RNA gene
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Part 2 book "Modern biotechnology - Connecting innovations in microbiology and biochemistry to engineering fundamentals" includes content: Enzymes, enzyme kinetics, metabolism, biological energetics, metabolic pathways, genetic engineering - DNA, RNA, and genes; metabolic engineering; genomes and genomics.
269p dianmotminh04 12-07-2024 0 0 Download
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Part 1 book "Plant epigenetics and epigenomics - Methods and protocols" includes content: Landscaping plant epigenetics, the gene balance hypothesis - dosage effects in plants; inference of allele specific expression from RNA seq data 5 screening for imprinted genes using high resolution melting analysis of PCR amplicons; analysis of genomic imprinting by quantitative allele specific expression by pyrosequencing,... and other contents.
20p dianmotminh04 12-07-2024 0 0 Download
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Bài giảng Khoa học tự nhiên lớp 9 - Bài 39: Quá trình tái bản, phiên mã và dịch mã (II, III) trình bày về khái niệm của quá trình phiên mã (tổng hợp RNA); phiên mã ở sinh vật; sinh vật nhân thực; quá trình tổng hợp phân tử RNA từ gene;...Mời các bạn cùng tham khảo!
24p lannhungdungduyen 09-07-2024 2 2 Download
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Bài giảng Khoa học tự nhiên lớp 9 - Bài 37: Nucleic acid và ứng dụng (CTST) được biên soạn với mục tiêu giúp các em học sinh nêu được khái niệm nucleic acid.
60p lannhungdungduyen 08-07-2024 6 1 Download
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The primary aim of this study is to critically evaluate and comment on the research presented in the article titled “A Novel Super-Enhancer-Related Gene Signature Predicts Prognosis and Immune Microenvironment for Breast Cancer” by Wu et al.
3p vishanshan 27-06-2024 1 1 Download
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Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer mortality. Nevertheless, little is known about the underlying molecular mechanisms. This research aimed to investigate differentially expressed genes (DEGs) and explore their function in Lewis lung carcinoma (LLC)-bearing mice exposed to chronic intermittent hypoxia (CIH) by transcriptome sequencing.
10p vishanshan 27-06-2024 1 1 Download
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Ovarian cancer (OC) is a complex disease with significant tumor heterogeneity with the worst prognosis and highest mortality among all gynecological cancers. Glycosylation is a specific post-translational modification that plays an important role in tumor progression, immune escape and metastatic spread. The aim of this work was to identify the major glycosylation-related genes (GRGs) in OC and construct an effective GRGs signature to predict prognosis and immunotherapy.
16p vikoch 27-06-2024 1 1 Download
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This study aimed to identify metabolic subtypes in ESCA, explore their relationship with immune land‑ scapes, and establish a metabolic index for accurate prognosis assessment. Methods Clinical, SNP, and RNA-seq data were collected from 80 ESCA patients from the TCGA database and RNAseq data from the GSE19417 dataset. Metabolic genes associated with overall survival (OS) and progression-free survival (PFS) were selected, and k-means clustering was performed.
16p vikoch 27-06-2024 1 1 Download
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In this study, we established the relationship between male infertility and single nucleotide polymorphisms (SNPs) of TDRD1 (rs541192490, rs77559927) among 310 Vietnamese men (160 infertile patients and 150 healthy controls). Genotypes of single nucleotide polymorphisms of the TDRD1 gene (SNPs) were identified using the PCR-RFLP method.
9p dianmotminh02 03-05-2024 1 1 Download
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This study reported that the CHI4A gene was isolated from P. mirifica to validate the CHI4A unigenes obtained from the P. mirifica transcriptomic database (data not shown). This work provides more information about the variation and protein profile of the CHI4A gene for further experiments.
8p dianmotminh02 03-05-2024 7 2 Download
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Ebook "Systems biology of RNA binding proteins" provides case studies of RNA binding proteins that regulate aspects of RNA processing that are important for fundamental understanding of diseases and development. Chapters include systems-level perspectives, mechanistic insights into RNA processing and RNA Binding proteins in genetic variation, development and disease. The content focuses on systems biology and genomics of RNA Binding proteins and their relation to human diseases.
474p ladongphongthanh1008 22-04-2024 6 1 Download
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Ebook "Frontiers in computational and systems biology" consists of 19 chapters and covers a wide spectrum of topics. Described applications of an RNA structure sampling algorithm to the rational design of short interfering RNAs for gene silencing by RNA interference and to target identification for microRNAs that play important roles in posttranscriptional gene regulation.
411p ladongphongthanh1008 22-04-2024 5 2 Download
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In ebook "Cell-based microarrays: Review of applications, developments and technological advances" cell-based microarrays have advanced significantly to include expression arrays, short interfering RNA arrays and antibody arrays. The surface used to coat the glass slides has also been significantly improved to allow non-adherent cells to bind to the arrays.
108p tracanhphuonghoa1007 22-04-2024 4 1 Download
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Exosomes are promising tools for improving cancer care, but conversely may also contribute to tumor progression. Here, we highlight recently discovered roles of exosomes in modulating immune responses in cancer, with emphasis on exosomal surface proteins and on RNA and DNA content. We also discuss how exosomes could be exploited as biomarkers and delivery vehicles in cancer therapy.
4p vibransone 28-03-2024 2 2 Download
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CRISPR/Cas9 has revolutionized cancer mouse models. Although loss-of-function genetics by CRISPR/Cas9 is wellestablished, generating gain-of-function alleles in somatic cancer models is still challenging because of the low efficiency of gene knock-in.
11p vibransone 28-03-2024 4 2 Download
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Intrachromosomal triplications (TRP) can contribute to disease etiology via gene dosage effects, gene disruption, position effects, or fusion gene formation. Recently, post-zygotic de novo triplications adjacent to copynumber neutral genomic intervals with runs of homozygosity (ROH) have been shown to result in uniparental isodisomy (UPD).
14p vibransone 28-03-2024 6 2 Download
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Somatic genetic testing is rapidly becoming the standard of care in many adult and pediatric cancers. Previously, the standard approach was single-gene or focused multigene testing, but many centers have moved towards broad-based next-generation sequencing (NGS) panels.
14p vibransone 28-03-2024 4 2 Download
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Genome-wide association studies have identified over 160 loci that are associated with coronary artery disease. As with other complex human diseases, risk in coronary disease loci is determined primarily by altered expression of the causal gene, due to variation in binding of transcription factors and chromatin-modifying proteins that directly regulate the transcriptional apparatus.
18p vibransone 28-03-2024 4 1 Download
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Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease, and gene expression profiling has identified several molecular subtypes with distinct biological and clinicopathological characteristics. While MIBC subtyping has primarily been based on messenger RNA (mRNA), long non-coding RNAs (lncRNAs) may provide additional resolution.
13p vibransone 28-03-2024 4 2 Download
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Angiosarcoma is an aggressive tumor. Recent case series describe exceptional responses to checkpoint blockade in this disease. Methods: Herein, we explored the genomic correlates of 48 angiosarcomas from the Angiosarcoma Project (12,499 variants analyzed in 6603 genes; whole-exome sequencing) versus 10,106 pan-cancer tumors in The Cancer Genome Atlas including 235 sarcomas but no angiosarcoma.
6p vibransone 28-03-2024 4 2 Download