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Báo cáo khoa học: Metabolic pathways leading from amino acids to vitamin B12 in Propionibacterium shermanii, and the sources of the seven methyl carbons
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The metabolic pathways leading froml-[2-13 C]aspartic acid, [2-13 C]glycine andl-[methyl-13 C]methionine to vitamin B12were investigated, focusing on the biosynthetic pathways leading to the aminopropanol moiety of vita-min B12and on the role of the Shemin pathway leading tod-aminolevulinic acid (a biosynthetic intermediate of tetrapyrrole), by means of feeding experiments with Propionibacterium shermaniiin combination with 13 C-NMR spectroscopy.
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