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Vascular endothelial growth factor
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Diabetic retinopathy (DR) is a dangerous microvascular complication of diabetes mellitus (DM). The escalating prevalence of diabetes increases the rate of DR patients in Vietnam. Numerous studies have indicated that serum vascular endothelial growth factor (VEGF) can be used as a marker for monitoring the progression of this disease.
9p
vikoch
27-06-2024
1
1
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Anlotinib is a multi-target tyrosine kinase inhibitor (TKI) targeting the vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), and c-Kit. This phase II study aimed to assess the efficacy and safety of anlotinib, either alone or in combination with bevacizumab (Bev) for recurrent high-grade glioma (rHGG) (NCT04822805, 30/03/2021).
11p
vishanshan
27-06-2024
2
1
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Anti-vascular endothelial growth factor monoclonal antibody (anti-VEGF) or immune checkpoint inhibitors (ICIs) combined with chemotherapy are commonly administered to cancer patients. Although cancer patients receiving anti-VEGF or ICIs have been reported to experience an increased risk of acute kidney injury (AKI), comparative studies on the AKI incidence have not been evaluated.
9p
vikoch
27-06-2024
1
1
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Resistance to immune checkpoint inhibitors (ICIs) represents a major unmet medical need in non-small cell lung cancer (NSCLC) patients. Vascular endothelial growth factor (VEGF) inhibition may reverse a suppressive microenvironment and recover sensitivity to subsequent ICIs.
10p
vikoch
27-06-2024
1
1
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Ebook "VEGF in development" is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for development and disease in vertebrates. VEGFA controls the proliferation, migration, specialisation and survival of vascular endothelial cells, and it is therefore essential for the establishment of a functional blood vessel circuit.
116p
tracanhphuonghoa1007
22-04-2024
4
2
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Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its receptor interaction, thus obstructing the formation of new blood vessels.
14p
vibransone
28-03-2024
4
2
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Part 1 book "Cancer immunology and immunotherapy" includes content: Immune infiltration in human cancer - prognostic significance and disease control, subversion and coercion - the art of redirecting tumor immune surveillance, a target to enhance antitumor immune response, biology and clinical observations of regulatory T-cells in cancer immunology, concepts and ways to amplify the antitumor immune response, angiogenesis and the tumor vasculature as antitumor immune modulators - The role of vascular endothelial growth factor and endothelin.
163p
muasambanhan08
23-02-2024
6
1
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Uveal effusion syndrome is a rare disease characterized by exudative detachments of the choroid, ciliary body, and retina. Various surgical procedures and nonsurgical strategies have been described to treat uveal effusion syndrome with limited success.
10p
vilazada
31-01-2024
3
2
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Pneumatosis intestinalis is a rare disease characterized by gas-flled cysts within the submucosa or serosa of the intestinal tract. In recent years, pneumatosis intestinalis was reported in patients undergoing cancer treatment, and some case reports exist that report that pneumatosis intestinalis occurs during administration of vascular endothelial growth factor inhibitors, such as bevacizumab and sunitinib.
5p
vilazada
31-01-2024
4
2
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In vivo antiangiogenic effect of nimbolide, trans-chalcone and piperine for use against glioblastoma
Angiogenesis is an important hallmark of Glioblastoma (GBM) marked by elevated vascular endothelial growth factor-A (VEGF-A) and its receptor 2 (VEGFR-2). As previously reported nimbolide (NBL), trans-chalcone (TC) and piperine (PPR) possess promising antiangiogenic activity in several cancers however, their comparative efcacy and mechanism of antiangiogenic activity in GBM against VEGFR-2 has not been elucidated.
21p
vileonardodavinci
23-12-2023
3
2
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Anti−vascular endothelial growth factors (VEGFs) treatment has been associated with an increased risk of thromboembolic events. Therefore, the use of anti−VEGFs for patients with colorectal cancers (CRC) has raised concerns about the potential risk of retinal vein occlusion (RVO), an ocular disease caused by embolism or venous stasis.
11p
visharma
20-10-2023
3
2
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Few studies have focused on the impact of single-organ pulmonary metastases on progression-free survival and overall survival in patients with metastatic colorectal cancer. Recognizing differences in prognosis and chemotherapeutic efficacy based on metastasized organs may help in optimizing treatment strategies.
10p
vioracle
29-09-2023
4
2
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Well-differentiated (WD) neuroendocrine tumors (NETs) are a group of rare neoplasms with limited therapeutic options. Cabozantinib is an inhibitor of multiple tyrosine kinases with a pivotal role in NET pathogenesis, including c-MET and Vascular Endothelial Growth Factor Receptor 2 (VEGFR2).
10p
vioracle
29-09-2023
8
2
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The selection of a wound dressing is crucial for successful wound management. Conventional dressings are preferable for the treatment of simple wounds. However, a bioactive wound dressing that supports wound management and accelerates the healing process is required when it comes to treating non-self-healing wounds. 2-deoxy-D-ribose (2dDR) is a small deoxy sugar that naturally occurs in human body.
16p
lyhuyenthu
31-01-2023
7
2
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Bài viết "Nghiên cứu sự thay đổi hàm lượng EGF, VEGF của bệnh nhân có vết thương mạn tính được điều trị bằng huyết tương giàu tiểu cầu" trình bày 2 nội dung: Đánh giá sự thay đổi hàm lượng EGF (epidermal growth factor) và VEGF (vascular endothelial growth factor) trong PRP trước và sau khi hoạt hóa; đánh giá sự thay đổi hàm lượng EGF, VEGF tại chỗ VTMT được điều trị bằng PRP.
11p
runthenight01
18-11-2022
11
3
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The microenvironment within solid malignant tumors, including feline mammary gland carcinomas (FMGCs), is commonly hypoxic, possibly due to the lack of functional blood vessels in rapidly proliferating neoplastic tissue.
10p
vigalileogalilei
28-02-2022
14
1
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Extreme panting under heat stress threatens dairy cattle milk production. Previous research has revealed that the gas exchange-mediated respiratory drive in critically ill dairy cattle with low O2 saturation induces panting. Vascular endothelial growth factor (VEGF) signaling may play important roles in immunosuppression and oxidative stress during severe respiratory stress responses in heat-stressed cattle.
14p
vidarwin
23-02-2022
15
1
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Rivoceranib, a novel tyrosine kinase inhibitor, exhibits anti-tumour effects by selectively blocking vascular endothelial growth factor receptor-2 (VEGFR2) in cancer cells. Recently, the therapeutic effects of rivoceranib on solid tumours have been elucidated in human patients.
12p
vidarwin
22-02-2022
10
1
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Vascular endothelial growth factor (VEGF) plays a role in the tumor microenvironment. Sorafenib, which inhibits the VEGF pathway, has an immune-modulation function but lacks substantial clinical data. This study aims to explore the efficacy of anti-PD-1 combined sorafenib in advanced hepatocellular carcinoma (HCC).
8p
vielonmusk
21-01-2022
14
0
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Extracorporeal membrane oxygenation (ECMO) is often used in critical patients with severe myocardial failure. However, the mortality rate of patients on ECMO is often high. Recent studies have suggested that endothelial activation with subsequent vascular barrier breakdown is a critical pathogenic mechanism of organ damage and is related to the outcome of critical illness.
8p
vizhangzhidong
29-12-2021
7
0
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