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Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:0

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Neurotransmitter transporters play a major role in achieving low concen-trations of their respective transmitter in the synaptic cleft. The GABA transporter GAT1 belongs to the family of Na + - and Cl – -coupled trans-port proteins which possess 12 putative transmembrane domains and three N-glycosylation sites in the extracellular loop between transmembrane domain 3 and 4.

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Nội dung Text: Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter

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