Genetic analysis

Mucopolysaccharide IVA is a rare recessive genetic disease resulting from a deficiency of N 6 sulfatase acetylgalactosamine (galactose 6 sulfatase) - a lysosome’s enzyme necessary to degrade keratan sulfate and chondroitin sulfate. Objectives: To describe clinical characteristics and genetic analysis of 13 children with MPS IVA in National Pediatric Hospital.

8p viengfa 28-10-2024 2 2   Download

The results of using machine learning via genetic programming (GP) to automatically generate novel effective length factor formula in accordance with AISC standard are presented in this article. The data points obtained from applying the numerical method equation solving for the transcendental equation for the effective length of the braced frame were fed into the machine learning algorithm.

5p vibecca 01-10-2024 3 1   Download

This study was therefore designed to evaluate the physical and physiochemical quality characteristics of inbred varieties with diverse origins and released in different periods in North Vietnam to determine the level of genetic divergence through cluster analysis.

10p vibecca 01-10-2024 1 1   Download

The objectives of this study were to identify promising rice genotypes and evaluate the genetic variance and effectiveness of selection of the rice varieties for several yield attributing traits. A varietal trial of fifteen rice genotypes was laid out in a randomized complete block design (RCBD) with three replications in a farmer’s field in Sundarbazar, Lamjung, Nepal during the rainy season of 2018.

13p vibecca 01-10-2024 3 2   Download

Microsatellite (MS) is a genetic marker widely used in the studies of pedigree, individual identification, gene mapping, and genetic diversity within and between populations. The genetic diversity of the indigenous Ven dog breed, along with two imported dog breeds, the Berger and Poodle dogs raised in Vietnam, was analyzed based on seven microsatellite markers.

8p viling 27-09-2024 6 2   Download

This study presents the results of correlation analysis between morphological characteristics and the rbcL marker in the identification of Padina seaweed samples collected at Hon Thom, Phu Quoc, Kien Giang province (HTO), Vietnam. The phylogenetic tree and genetic distance between HTO with references showed the samples belonging to Padina australis.

12p viling 27-09-2024 4 2   Download

The hereditary spastic paraplegias (HSPs) are a group of disorders characterised by progressive lower limb weakness and spasticity. This case highlights the challenge of distinguishing HSP from other chronic spinal cord diseases and emphasizes the role of genetic analysis in rare cases of spastic paraplegia.

4p viling 27-09-2024 2 2   Download

This study presents the development of a software support system aimed at improving targeted treatment outcomes in non-small cell lung cancer (NSCLC) by utilizing genetic mutation analysis data. PubMed BERT model were generated to identify tumor gene mutated features associated with gene-drug responses.

14p vinatisu 23-08-2024 5 2   Download

Cathelicidins include antimicrobial peptides (AMPs) and are involved in the innate immune defense against infections in mammals. Polymorphisms in the DNA sequence of cathelicidin genes could be relevant to inherited variations of host innate immunity, adaptation, and pathogen resistance. This study aims to investigate the sequence polymorphism of cathelicidin genes including CATHL2 and CATHL4 from local indigenous yellow cattle breeds of Vietnam.

11p dianmotminh02 03-05-2024 12 2   Download

The research project deals with two different types of data for two separate analysis. The first analysis deals with normalised RNA-seq breast cancer data where machine learning techniques are used to classify and identify the biomarker of cancer. Second analysis deals with raw DNA methylated leukemia samples to determine the mutations.

102p runthenight04 02-02-2023 7 4   Download

Osteosarcoma (OS) is a differentiation disease caused by the genetic and epigenetic differentiation of mesenchymal stem cells into osteoblasts. OS is a common, highly malignant tumor in children and adolescents. Fifteen to 20 % of the patients find distant metastases at their first visit.

13p vielonmusk 21-01-2022 21 0   Download

Wilms tumor is a highly heritable malignancy. Aberrant METTL14, a critical component of N6-meth‑ yladenosine (m6 A) methyltransferase, is involved in carcinogenesis. The association between genetic variants in the METTL14 gene and Wilms tumor susceptibility remains to be fully elucidated.

10p vielonmusk 21-01-2022 20 0   Download

Cancer-related fatigue (CRF) is one of the most common and distressing complaints reported by cancer patients during chemotherapy considerably impacting all aspects of a patient’s life (physical, psychosocial, professional, and socioeconomic).

11p vielonmusk 21-01-2022 14 1   Download

Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with only traditional risk factors is still not clear. Hence, our primary aim was to summarize literature on risk prediction models including genetic variants for CRC, while our secondary aim was to evaluate the improvement of discriminatory accuracy when adding SNPs to a prediction model with only traditional risk factors.

21p vielonmusk 21-01-2022 15 1   Download

Research purpose: Determine the composition, structure of mitochondrial genome, compare the difference in sequence, identify specific genetic characteristics of the six indigenous pig breeds, thereby contributing to the database to identification and conservation.

27p extraenglish 24-05-2021 22 4   Download

Research objective: Establish the genetic variants database of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Identification of genotype and allele frequencies of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Perform in silico functional analysis of novel variants.

27p extraenglish 24-05-2021 27 4   Download

The generation mean analysis involving six generations (P1, P2, F1, F2, B1 and B2) was carried out to study the nature and magnitude of gene effects for seventeen characters in okra. The study was conducted at Departmental Farm of Department of Agricultural Botany, College of Agriculture, VNMKV Parbhani during Kharif-17 season.

11p trinhthamhodang11 27-04-2021 18 2   Download

Hence this present study was planned to assess the genetic variability, correlation and path analysis for various yield and fibre quality characters in a set of genotypes.

10p chauchaungayxua10 19-03-2021 17 3   Download

Establish the genetic variants database of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Identification of genotype and allele frequencies of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Perform in silico functional analysis of novel variants.

27p capheviahe27 23-02-2021 5 3   Download

Collecting complete data of mitochondrial genome of 6 indigenous pig breeds in Vietnam (I, Mong Cai, Muong Lay, Huong, Muong Khuong and Ha Lang pigs) and deposited on the Genebank; determine the composition, structure of mitochondrial genome, compare the difference in sequence, identify specific genetic characteristics of the six indigenous pig breeds, thereby contributing to the database to identification and conservation.

27p capheviahe26 25-01-2021 14 4   Download