Báo cáo khoa học: SUMOylation of the hepatoma-derived growth factor negatively influences its binding to chromatin
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Hepatoma-derived growth factor is a nuclear targeted mitogen containing a PWWP domain that mediates binding to DNA. To date, almost nothing is known about the molecular mechanisms of the functions of hepatoma-derived growth factor, its routes of secretion and internalization or post-translational modifications.
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