Active ingredients

Medicines in the DPP4 inhibitor class include sitagliptin, saxagliptin, linagliptin, and alogliptin. However, research data on the mechanism of action of the active ingredients of WBG on DPP4 are also limited. Therefore, this in silico study aimed to idenfy acve ingredients with strong or potential effects on the DPP4 target for andiabec acvity of WBG.

8p viling 11-10-2024 4 1   Download

Amlodipine is a representative active ingredient of calcium channel blockers. In addition to the general advantages of calcium channel blockers in treating hypertension, amlodipine also effectively controls blood pressure for 24 hours and has no or just a little effect on neurohormonal activation, so it does not cause high blood pressure at the last dose. However, amlodipine has a plasma half-life of between 30 and 40 hours, slowing the drug's action duration.

9p viakimichi 17-01-2025 6 2   Download

Paracetamol is one of the most commonly used active ingredients, even without a doctor's prescription for most people. It has effects on relieving pain and treating fever, especially with an analgesic effect for the elderly who have to suffer from degenerative joint disease. However, the half-life of paracetamol is relatively short, from 1 to 3 hours, so patients need to use it many times a day.

9p vinara 11-01-2025 3 1   Download

Mango seeds (Mangiferin indica L.) have the ability to inhibit P. acnes, S. aureus, and E. coli bacteria and inhibit inflammation, potentially for transdermal therapeutic dosage forms. The nano-emulsion dosage forms were prepared based on the SNEDDS system with nano-oil droplets containing mango seed extract. These dosage forms contributed to carrying the active ingredient deeply into the impact site, bringing the highest efficiency, but this needs to be proven.

8p vinara 11-01-2025 1 1   Download

The study clarified the main chemical composition of the roots of F. multiflora. Studying and developing a process of qualitative and quantitative analysis of several active ingredients at the same time. Application of analytical procedure has established and evaluated the content of active ingredients in some F. multiflora medicinal samples. The research results are obtained as a scientific basis for further studies.

23p extraenglish 24-05-2021 28 2   Download

The genus Litsea Lam. (Lauraceae) and Lepisanthes Blume (Sapindaceae) are wildly distributed in Vietnam, especially in the mountainous areas. The reports in the literatures indicated that these two genus contain many constituents with interesting structures and potential biological activities. In order to find interesting substances for development of new pharmaceutical ingredients or functional food products we would like to conduct the resarch thesis ‘‘Study on Chemical constituents and biological activities of Litsea glutinosa (Lour.) Rob. (Lauraceae) and Lepisanthes rubiginosa (Roxb.

26p xacxuoc4321 11-07-2019 36 6   Download

Tất cả các sản phẩm OTC đều liệt kê liều dùng, những thông tin khuyến cáo để người tiêu dùng có thể lựa chọn và sử dụng đúng sản phẩm. Bạn sẽ tìm thấy những thông tin sau: - Hoạt chất (active ingredient): là những chất có tác dụng trị liệu, mục này liệt kê hàm lượng của hoạt chất có trong một đơn vị thuốc. - Công dụng (uses): Bệnh hoặc những triệu chứng mà sản phẩm sẽ điều trị hoặc ngăn ngừa. - Thận trọng: Khi nào không nên sử dụng thuốc, những tác dụng phụ có thể...

7p chupchupnp 19-06-2013 122 9   Download

Endovanilloids are defined as endogenous ligands of the transient receptor potential vanilloid type 1 (TRPV1) protein,a nonselective cation channel that belongs to the large family of TRP ion channels,and is activated by the pungent ingredient of hot chilli peppers,capsaicin. TRPV1 is expressed in some nociceptor efferent neurons, where it acts as a molecular sensor of noxious heat and low pH. However,the presence of these channels in var-ious regions of the central nervous system,where they are not likely to be targeted by these noxious stimuli,suggests the existence of endovanilloids.

8p dell39 03-04-2013 45 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Preventive effects of Flos Perariae (Gehua) water extract and its active ingredient puerarin in rodent alcoholism models...

8p coxanh_5 28-10-2011 58 4   Download