Activiti in action

This thesis documents a research program in which Australian grown Danshen extracts and related bioactive compounds have been demonstrated to be effective in scavenging free radicals, namely ROS generation, in a cell free system and NADPH oxidase derived superoxide (O2-) generation in vascular tissue (rat aorta). Danshen extracts, both aqueous and ethanol, and their active compounds (Tanshinone IIA, Salvianolic Acid B and Danshensu) demonstrated anti-oxidant activity however findings exhibited stronger activity in a cell free system than in the aortic vascular tissue.

138p runthenight07 01-03-2023 10 3   Download

The researcher of this project is a volunteer worker at the International Buddhist College of Victoria. Anecdotal evidence has put forwarded prior to this research that communication and relationships between parents and children in IBCV were deteriorating as a result of parents working long hours and children spending too much time playing computer games.

93p runthenight07 01-03-2023 11 3   Download

Master's thesis of Science "Investigation into the modulation of circadian clock proteins by dietary compounds and small molecules" is structured as follows: Chapter 1 Introduction; Chapter 2 Identification of novel bioactive compounds from Olea europaea by evaluation of chemical compounds in the OliveNetTM library: in silico bioactivity and molecular modelling, and in vitro validation of hERG activity; Chapter 3 Modulation of circadian core clock proteins by dietary compounds; Chapter 4 Molecular mechanisms of action of selected olive phenolics against epigenetic modifiers and the structur...

235p runthenight04 02-02-2023 5 3   Download

This action research project was conducted to aim at solving the problem of reticence in speaking activities which possibly caused students’ low achievement in English subject at university.

77p closefriend09 16-11-2021 31 3   Download

The aims of the study: Revealing factors that discourage students from taking part in speaking lessons and the factors that bring their low motivation in speaking class; examining language games applied during speaking classes to enhance the students participation and interest in speaking activities and measuring the effectiveness of language games by using action research.

77p closefriend09 16-11-2021 17 6   Download

The long-term goal of the research is to develop a series of appropriate pre-listening activities that help my college‟s students in listening comprehension. However, within the scope of this action research, the author first tried out a variety of prelistening activities for diversification and see how they work, which works well and which not. B

84p closefriend09 16-11-2021 31 5   Download

The objectives of the study are: To explore the activities which help students to improve vocabulary retention; to get to know the students‟ attitudes towards these activities. Mời các bạn cùng tham khảo nội dung chi tiết.

93p closefriend09 16-11-2021 20 4   Download

This action research, as stated in the preceeding section, was conducted with the aim of finding out the usefulness of role-play activities to the enhancement of the first-year undergraduates‟ fluency in speaking English in the context of the classroom at the Faculty of English Language of National Economic University.

74p closefriend09 16-11-2021 29 5   Download

This study aims to investigate the 8th grade students‟ problems towards learning reading, to understand how the diversification of reading activities helps improve the teaching and learning of reading and how students‟ attitudes towards learning reading change thanks to the application of the technique.

87p closefriend09 16-11-2021 22 3   Download

The aim of the study mainly focuses on the application of different types of pictures in teaching English-speaking skills to 4th graders in classroom speaking activities. Particularly, the primary purpose of the current study is to explore the benefits of using pictures in speaking lessons to the researcher‟s students. Besides, the study investigates these students‟ attitudes towards the use of pictures in classroom speaking activities.

87p closefriend09 16-11-2021 23 4   Download

The aim of the study was to solve the students’ problems in speaking lesson by using task-based activities. Then, the first objective was to verify the effectiveness of using task-based learning on the speaking performance of the 11th grade students at Diem Thuy high school. Specifically, it investigated whether TBL exerted any influence on students’ performance in speaking classes. The second objective was to explore students’ opinions towards the use of task-based learning in speaking lessons.

123p beloveinhouse04 01-09-2021 38 5   Download

Regulator of G-protein signaling (RGS) proteins were originally identified as negative regulators of G-protein-coupled receptor (GPCR) signaling via their GTPase-accelerating protein (GAP) activity. All RGS proteins contain evolutionarily conserved RGS domain; however, they differ in their size and regulatory domains. RGS1 and RGS10 are smaller than other RGS proteins, and their functions involve various inflammatory responses including autoimmune responses in both the periphery and the central nervous system (CNS). Neuroinflammation is the chronic inflammatory response in the CNS.

