of CSV compared with that of large enterprises, as well as the relationship between CSV, CSR and R&D.

9p murielnguyen 25-06-2020 43 1   Download