Whole numbers

Ebook "Pre algebra demystified: A self teaching guide" presents the basic topics in arithmetic and introductory algebra in a logical, easy-to-read format. This book can be used as an independent study course or as a supplement to a pre-algebra course. To learn mathematics, you must know the vocabulary, understand the rules and procedures, and be able to apply these rules and procedures to mathematical problems in order to solve them. This book is written in a style that will help you with learning. Important terms have been bold faced, and important rules and procedures have been italicized.

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In this study, we conducted sequencing of the entire gene coding region (WES) in the patient and identified a compound heterozygote variants (c.289C>G, p.Arg97Gly and c.433C>T, p.Arg145Trp) in the TNNI3 gene. These variants were inherited from the patient's father and mother, who were heterozygous variant carriers. These variants were also identified as the pathogenic variants in the ClinVar database (accession number VCV001331910.2 and VCV000012426.28, respectively) and were the cause of the patient's disease.

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The aim of this qualitative case study is to investigate prospective mathematics teachers’ subject matter knowledge of the underlying concepts of standard and nonstandard algorithms used to solve the problems with whole numbers. Twenty three prospective mathematics teachers enrolled in the Elementary Mathematics Education Program of one of the most successful universities in Turkey were the participants of the study.

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Ebook "Complement therapeutics" highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and sepsis.

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Ebook "Eco-immunology: Evolutive aspects and future perspectives" represents a cutting-edge contribution giving an all-around perspective of eco-immunology today. Beside questions of the utmost importance for the whole community of immunologists, e.g, the intrinsic limits of immunological experiments performed at the bench on a limited number of selected models, the book covers several other facets of the eco-immunological approach, including host-parasite interactions, human aging and population immunology.

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Since different types of genetic variants, from single nucleotide variants (SNVs) to large chromosomal rearrangements, underlie intellectual disability, we evaluated the use of whole-genome sequencing (WGS) rather than chromosomal microarray analysis (CMA) as a first-line genetic diagnostic test.

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Large numbers of autosomal sites are found differentially methylated in the aging genome. Due to analytical difficulties in dealing with sex differences in X-chromosome content and X-inactivation (XCI) in females, this has not been explored for the X chromosome.

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Unlocking clinically translatable genomic information, including copy number alterations (CNA), from formalin-fixed paraffin-embedded (FFPE) tissue is challenging due to low yields and degraded DNA. We describe a robust, cost-effective low-coverage whole genome sequencing (LC WGS) method for CNA detection using 5 ng of FFPE-derived DNA.

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Whole genome sequencing (WGS) has the potential to outperform clinical microarrays for the detection of structural variants (SV) including copy number variants (CNVs), but has been challenged by high false positive rates.

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Inflammatory breast cancer (IBC) has a highly invasive and metastatic phenotype. However, little is known about its genetic drivers. To address this, we report the largest cohort of whole-genome sequencing (WGS) of IBC cases.

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Single-cell genomics is a rapidly advancing field; however, most techniques are designed for mammalian cells. We present a single-cell sequencing pipeline for an intracellular parasite, Plasmodium falciparum, with a small genome of extreme base content.

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Metagenomic next-generation sequencing (mNGS) of body fluids is an emerging approach to identify occult pathogens in undiagnosed patients. We hypothesized that metagenomic testing can be simultaneously used to detect malignant neoplasms in addition to infectious pathogens.

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Recent studies have suggested that individual variants do not sufficiently explain the variable expressivity of phenotypes observed in complex disorders. For example, the 16p12.1 deletion is associated with developmental delay and neuropsychiatric features in affected individuals, but is inherited in > 90% of cases from a mildly-affected parent.

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Ebook "Electronic structure and number theory: Bohr’s boldest dream" is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed.

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Ebook "Orchid biology: Reviews and perspectives, X" aim is not to balance every volume, but to make a balanced and wide ranging presentation of orchids in the series as a whole. The chapters in this, the last volume of the series, range over a number of topics which were not covered before. Singapore is justly famed for its orchids. They can be seen on arrival (or dep-ture) in its modern, highly efficient and comfortable Changi Airport and on the way from it to town. Vanda Miss Joaquim, the first hybrid to come from Singapore became its National Flower.

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Streptococcus pneumoniae is a gram-positive opportunistic pathogen, and infection risks of S. pneumoniae can be profoundly augmented by its acquired multidrug-resistance (MDR). The rapid development of MDR in S. pneumoniae was attributed to the international dissemination of a small number of multidrug-resistant “clones.”

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Small and medium enterprises (SMEs), which make up over 90% of the total number of enterprises in Vietnam, play important roles in economic development not only in Hanoi but also in the whole country. As an effective tool in business management, accounting supplies important information for making decisions.

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Basic Math Skills is divided into the following sections, which correspond to the strands of the NCTM content standards: Number and Operations, Algebra, Geometry, Measurement, and Data Analysis and Probability. Each section includes a variety of reproducible pages that reinforce basic math skills taught at the fifth-grade level.

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Ebook Basic Math skills - Grade 6 is divided into the following sections, which correspond to the strands of the NCTM content standards: Number and Operations, Algebra, Geometry, Measurement, and Data Analysis and Probability. Each section includes a variety of reproducible pages that reinforce basic math skills taught at the sixth-grade level. These pages include: Games, puzzles, and mazes; drill and practice pages; problem solving and application practice; tests in standardized format.

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Using the Standards: Algebra - Grade 5 focuses on the National Council of Teachers of Mathematics (NCTM) content standards of Algebra. The activities are divided into four main sections, based on the NCTM Algebra standards. NCTM defines the standards as follows. Students will be able to represent and analyze mathematical situations and structures using algebraic symbols.

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