Báo cáo khóa học: Induction of endothelial apoptosis by 4-hydroxyhexenal
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Lipid peroxidation and its products such as 4-hydroxy-2-nonenal (HNE) and 4-hydroxyhexenal (HHE) are known to affect redox balance duringagingand various degenerative processes, includingvascular dysfunction. Deterioration of the endothelial cells that line the vascular wall is known to be an underlyingcause of vascular dysfunction. At present, little is known about themechanismbywhichHHE induces endothelial cell death (i.e. apoptosis), although HNE-induced apoptotic cell death has been reported. ...
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