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Báo cáo Y học: Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:8

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Protein histidine phosphorylation in eukaryotes has been sparsely studied compared to protein serine/threonine and tyrosine phosphorylation. In an attempt to rectify this by probing porcine liver cytosol with the phosphohistidine-containing peptide succinyl-Ala-His(P)-Pro-Phe-p-nitro-anilide (phosphopeptide I), we observed a phosphatase activity that was insensitive towards okadaic acid and EDTA.

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Nội dung Text: Báo cáo Y học: Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase

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