Báo cáo khoa học: Kinetic analysis of zymogen autoactivation in the presence of a reversible inhibitor
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Limited proteolysis is a highly specific irreversible process, which can serve to initiate physiological function by con-verting a precursor protein into a biologically active form. When the activating enzyme and the activated enzyme coincide, the process is an autocatalytic zymogen activation (i.e. reactions inwhich the zymogens serves as a substrate for the corresponding active enzyme). The activity of proteases is frequently regulated by the binding of specific protease inhibitors.
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