Reactions taking place

DFT calculations indicate that the decomposition reaction of nitroethyl benzoates in the presence of 1,3-dimethylimidazolium cation takes place much faster than in the case of the non-catalyzed process. Additionally, our calculations suggest one-step polar mechanism of title reactions.

8p tocectocec 25-05-2020 13 1   Download

GTP is an allosteric activator of CTP synthase and acts to increase thekcat for the glutamine-dependent CTP synthesis reaction. GTP is suggested, in part, to optimally orient the oxy-anion hole for hydrolysis of glutamine that takes place in the glutamine amidotransferase class I (GATase) domain of CTP synthase.

9p awards 05-04-2013 42 3   Download

Signal transduction pathways are often embedded in com-plex networks, which result from interactions between pathways and feedback circuitry. In order to understand such networks, qualitative information on which inter-actions take place and quantitative data on their strength become essential.

9p awards 05-04-2013 46 5   Download

Receptors should be properly analysed in view of the microenvironment in which they are embedded. Therefore, the concept of ‘receptosome’ was for-mulated to the complex interactions taking place between receptors and other proteins at the plasma membrane level, and to explain very heteroge-neous or divergent cellular responses to common epigenetic factors and modifications to the extracellular environment.

12p vinaphone15 27-02-2013 42 2   Download

DYRK1A is a dual-specificity protein kinase that autophosphorylates a conserved tyrosine residue in the activation loop but phosphorylates exoge-nous substrates only at serine or threonine residues. Tyrosine autophospho-rylation of DYRKs is a one-off event that takes place during translation and induces the activation of the kinase.

14p viettel02 20-02-2013 34 4   Download

Most of the biochemical and biophysical processes of proteins take place at membranes, and are thus under the influence of strong local electric fields, which are likely to affect the structure as well as the reaction mecha-nism and dynamics.

9p cosis54 05-01-2013 47 4   Download

Aldehydes and Ketones – Form acetals and ketals respectively with normal methanol-containing reagents – Water formed in this reaction will then be titrated to give erroneously high water results – With aldehydes a second side reaction can take place, consuming water, which can lead to sample water content being underestimated – Replacing methanol with another solvent can solve the difficulties (commercial reagents are widely available)

14p qdung92ct 03-07-2012 73 6   Download