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Báo cáo khoa học: In vivo heteromer formation. Expression of soluble bA4-crystallin requires coexpression of a heteromeric partner
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Theb-crystallins are a family of long-lived, abundant structural proteins that are coexpressed in the vertebrate lens. As b-crystallins form hetero-mers, a process that involves transient exposure of hydrophobic interfaces, we have examined whetherin vivo b-crystallin assembly is enhanced by pro-tein chaperones, either small heat shock proteins, Hsp27 or aB-crystallin, or Hsp70.
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