Báo cáo khoa học: Applications of diagonal chromatography for proteomewide characterization of protein modifications and activity-based analyses
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Numerous gel-free proteomics techniques have been reported over the past few years, introducing a move from proteins to peptides as bits of informa-tion in qualitative and quantitative proteome studies. Many shotgun pro-teomics techniques randomly sample thousands of peptides in a qualitative and quantitative manner but overlook the vast majority of protein modifi-cations that are often crucial for proper protein structure and function.
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