intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: The effect of HAMP domains on class IIIb adenylyl cyclases from Mycobacterium tuberculosis

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:6

36
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

The genesRv1318c, Rv1319c, Rv1320cand Rv3645 1 of Mycobacterium tuberculosisare predicted to code for four out of 15 adenylyl cyclases in this pathogen. The proteins consist of a membrane anchor, a HAMP region and a class IIIb adenylyl cyclase catalytic domain. Expression and purification of the isolated catalytic domains yielded aden-ylyl cyclase activity for all four recombinant proteins. Expression of the HAMP region fused to the catalytic domain increased activity in Rv3645 21-fold and slightly reduced activity in Rv1319c by 70%, demonstrating iso-form-specific effects of the HAMP domains. ...

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: The effect of HAMP domains on class IIIb adenylyl cyclases from Mycobacterium tuberculosis

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2