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Báo cáo khoa học: Properties and significance of apoFNR as a second form of air-inactivated [4Fe-4S]ÆFNR of Escherichia coli

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:10

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The active form of the oxygen sensor fumarate nitrate reductase regulator (FNR) of Escherichia colicontains a [4Fe-4S] cluster which is converted to a [2Fe-2S] cluster after reaction with air, resulting in inactivation of FNR. Reaction of reconstituted [4Fe-4S]ÆFNR with air resulted within 5 min in conversion to apoFNR. The rate was comparable to the rate known for [4Fe-4S]ÆFNR⁄[2Fe-2S]ÆFNR cluster conversion, suggesting that apoFNR is a product of [2Fe-2S]ÆFNR decomposition and a final form of air-inacti-vated FNR in vitro. ...

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Nội dung Text: Báo cáo khoa học: Properties and significance of apoFNR as a second form of air-inactivated [4Fe-4S]ÆFNR of Escherichia coli

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