Báo cáo khoa học: Mechanisms of amyloid fibril formation – focus on domain-swapping
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Conformational diseases constitute a group of heterologous disorders in which a constituent host protein undergoes changes in conformation, lead-ing to aggregation and deposition. To understand the molecular mecha-nisms of the process of amyloid fibril formation, numerousin vitro and in vivo studies, including model and pathologically relevant proteins, have been performed.
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