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Báo cáo khoa học: Amyloid oligomers: dynamics and toxicity in the cytosol and nucleus
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The accumulation of misfolded proteins in the cytosol and nucleus of neuronal cells leads to neurodegenerative disorders. Polyglutamine diseases are caused by polyglutamine-expanded proteins, whereas mutations in superoxide dismutase 1 lead to amyotrophic lateral sclerosis.
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