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Báo cáo khoa học: Membrane protein integration into the endoplasmic reticulum
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Most integral membrane proteins are targeted, inserted and assembled in the endoplasmic reticulum membrane. The sequential and potentially over-lapping events necessary for membrane protein integration take place at sites termed translocons, which comprise a specific set of membrane pro-teins acting in concert with ribosomes and, probably, molecular chaperones to ensure the success of the whole process.
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