Báo cáo khoa học: The aggregation potential of human amylin determines its cytotoxicity towards islet b-cells
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Human amylin is a small fibrillogenic protein that is the major constituent of pancreatic islet amyloid, which occurs in most subjects with type 2 dia-betes. There is evidence that it can elicitin vitro apoptosis in isletb-cells, but the physical properties that underpin its cytotoxicity have not been clearly elucidated.
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