Serum albumin

Malnutrition is a disintegrating component to outcome of treatment childhood cancer. This research was carried out to assess nutritional status of children newly diagnosed with cancer under syearsold.

6p vinatisu 29-08-2024 3 2   Download

Studies on nanoparticle-protein interaction have also not been studied. This would give information on ratio influence on the structural alteration of EGCg in EGCg-AuNPs and its functionality in vivo. Herein, the optimisation of EGCg-AuNPs will be determined with a large pool of stoichiometric synthesises of gold and EGCg. These optimised EGCg-AuNPs would then be studied with bovine serum albumin (BSA) for protein interactions, binding and thermodynamics.

177p runthenight07 01-03-2023 6 3   Download

This study aims to evaluate the role of the fibrinogen/albumin ratio (FAR) in predicting platinum resistance and survival outcomes of patients with ovarian clear cell carcinoma (OCCC). Methods: Coagulation function and D-dimer, serum albumin, CA125 and HE4 levels were measured before surgery in OCCC patients undergoing initial surgery in our institution.

10p vielonmusk 21-01-2022 16 1   Download

Mục tiêu của đề tài là tinh sạch được enzyme xylanase từ chủng Aspergillus niger tái tổ hợp; đánh giá các tính chất lý hóa của xylanase tái tổ hợp; thử nghiệm khả năng thủy phân của enzyme xylanase tái tổ hợp và enzyme xylanase tự nhiên.

70p beloveinhouse03 22-08-2021 20 6   Download

Trong nghiên cứu này, cao chiết từ sinh khối nấm và quả thể nấm C. takaomontana DL0038A được nuôi cấy lỏng – tĩnh và khảo sát hoạt tính kháng oxy hóa in vitro bằng phương pháp thử năng lực khử, bắt gốc tự do DPPH (1,1- diphenyl-2-picrylhydrazyl) và ABTS (2,2´azinobis(3-ethylbenzothiazonline-6-sulfonate); và hoạt tính kháng viêm bằng phương pháp ức chế xanthine oxidase (XO) và ức chế biến tính bovine serum albumin (BSA).

11p vichaeng2711 29-04-2021 70 2   Download

Bài viết đưa ra mô hình tính toán dựa trên cơ sở lý thuyết Mie và hiện tượng luận GinzburgLandau để mô tả sự ảnh hưởng biến tính nhiệt dị thường của protein bovine serum albumin (BSA) lên hệ phức hạt cầu nano vàng-protein.

7p vimississippi2711 08-12-2020 38 1   Download

To investigate of nutritional status in maintenance hemodialysis patients by indicators: anthropometric, dietary energy, and protein intake, dialysis malnutrition score, serum albumin, prealbumin levels. To Understand the relationship between nutritional status and some clinical and laboratory characteristics, initially assessing the results of an oral nutritional supplement on nutritional status in 12 weeks in maintenance hemodialysis patients.

24p angicungduoc6 21-07-2020 22 2   Download

To investigate of malnutrition by using indicators: SGA_3, Body Mass Index, serum prealbumin, serum albumin, normalized protein catabolic rate (nPCR) and serum leptin concentration in patients with chronic kidney disease are on Hemodialysis and continuous peritoneal dialysis at Can Tho General Hospital. To find the factor related malnutrition, serum leptin levels and clinical, subclinical, and all-cause mortality in 12 months in these two patient groups.

27p cothumenhmong6 17-07-2020 28 1   Download

Nhằm phục vụ phát triển bộ KIT ELISA phát hiện nhanh độc tố vi tảo domoic acid trong sản phẩm hải sản tại Việt Nam, kháng thể kháng độc tố này đã được thử nghiệm thu nhận bằng liệu pháp miễn dịch đối với thỏ trắng New Zealand, thông qua sử dụng 250 µg và 500 µg phức hợp kháng nguyên domoic acid - dissuccinyl substrate - bovine serum albumin.

7p viathena2711 10-10-2019 33 1   Download

Lựa chọn phương pháp thích hợp để tạo cộng hợp, xác định mật độ gắn OTA lên albumin huyết thanh bò (Bovine Serum Albumin, BSA) và đánh giá đáp ứng kháng thể tạo thành của cộng hợp OTA-BSA tự tạo so với OTA-BSA thương mại.

