General population

Taxanes appear to be safe following the first trimester of pregnancy, with obstetric and fetal outcomes being similar to those observed in the general obstetric population. Future studies should aim to determine the most effective taxane regimen and dosage for use during gestation, with a specific focus on treatment safety.

8p vishanshan 27-06-2024 1 1   Download

Inadequate recognition of the care needs of this vulnerable population may hamper the harmonisation of evidence-based and person-centred care, compounded by issues such as stigma, misconceptions, and diagnostic overshadowing. This study therefore aimed to explore the needs of patients with ID from perspectives of both patients and of healthcare providers (HCPs) in the context of CDM in general practice.

13p vishanshan 27-06-2024 2 1   Download

The population is aging, leading to an increased need for palliative care and end-of-life care. There is a lack of research on the use of video consultations for knowledge transfer between specialist and general palliative care. The aim of this study was to describe healthcare professionals’ experiences of video consultations in palliative care in community homecare and nursing homes in rural areas.

7p vishanshan 27-06-2024 1 1   Download

We employed a system dynamics approach to assess and predict the effect of the general practitioner service package (GPSP) and complementary incentive policies on the contract rate for 2015–2030. First, the GPSP is designed to address the unique needs of occupational populations, enhancing the attractiveness of GP contracting services, including three personalized service contents tailored to demand-side considerations.

12p vishanshan 27-06-2024 1 1   Download

There are many different ways to do the philosophy of biology. At one end of a spectrum of possibilities would be works of general philosophical interest drawing on biological examples for illustration and support. This book aims to break new ground in the philosophy of biology. Before we turn to what is new, let us briefly look at the background from which contemporary philosophy of biology emerged.

603p vimeyers 29-05-2024 4 2   Download

This book is geared for all the investors and would-be investors out there who know the importance of managing their money for the future but who aren’t entirely certain how to go about it. That’s probably the majority of the general population. Public opinion polls tell us that more Americans think and worry about money—and how to invest it—than any generation in this country’s history. Part of this, as we’ll explain, is due to the fact that more of us are responsible for our own financial futures than ever before.

383p zizaybay1103 29-05-2024 5 2   Download

Ebook "Fundamentals of soil science (8th edition)" revision of a bestselling text shows that soil is three-dimensional and dynamic. This concept is developed in the first two chapters and is built on throughout the book. Chapters 3 through 7 explore soil physical properties and water, with expanded coverage of tillage and traffic and an increased emphasis on water and wind erosion processes. Chapters 8 through 11 discuss the biological aspects of soils as well as their mineralogical and chemical properties.

382p giangdongdinh 28-05-2024 3 1   Download

Pathogenic variants in BRCA1 and BRCA2 (BRCA1/2) lead to increased risk of breast, ovarian, and other cancers, but most variant-positive individuals in the general population are unaware of their risk, and little is known about prevalence in non-European populations. We investigated BRCA1/2 prevalence and impact in the electronic health record (EHR)-linked BioMe Biobank in New York City.

12p vibransone 28-03-2024 7 2   Download

The concentrations of the highly atherogenic lipoprotein(a) [Lp(a)] are mainly genetically determined by the LPA gene locus. However, up to 70% of the coding sequence is located in the complex so-called kringle IV type 2 (KIV-2) copy number variation, a region hardly accessible by common genotyping and sequencing technologies.

13p vibransone 28-03-2024 3 2   Download

The frequency of a variant in the general population is a key criterion used in the clinical interpretation of sequence variants. With certain exceptions, such as founder mutations, the rarity of a variant is a prerequisite for pathogenicity.

14p vioraclene 31-03-2024 7 2   Download

Ebook "Natural products in cancer prevention and therapy" addresses the hurdles and challenges in the practice of human cancer prevention in the general population. The process of slowing the progression of cancer is applicable to many cancers with long latency. Although cancer chemoprevention has proven to be a successful strategy in animals, its application to humans has met with limited success.

265p coduathanh1122 27-03-2024 3 1   Download

Copy-number variations (CNVs) have been associated with rare and debilitating genomic disorders (GDs) but their impact on health later in life in the general population remains poorly described. Methods Assessing four modes of CNV action, we performed genome-wide association scans (GWASs) between the copy-number of CNV-proxy probes and 60 curated ICD-10 based clinical diagnoses in 331,522 unrelated white British UK Biobank (UKBB) participants with replication in the Estonian Biobank.

24p vicwell 29-02-2024 3 2   Download

Ebook "Changing global perspectives on horseshoe crab biology, conservation and management" reports significant progress of scientific research on horseshoe crabs, including aspects of evolution, genetics, ecology, population dynamics, general biology and physiology, within the recent 10 years. It also highlights the emerging issues related to world-wide conservation threats, status and needs. The contributions in this book represent part of an ongoing global effort to increase data and concept sharing to support basic research and advance conservation for horseshoe crabs.

619p duongthandue0501 28-02-2024 2 1   Download

Ebook "Modelling our changing World" focuses on the concepts, tools and techniques needed to successfully model ever-changing time-series data. It emphasizes the need for general models to account for the complexities of the modern world and how these can be applied to a range of issues facing Earth, from modelling volcanic eruptions, carbon dioxide emissions and global temperatures, to modelling unemployment rates, wage inflation and population growth.

142p manmanthanhla0201 27-02-2024 1 1   Download

Human immunodeficiency virus-infected patients are 100 times more likely to develop aseptic osteonecrosis compared with the general population. While 90% of cases concern the femoral head, the involvement of humeral bone remains rare.

3p vilazada 31-01-2024 5 2   Download

Allergic rhinitis is the most common allergic disease, with a prevalence up to 40% in the general population. Allergic rhinitis requires daily treatment to block inflammatory mediators and suppress the inflammatory response.

9p vitiki 30-01-2024 2 2   Download

Nitrous oxide is a medical and household gas that has seen its use drift to recreational purpose among the young population in recent years. Significant neurological, hematological and psychiatric side effects, generally related to an induced functional vitamin B12 deficiency, have been described separately in the literature.

7p vitiki 30-01-2024 5 2   Download

Part 1 book "Agricultural medicine - Rural occupational and environmental health, safety, and prevention" includes content: Introduction and overview; special risk populations in agricultural communities; agricultural respiratory diseases; agricultural skin diseases; cancer in agricultural populations; health effects of agricultural pesticides; general environmental hazards in agriculture communities.

322p muasambanhan05 22-01-2024 3 2   Download

Part 1 book "Field manual for small animal medicine" includes content: Introduction to working in the field, stray dog population management, community engagement and education, humane canine handling, capture, and transportation, operating a field spay neuter clinic, general anesthesia and analgesia, regional anesthesia and local blocks, nonsurgical fertility control, spay neuter surgical techniques, ancillary surgical procedures.

276p muasambanhan04 07-01-2024 3 1   Download

Part 1 book "Ecology of invertebrate diseases" includes content: General concepts in the ecology of invertebrate diseases, methods for studying the ecology of invertebrate diseases and pathogens, the pathogen population, the host population, abiotic factors, the biotic environment, viruses, bacteria

350p muasambanhan03 02-01-2024 6 2   Download