Underlying diseases

ASA classification has been applied all over the world in premedication. The 2019 Amended ASA-PS was modified by new definitions, approved examples, especially definition for emergent patients. In Vietnam, there has not any independent study on ASA- PS classification up to now. The addition of “E” denotes emergency surgery.

8p viakimichi 17-01-2025 2 2   Download

Pneumonia is a potentially fatal disease that greatly compromises the health of children. Utilizing laboratory tests is extremely beneficial in the diagnosis, monitoring, and prognosis determination of the condition. In the realm of pediatric pneumonia, effective diagnostic procedures include assessments for albumin levels and iron deficiency anemia.

7p vinara 11-01-2025 0 0   Download

Pneumonia is a very common disease in children, especially children under 5 years old, due to their immature immune system not being able to fight against environmental pathogens. Malnutrition affects the severity and outcome of pneumonia treatment.

8p vinara 11-01-2025 1 0   Download

Anxiety disorder is one of the issue that affects the patient's physical and mental health and reduces the effectiveness of treatment. At the moment, patients with underlying conditions, particularly those with hypertension, are more likely to experience anxiety problems. This lessens quality of life, accelerates disease progression, exacerbates illness symptoms, and decreases treatment compliance rates.

7p vinara 11-01-2025 0 0   Download

Describe the knowledge, attitudes, and practices of mothers with children under one year of age on post-vaccination care and some related factors in Quang Ngai City, Quang Ngai province, in 2023. Methods: A cross-sectional study, interviewing 345 mothers with children under 1-year-old in 08 communes and wards of Quang Ngai City, Quang Ngai province, from February to April 2023.

9p vihatake 06-01-2025 5 1   Download

In this study, we assessed the status of antibiotic resistance of H. pylori isolates to antimicrobial agents at Hospital of Hue University of Medicine and Pharmacy in Central Vietnam and identified the underlying molecular mechanisms related to tetracycline and amoxicillin resistance.

8p viharuno 03-01-2025 2 2   Download

Group B streptococcus (GBS) infections are still the leading cause of invasive infections in neonates, specically they also seriously cause mortality and morbidity with underlying diseases in adults. Curently, there are ten GBS serotypes (Ia, Ib, and II-IX) and the resistance characteristic of GBS is important to clinical treatment.

5p viharuno 03-01-2025 4 1   Download

Under-nutrition is still a major contributor to disease and poor growth in vulnerable populations. Prolonged undernutrition affects physical health, mental and social development of children and exacts a heavy cost to their families and society at large. To describe prevalence of picky eaters and nutritional status of children aged 1 to 5 and to find out the relationship between picky eating and nutritional status of children.

5p viuchiha 03-01-2025 4 1   Download

The plants are vigorous, dome shaped and compact. These guavas are cultivated across the Allahabad, Uttar Pradesh region in the northern belt of India. Apple guava is cultivated today on almost 1000 hectares of land mainly under Kaushambi and Kaurihar -II districts of Allahabad] . The fruit is known for its medical properties such that during the winter season because it neutralizes disease symptoms.

5p chauchaungayxua11 23-03-2021 32 3   Download

Transmissible spongiform encephalopathies (TSE) are fatal neuro-degenerative diseases of humans and animals. The underlying infectious agent, the prion, accumulates not only in the central ner-vous system (CNS) but also in secondary lymphoid organs. I will revisit the role of the immune system in peripheral prion pathogen-esis, while focusing on the mechanisms by which extraneural and extralymphatic prion infectivity develops.

64p fptmusic 11-04-2013 36 4   Download

The spontaneous acquisition of resistance to a variety of unrelated cytotoxic compounds has important implications in medical treatment of infectious diseases and anticancer therapy. In the yeast Saccharomyces cerevisiaethis pheno-menon is caused by overexpression of membrane efflux pumps and is called pleiotropic drug resistance. We have found that allelic forms of the genes for the transcription activators Pdr1p and Pdr3p, designated PDR1-12and PDR3-33,respectively, mediate resistance to diazaborine....

8p dell39 03-04-2013 38 3   Download

The biochemical nature and the replication of infectious prions have been intensively studied in recent years. Much less is known about the cellular events underlying neuronal dysfunction and cell death. As the cellular func-tion of the normal cellular isoform of prion protein is not exactly known, the impact of gain of toxic function or loss of function, or a combination of both, in prion pathology is still controversial.

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Antichymotrypsin, a member of the serpin superfamily, has been shown to form inactive polymers in vivo, leading to chronic obstructive pulmonary disease. At present, however, the molecular determinants underlying the polymerization transition are unclear.

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It has been well documented that both endogenous inflammatory mediator advanced glycation end products (AGEs) and exogenous inflammatory inducer lipopolysaccharide play key roles in the initiation and development of inflammatory diseases. However, the combined inflammation-stimulatory effect of AGEs and lipopolysaccharide on endothelial cells, and, further-more, the underlying signal transduction pathways involved, have not been fully elucidated.

9p vinaphone15 25-02-2013 32 2   Download

Alzheimer’s disease is characterized by neuropathological accumulations of amyloidb(1–42) [Ab(1–42)], a cleavage product of the amyloid precursor protein (APP). Recent studies have highlighted the role of APP in Ab-med-iated toxicity and have implicated the G-protein system; however, the exact mechanisms underlying this pathway are as yet undetermined.

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Heparanase is an endo-b-D-glucuronidase capable of cleaving heparan sul-fate side chains at a limited number of sites, yielding heparan sulfate frag-ments of still appreciable size. Importantly, heparanase activity correlates with the metastatic potential of tumor-derived cells, attributed to enhanced cell dissemination as a consequence of heparan sulfate cleavage and remod-eling of the extracellular matrix and basement membrane underlying epithe-lial and endothelial cells.

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Sialylated oligosaccharides, present on mammalian outer-cell surfaces, play vital roles in cellular interactions and some bacteria are able to mimic these structures to evade their host’s immune system. It would be of great benefit to the study of infectious and autoimmune diseases and cancers, to under-stand the pathway of sialylation in detail to enable the design and produc-tion of inhibitors and mimetics.

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Cerebral cavernous malformations (CCM) are common vascular malforma-tions with an unpredictable risk of hemorrhage, the consequences of which range from headache to stroke or death. Three genes, CCM1, CCM2and CCM3, have been linked to the disease. The encoded CCM proteins inter-act with each other within a large protein complex.

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MicroRNAs (miRNAs) are a class of small noncoding RNAs that have gained status as important regulators of gene expression. Recent studies have demonstrated that miRNAs are aberrantly expressed in the cardiovas-cular system under some pathological conditions.

15p cosis54 05-01-2013 44 5   Download

The molecular biology underlying protein aggregation and neuronal death in Alzheimer’s disease is not yet completely understood, but small soluble nonamyloid aggregates of the amyloidb-protein (Ab) have been shown to play a fundamental neurotoxic role.

9p cosis54 09-12-2012 43 3   Download