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Báo cáo khóa học: New activities of a catalytic antibody with a peroxidase activity

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

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In order to estimate the size of the cavity remaining around the heme of the 3A3–microperoxidase 8 (MP8) hemo-abzyme,the formation of 3A3–MP8–Fe(II)-nitrosoalkane complexes upon oxidation of N-monosubstituted hydroxyl-amines was examined. This constituted a new reaction for hemoabzymes and is the first example of fully characterized Fe(II)–metabolite complexes of antibody–porphyrin. Also, via a comparison of the reactions with N-substituted hyd-roxylamines of various size and hydrophobicity,antibody 3A3 was confirmed to bring about a partial steric hindrance on the distal face of MP8....

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Nội dung Text: Báo cáo khóa học: New activities of a catalytic antibody with a peroxidase activity

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