intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:10

32
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

TheDrosophila melanogasterdeoxyribonucleoside kinase (Dm-dNK) double mutant N45D⁄N64D was identified during a previous directed evolution study. This mutant enzyme had a decreased activity towards the natural substrates and decreased feedback inhibition with dTTP, whereas the activ-ity with 3¢-modified nucleoside analogs like 3¢-azidothymidine (AZT) was nearly unchanged.

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
3=>0