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Cell death
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Cervical cancer is the fourth most common cancer in women, with an estimated 342,000 deaths worldwide in 2020. Current standard of care in the UK for locally advanced cervical cancer is concurrent chemoradiotherapy with weekly cisplatin, yet 5-year overall survival rates are only 65% with a distant relapse rate of 50%.
10p
vishanshan
27-06-2024
1
1
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Ovarian cancer (OC) is a gynecological malignancy tumor with high recurrence and mortality rates. Programmed cell death (PCD) is an essential regulator in cancer metabolism, whose functions are still unknown in OC. Therefore, it is vital to determine the prognostic value and therapy response of PCD-related genes in OC.
17p
vishanshan
27-06-2024
1
1
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Clear cell renal cell carcinoma (ccRCC) is associated with a high prevalence of cancer-related deaths. This study aims to develop an efficient nomogram model for stratifying and predicting the survival of ccRCC patients based on tumor stage.
13p
vishanshan
27-06-2024
1
1
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PANoptosis is a specific type of inflammatory programmed cell death (PCD) modality that can be involved in three key modes of cellular programmed cell death-pyroptosis, apoptosis and necroptosis.
13p
vishanshan
27-06-2024
1
1
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Prostate cancer (PCa) is one of the major tumor diseases that threaten men’s health globally, and biochemical recurrence significantly impacts its prognosis. Disulfidptosis, a recently discovered cell death mechanism triggered by intracellular disulfide accumulation leading to membrane rupture, is a new area of research in the context of PCa. Currently, its impact on PCa remains largely unexplored.
12p
vishanshan
27-06-2024
3
1
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Glioblastoma is the most common and most aggressive malignant primary brain tumor in adults. Glioblastoma cells synthesize and secrete large quantities of the excitatory neurotransmitter glutamate, driving epilepsy, neuronal death, tumor growth and invasion.
7p
vishanshan
27-06-2024
2
1
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Epigenetic alterations contribute greatly to the development and progression of colorectal cancer, and effect of aberrant miR-622 expression is still controversial. This study aimed to discover miR-622 regulation in CRC proliferation.
12p
vishanshan
27-06-2024
1
1
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Pyroptosis is a type of programmed cell death mediated by the gasdermin family. Gasdermin B (GSDMB), as a member of gasdermin family, can promote the occurrence of cell pyroptosis. However, the correlations of the GSDMB expression in colorectal cancer with clinicopathological predictors, immune microenvironment, and prognosis are unclear.
13p
vishanshan
27-06-2024
1
1
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Combination therapy is the primary treatment for unresectable hepatocellular carcinoma (u-HCC). The hepatic functional reserve is also critical in the treatment of HCC. In this study, u-HCC was treated with combined hepatic arterial infusion chemotherapy (HAIC), tyrosine kinase inhibitors (TKIs), and programmed cell death protein-1 (PD-1) inhibitors to analyze the therapeutic response, progression-free survival (PFS), and safety.
10p
vishanshan
27-06-2024
2
1
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Cancer is a leading global cause of death. Conventional cancer treatments like surgery, radiation, and chemotherapy have associated side effects. Ferroptosis, a nonapoptotic and iron-dependent cell death, has been identified and differs from other cell death types.
9p
vishanshan
27-06-2024
1
1
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Pancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of cancer-related deaths globally. Its incidence is notably increasing. This poor prognosis is primarily due to late-stage diagnosis (approximately 70% to 80% of patients are diagnosed at an advanced stage), aggressive tumor biology, and low sensitivity to chemotherapy.
10p
vikoch
27-06-2024
3
1
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Many randomized controlled trials (RCTs) and network meta-analyses have demonstrated that the progression-free survival (PFS) and overall survival (OS) of advanced non-small cell lung cancer (NSCLC) patients can be improved through combination immunotherapy or monotherapies.
9p
vikoch
27-06-2024
1
1
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Prevention, diagnosis and treatment are the watchwords in stroke research, for basic neuroscientists and clinicians alike. This 2002 book, from the 22nd Princeton Conference on Cerebrovascular Disease, contains contributions from outstanding investigators on numerous topics in stroke research. The contents cover the status and future directions of stroke pathophysiology, diagnosis and treatment, with special emphasis on the molecular and cellular mechanisms of ischaemic cell death and repair, and clinical issues including imaging, risk factors and therapeutic strategies in stroke.
456p
vimeyers
29-05-2024
4
2
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Epidermal growthfactor receptor(EGFR) and human epithelium receptor-2(HER2) are members of the epidermal growth factor receptor (EGFR/ErbB) family implicated in the development of many types of carcinoma. Zanthoxylum simulans Hance has the effect of inhibiting growth and causing the death of many types of cancer cells. In this study, the molecular docking method and molecular dynamics simulations were used to evaluate the inhibition abilities of EGFR and HER2 receptors of 120 compounds in Zanthoxylum simulans Hance.
12p
dianmotminh02
03-05-2024
3
2
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Part 1 book "Fundamentals of pathology" includes content: Growth adaptations; cellular injury, and cell death inflammation; inflammatory disorders, and wound healing, principles of neoplasia; hemostasis and related disorders; red blood cell disorders; white blood cell disorders; vascular pathology; cardiac pathology; respiratory tract pathology tholog; gastrointestinal pathology.
120p
zizaybay1101
30-04-2024
3
2
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Part 1 book "Robbins basic pathology" includes content: The cell as a unit of health and disease; cell injury, cell death, and adaptations; inflammation and repair; hemodynamic disorders, thromboembolism, and shock; diseases of the immune system; neoplasia; genetic and pediatric diseases; environmental and nutritional diseases.
405p
zizaybay1101
30-04-2024
2
2
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Ebook "Protein folding and misfolding: Neurodegenerative diseases" is to review the molecular events initiated by unfolded or misfolded proteins leading to cell death via the development of pathological inclusions, with special emphasis on the macromolecular associations of the malfolded proteins into characteristic ultrastructures found in the cases of neurological disorders, some of them are shown in this issue.
284p
ladongphongthanh1008
22-04-2024
3
2
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Ebook "The proteasome in neurodegeneration" will be of relevance for many years to come, and are intended to generate interest in the nuances of the UPS system, and highlight new avenues for the understanding of the UPS and the generation of UPS-based therapies for the treatment of neurodegenerative diseases.
314p
ladongphongthanh1008
22-04-2024
4
2
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Ebook "Phase transitions in cell biology" should be suitable for anyone interested in the nature of biological function, particularly those who tire of lumbering along well trodden pathways of pursuit, and are eager to hear something fresh. The book is replete with fresh interpretations of familiar phenomena, and should serve as an excellent gateway to deeper understanding.
187p
ladongphongthanh1008
22-04-2024
3
2
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Ebook "Necrotic cell death" presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
402p
ladongphongthanh1008
22-04-2024
3
1
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