Natural compounds

Astaxanthin (AST) and pycnogenol (PYC) are natural bioactive compounds commonly used in pharmaceuticals and functional foods due to their highly antioxidant activity and potential health benefits. However, the widespread application of astaxanthin is hindered by its poor water solubility and highly unsaturated structure. In this study, nanoparticles co-delivering astaxanthin and pycnogenol (NAP) were fabricated to enhance the dispersibility, stability, and bioavailability of astaxanthin.

9p vifilm 11-10-2024 1 0   Download

In Vietnam, a tea-producing country, the tea buds and top three leaves are normally used for tea production while older leaves are pruned and discarded as agricultural waste in the winter. The present study aimed to exploit catechins from pruned tea leaves and use them as natural antioxidants for applications in the food industry.

12p vibecca 01-10-2024 4 2   Download

Endophytic microbes of medicinal plants are known to involve the synthesis of several bioactive compounds, which promote plant growth and resistance to diseases. In order to investigate endophytes in the important medicinal plant Catharanthus roseus, 16 endophytic microorganism strains were isolated from root samples of C. roseus var. roseus and C. roseus var. ocellatus naturally growing in coastal areas of Nha Trang, Vietnam.

12p viling 27-09-2024 4 2   Download

Avocado peel has been considered as a potential source of natural antioxidants in which phenolics are among the most important compounds. Therefore, this study aims to optimize the extraction process of phenolics using response surface methodology and evaluate the corresponding antioxidant activity.

11p vifaye 20-09-2024 2 1   Download

Resveratrol is a naturally occurring compound with anti-inflammatory properties. However, the protective molecular mechanisms of resveratrol against LPS-induced inflammation have not been thoroughly known. In the present study, we examined the antiinflammatory effect of resveratrol in inflammatory model using murine macrophage-like cell RAW264.7 stimulated with LPS. Resveratrol suppressed the production of inflammatory cytokines in LPS-stimulated RAW264.7 cells with the IC50 value as 17.5 ± 0.7 μM for IL-6, 14.2 ± 1.9 μM for IL-10, and 18.9 ± 0.6 μM for TNF-α.

9p xuanphongdacy06 18-09-2024 1 1   Download

The use of natural-origin active compounds in disease treatment is currently a prevailing trend. Mangiferin, a major component found in mangoes, is present in relatively high proportions. To develop a formulation and process for producing nano mangiferin using the selfassembly method with phosphatidylcholine and chitosan.

10p vinatisu 29-08-2024 5 0   Download

In order to explore the importance of the Antheroporum genus in pharmaceutical applications, two bioactivities of A. harmandii plant extracts have been evaluated in this study. Antimicrobial and antioxidant activities of A. harmandii extracts will provide evidences for further chemical composition studies to detect new bioactive compounds from this species.

9p dianmotminh02 03-05-2024 6 2   Download

In this study, we used the reliable GC-FID/MS technique to analyze the methyl ester derivatives of 37 different kinds of fatty acids. The results showed that high saturated fat concentration in all samples was mostly palmitic acid, whereas the low unsaturated fatty acid content in the cis form was primarily oleic acid and linoleic acid. The amount of monounsaturated and polyunsaturated fats is quite low.

6p dianmotminh02 03-05-2024 2 2   Download

The Department of Organic Chemistry, the Department of Inorganic and Applied Chemistry, and the Department of Chemistry are among the six departments, six majors, and three research laboratories that make up the Faculty of Chemistry today, some 70 years after its founding. Physical chemistry, analytical chemistry, polymer chemistry, medicinal chemistry, and three key-research labs, including the labs for natural compounds, cancer, and computational chemistry.

6p dianmotminh02 03-05-2024 7 1   Download

Flavonoids are a diverse group of natural compounds extensively studied in various research articles. They are widely distributed in the plant kingdom and exhibit various biological activities, including antioxidant, antiinflammatory, anticancer, antiviral, and antimicrobial effects. The genus Knema Lour., which contains many species in Southeast Asia, has been traditionally used to treat various ailments. The current review aims to provide a comprehensive update on the isolation of flavonoids and other secondary metabolites from the genus Knema Lour. between 1978 and 2022.

