Báo cáo khoa học: Simulation study of methemoglobin reduction in erythrocytes Differential contributions of two pathways to tolerance to oxidative stress
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Methemoglobin (metHb), an oxidized form of hemoglobin, is unable to bind and carry oxygen. Erythrocytes are continuously subjected to oxida-tive stress and nitrite exposure, which results in the spontaneous formation of metHb. To avoid the accumulation of metHb, reductive pathways medi-ated by cytochrome b5 or flavin,
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