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Biological activity
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Highly concentrated extracts, known as extracted preparations, are collected by evaporating or drying solutions containing biologically active substances (BASs) found in herbs or animal parts through a leaching process with the assistance of appropriate solvents.
8p
viwalton
02-07-2024
1
0
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Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with complex signaling patterns including activation of several pathways such as MAPK, PI3K-AKT/mTOR and IL-6/JAK/STAT3 with the master regulator HIF-1, which in turn drive particular tumor behaviors determining, in the end, treatment outcomes and patients fate.
12p
vishanshan
27-06-2024
1
1
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Ten new chromone derivatives were synthesized from the original 2-4-6- trihydroxyacetophenone using microwave irradiation. The product's structures were confirmed by FT-IR, 1H-NMR, and 13C-NMR spectra data. The anti-microbial activities of the obtained compounds were tested by the disc diffusion method. The results showed that most chromones have significant biological activities against Candida albicans.
10p
viambani
18-06-2024
1
0
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In this paper, we present the synthesis of intermediate compounds 2 and 3, which are the key compounds for synthesizing the derivatives of schweinfurthin G using chiral ionic liquid. These compounds are the key blocks to further synthesize schweinfurthin G derivatives for biological activity tests.
8p
viamancio
04-06-2024
2
0
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The study on essential oils of various plantparts and their biological activities continues to be an important area of research and developmen. In the continuation of our current research on the identification of bioactive substances from plants of North East India.
21p
viamancio
04-06-2024
2
0
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Sarcosperma, which belongs to the Sapotaceae family, is composed of 11 species distributed in Asia, five of which are found in Viet Nam. As a result, in a recent paper, we reported on the isolation of two new compounds, sarcokontums A and B, from the stems and leaves of this plant.
10p
viamancio
04-06-2024
1
0
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In this study, a simple, straightforward, and highly efficient microwave-assisted three-component synthesis of novel 2-amino-4H-benzo[g]chromene-5,10-dione-3-carbonitrile derivatives bearing fluorine atoms has been developed using 1,4-diazabicyclo[2.2.2]octane (DABCO) as an ecofriendly catalyst, and acetonitrile as a solvent.
11p
viamancio
04-06-2024
1
0
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This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice.
175p
vimeyers
29-05-2024
3
2
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This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Peptides are important biological molecules and have various physiological actions. Peptide-based drug discovery may help bring about the development of useful medicines that are highly safe and show potent pharmacological effects in small doses.
113p
vimeyers
29-05-2024
3
2
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Ebook "Protein acetylation: Methods and protocols" expert researchers in the field detail many of the methods which are now commonly used to study protein acetylation. These include methods and techniques for identification of protein acetylation, column- and gel electrophoresis-based approaches, computationally prediction, and the biological response to protein acetylation.
279p
dongmelo
27-05-2024
2
2
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This study has demonstrated the presence of two compounds Genipin and Geniposide in Gardenia jasminoides Ellis.) collected in Thanh Luong commune, Thanh Chuong district, Nghe An province using the 1 H-NMR and 13C-NMR.
5p
vijaychest
16-05-2024
1
1
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The aim of this study was to evaluate the biological activity of some pyridine derivatives (compounds 1 to 15) on perfusion pressure in an isolated rat heart model. Furthermore, theoretical interaction of pyridine derivatives with the M2 muscarinic receptor was determined using acetylcholine, AF-DX 116 and the 3uon protein as theoretical tools in a docking model.
11p
dianmotminh02
03-05-2024
1
1
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The outcomes are to be compared with typical drugs given that compounds are examined against gram-positive and gram-negative strains of bacteria and fungus. Against bacterial strains, products with nitro, methyl, and bromo substituents in the p-position of the benzene ring, as well as products with the nitro group at the m-position, showed very excellent activities against bacterial strains, while compounds with chloro substituent at p-position and m-position demonstrated good activity against the fungal strains Aspergillus niger and Fusarium javanicum.
8p
dianmotminh02
03-05-2024
2
1
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In this study, we synthesized and compared their antimicrobial and hemolytic activity. Furthermore, the data was analyzed and interpreted based on the helical wheel model that represents the peptide secondary structure.
11p
dianmotminh02
03-05-2024
4
1
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Syzygium boisianum (Gagnep.) Merr. & L.M.Perry, locally named Tram bois, is widely distributed in primary or secondary forests of Vietnam, Thailand, and China. [6] For the first time, the current report provides information on chemical compositions in essential oil of S. boisianum leaves, collected from the northern part of central Vietnam. The obtained oil was also used to assess its antibacterial effects. The biological potential is highlighted by the molecular docking study.
6p
dianmotminh02
03-05-2024
4
1
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The biological activities of E. ciliata essential oils (Ec EOs) in Vietnam have yet to be thoroughly studied and have received less attention than other species of genus Elsholtzia in the world. In this study, we evaluated the antioxidant, antimicrobial, and anticancer of Ec EOs and examined their chemical compositions. Fresh leaves of E. ciliata were hydro-distilled to yield essential oil of 0.82% dry weight, respectively.
12p
dianmotminh02
03-05-2024
2
1
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In this study, we synthesized magnetic activated carbon (MAC) derived from Litsea glutinosa seeds, which was applied to eliminate methylene blue and nickel ions in the aeration tank of the biological treatment system. Structural characteristics and adsorption properties of MAC were studied. The obtained results revealed that the removal efficiency of these pollutants significantly improved as a combination of MAC and activated sludge, especially in the case of nickel ions removal.
7p
dianmotminh02
03-05-2024
2
1
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Cancer is the most destructive and fatal disease, representing an urgent medical challenge to the world. The discovery of a new anticancer candidate may help reduce or eliminate this alarming disease to a greater extent. On similar lines, in silico research was carried out on novel naphthylidene isoxazolidinedione derivatives that were logically conceived, synthesized, purified, and structurally characterized. In vitro biological evaluation revealed the most active compound 4d with an inhibitory concentration of 42.87 μM against K562 and 47.42 μM on A549 cells.
10p
dianmotminh02
03-05-2024
3
1
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In this study, an evaluation of the enantioselective of a chiral flavanone with 2'-OH substitution (5,7,2'- trihydroxyflavanone) on ring C was studied by high performance liquid chromatography using the cellulose tris(3,5- dimethylphenyl carbamate)-based stationary phase with n-hexane and iso-propanol doped with 0.1% (v/v) trifluoroacetic acid as a mobile phase.
6p
dianmotminh02
03-05-2024
1
1
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Alpinia vietnamica H.Ð. Tran, Luu & Skornick was identified as a new species in 2019, which is widely distributed in Thua Thien Hue, Quang Nam, and Kon Tum provinces, Vietnam. The current study wishes to report phytochemical investigation, and the biological activities (cytotoxic, antioxidative, and α-glucosidase inhibitory) of isolated compounds.
5p
dianmotminh02
03-05-2024
8
1
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