5p caothientrangnguyen 09-05-2020 28 2   Download

Look at the model of organization and operation of the banking system in the background of market economy and innovation trend toward state management activities of commercial banks. Research organization and operation of the State Bank as the subject of state management for commercial banks in Vietnam; studying the mechanism of action of the State Bank to the banking system performance in Vietnam.

26p change08 27-06-2016 55 5   Download

Overview emotion‘ perspectives Previous perspective Today’s perspectives and its importance Case study Intel Corp Position of emotion in today. Emotion and Emotional intelligence Dimensions of emotion How to focus on Positive and Active Don’t forget to let them catch their breath The emotional foundations of team effort Watch out for negative emotions The importance of recognizing emotional frameworks Using observational tools Attending to the nonverbal messages Solutions to overcome negative outlooks Stimulating positive feelings Creating an action orientation ...

17p sony_12 25-06-2013 72 8   Download

We have analyzed several mathematical models that describe inhibition of the factor VIIa–tissue factor complex (VIIa–TF) by tissue factor pathway inhibitor (TFPI). At the core of these models is a common mechanism of TFPI action suggesting that only the Xa–TFPI complex is the inhibitor of the extrinsic tenase activity. However, the model based on this hypothesis could not explain well all the available experimental data. Here, we show that a good quantitative description of all experimental data could be achieved in a model that contains two more assumptions....

16p research12 01-06-2013 37 6   Download

Duodenase is a 29-kDa serine endopeptidase that displays selective trypsin- and chymotrypsin-like substrate specificity. This enzyme has been localized to epitheliocytes of Brunner’s glands, and as described here, to mast cells within the intestinal mucosa and lungworm-infected lung, implying an important additional role in inflammation and tissue remodelling. In primary cultures of pulmonary artery fibroblasts, duodenase induced a concentration-dependent increase in [3H]thymidine incorporation with a maximal effect observed at 30 nM.

10p research12 01-06-2013 54 3   Download

We have previously demonstrated that the steroid hormone 1a,25(OH)2-vitamin D3 [1a,25(OH)2D3] stimulates the production ofinositol trisphosphate (InsP3), the breakdown product ofphosphatidylinositol 4,5-biphosphate (PtdInsP2) by phospholipase C (PtdIns-PLC), and activates the cyto-solic tyrosine kinase c-Src in skeletal muscle cells. In the present study we examined whether 1a,25(OH)2D3induces the phosphorylation and membrane translocation ofPLCc and the mechanism involved in this isozyme activation. ...

10p research12 29-04-2013 44 4   Download

The cAMP-dependent protein kinase (PKA) signaling pathway plays a major role in a number of pathophysio-logical conditions. However, there have been conflicting evidences regarding the action of cAMP/PKA on nuclear factor-jB(NF-jB). Inthis study,wehaveexplored the effect of cAMP/PKA on NF-jBactivity and determined its molecular mechanism. PKA activating agents or expression of thecatalyticsubunitofPKA(PKAc) inhibitedtheNF-jB-dependent reporter gene expression induced by tumor nec-rosis factora(TNFa). ...

7p research12 23-04-2013 33 4   Download

Microcin J25 (MccJ25) is the single macrocyclic antimicro-bial peptidebelonging to the ribosomally synthesizedclass of microcins that are secreted byEnterobacteriaceae.Itshowed potent antibacterial activity against severalSalmonellaand Escherichiastrains and exhibited a compact three-dimen-sional structure [Blondet al. (2001) Eur. J. Biochem., 268, 2124–2133]. The molecular mechanisms involved in the biosynthesis, folding andmode of action of MccJ25 are still unknown.

11p tumor12 22-04-2013 44 2   Download

The toxicity of the pea albumin 1b (PA1b), a 37 amino-acid peptide extracted from pea seeds, for cereal weevils (Sito-philus oryzae, Sitophilus granariusandSitophilus zeamais) was recently discovered.The mechanism of action of this new entomotoxin is still unknown and potentially involves a target protein in the insect tissues.This work describes the characterization of a high-affinity binding site for PA1b in a microsomal fraction ofSitophilusspp.extracts.Purified PA1b was labeled to a high specific radioactivity (c.

7p fptmusic 16-04-2013 37 3   Download