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Báo cáo khoa học: Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:15

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PKR is an interferon-induced serine-threonine protein kinase that plays an important role in the mediation of the antiviral and antiproliferative actions of interferons. PKR is present at low basal levels in cells and its expression is induced at the transcriptional level by interferons. PKR’s kin-ase activity stays latent until it binds to its activator. In the case of virally infected cells, double-stranded (ds) RNA serves as PKR’s activator.

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Nội dung Text: Báo cáo khoa học: Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR

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