15p dianmotminh02 03-05-2024 10 4   Download

This history of antimicrobials is marked with impressive discoveries, the majority of which have their origin in natural products. However in this work, the antimicrobial activity of β- nitrostyrenes and related compounds of synthetic origin is reviewed and investigated with a particular focus on the influence of fluorine functionality. Various fluorinated β-methyl-β-nitrostyrene compounds were prepared, their minimum inhibition concentration in cultures of Gram positive, Gram negative and a fungus and their lipophilicity was determined.

133p runthenight05 01-03-2023 5 3   Download

The focus of this thesis was to study the chemotaxonomic relationship of selected southern Australian marine brown algae of the genera Cystophora and Sargassum. Consequently, this resulted in the isolation and structure elucidation of six new terpenoids from two southern Australian marine brown algae Cystophora moniliformis and Sargassum fallax together with 10 previously reported natural products. As a result of the re-isolation of these known secondary metabolites, updated and complete structural characterisation data could be provided for the first time for 7 of these compounds.

132p runthenight07 01-03-2023 7 3   Download

The objectives of the thesis: Study on chemical composition of Paramignya trimera and Morinda longissima species. Evaluation of hepatoprotective and anti-HBV activities of extracts and pure compounds from stems and roots of Xao tam phan (Paramignya trimera (Oliv.) Guill.) and Nho dong (Morinda longissima Y.Z. Ruan).

22p extraenglish 24-05-2021 28 3   Download

The aim of the thesis: Study on chemical composition of starfish Acanthaster planci of Vietnam, synthesizing hydroxyl and oxime derivatives from a steroid isolated from this starfish and assessing biological activity of isolated and synthesized compounds.

26p extraenglish 24-05-2021 20 4   Download

The research objectives of the thesis: Isolate and determine the chemical structure of compounds from C. candicans and C. macrophylla species collected in Vietnam. Assessment of toxic activity on some cancer cell lines: liver (Hep-G2), lung (Lu-1) and breast (MCF-7) of isolated clean compounds. Researching the chemical composition of C. candicans and C. macrophylla essential oils

29p extraenglish 24-05-2021 16 4   Download

With the aim of searching for bioactive compounds from plants of the genus Garcinia in order to contribute to the scientific basis for further research in the pharmaceutical field, the thesis focuses on studying two species of the genus Garcinia is Garcinia cowa and Garcinia hanburyi.

27p capheviahe27 23-02-2021 12 4   Download

The objectives of the thesis: Study on chemical constituents of two species Markhamia stipulata var. canaense V.S. Dang and Stereospermum binhchaunesis V.S. Dang; evaluation of biological activities of isolated compounds to find potential compounds.

27p capheviahe27 23-02-2021 14 3   Download

Research purposes of the dissertation: Studying on Dalbergia tonkinensis Prain systematicly and fully about: plants (microsurgery, gene sequences), chemical compositions and biological activity.

27p capheviahe27 23-02-2021 12 2   Download

The molecular properties of apigenin, luteolin and nevadensin which are three naturally flavonoid compounds have been studied theoretically by DFT method at 6- 311++G(d,p) level. All FMO analysis, mechanism, and kinetics studied suggested that compound luteolin (3) was a promising antioxidant agent. The results indicated that HAT is thermodynamically preferred in the gas phase, and SPLET is the thermodynamically favorable pathway in methanol and water.

11p nguaconbaynhay10 19-02-2021 18 3   Download

Study on chemical composition of starfish Acanthaster planci of Vietnam, synthesizing hydroxyl and oxime derivatives from a steroid isolated from this starfish and assessing biological activity of isolated and synthesized compounds.

26p capheviahe26 25-01-2021 10 4   Download