8p vinasa2711 11-09-2019 29 1   Download

Các hạt nano ormosil được tổng hợp bằng phương pháp Stöber từ precursor Methyltriethoxysilane CH3Si(OC2H5)3 (MTEOS). Hạt nano ormosil pha tâm mầu Rhodamine B (RB) dạng cầu, phân tán trong nước, kích thước vài chục nano mét, có các nhóm chức năng như -NH2, -SH, -OH trên bề mặt. Hạt được bọc bằng bovine serum albumin (BSA). Các hạt nano huỳnh quang được gắn kết với các kháng thể đặc hiệu vi khuẩn Escherichia coli O157:H7. Vi khuẩn E.Coli O157:H7 được đánh dấu huỳnh quang bằng hạt nano ormosil thông qua tương tác và nhận biết đặc hiệu kháng nguyên - kháng thể.

9p cumeo2425 02-07-2018 77 2   Download

Department of Chemistry ‘IFM’, University of Torino, Italy; 2Department of Biology, University ‘Roma Tre’, Rome, Italy; 3Department of Structural and Functional Biology, University of Insubria, Italy Haem binding to human serum albumin (HSA) endows the protein with peculiar spectroscopic properties. Here, the effect of ibuprofen and warfarin on the spectroscopic properties of ferric haem –human serum albumin (ferric HSA–haem) and of ferrous nitrosylated haem –human serum albumin (ferrous HSA –haem-NO) is reported.

7p system191 01-06-2013 46 3   Download

A comparative study of thermodynamic and kinetic aspects of Cu(II) and Ni(II) binding at the N-terminal binding site of human and bovine serum albumins (HSA and BSA, respectively) and short peptide analogues was performed using potentiometry and spectroscopic techniques. It was found that while qualitative aspects of interaction (spectra and structures of complexes, order of reactions) could be reproduced, the quantitative parameters (stability and rate constants) could not.

9p research12 01-06-2013 38 4   Download

Human serum albumin (HSA) is best known for its extraordinary ligand binding capacity. HSA has a high affinity for heme and is responsible for the transport of medium and long chain fatty acids. Here, we report myri-state binding to the N and B conformational states of Mn(III)heme–HSA (i.e. at pH 7.0 and 10.0, respectively) as investigated by optical absorbance and NMR spectroscopy. At pH 7.0, Mn(III)heme binds to HSA with lower affinity than Fe(III)heme, and displays a water molecule coordinated to the metal....

12p fptmusic 12-04-2013 44 4   Download

The reactions of a few representative gold(III) complexes – [Au(ethylenediamine)2 ]Cl3 , [Au(diethylentriamine)Cl]Cl2 , [Au(1,4,8,11-tetraazacyclotetradecane)](ClO4 )2Cl, [Au(2,2¢, 2¢-terpyridine)Cl]Cl2,[Au(2,2¢-bipyridine)(OH)2][PF6]and the organometallic compound [Au(6-(1,1-dimethylbenzyl)-2,2¢-bipyridine-H)(OH)][PF6] – with BSA were investigated by the joint use of various spectroscopic methods and separation techniques.

7p fptmusic 12-04-2013 36 2   Download

Cys34 in domain I of the three-domain serum protein albumin is the bind-ing site for a wide variety of biologically and clinically important small molecules, provides antioxidant activity, and constitutes the largest portion of free thiol in blood. Analysis of X-ray structures of albumin reveals that the loop containing Tyr84 occurs in multiple conformations. In structures where the loop is well defined, there appears to be an H-bond between the OH of Tyr84 and the sulfur of Cys34.

10p awards 05-04-2013 36 3   Download

The changes in the far-UV CD signal, intrinsic tryptophan fluorescence and bilirubin absorbance showed that the guanidine hydrochloride (GdnHCl)-induced unfolding of a multidomain protein, human serum albumin (HSA), followed a two-state process. However, using environment sensitive Nile red fluorescence, the unfolding and folding pathways ofHSA were found to followa three-state process andanintermediatewas detectedinthe range0.25–1.5M GdnHCl.

9p dell39 03-04-2013 39 4   Download

Genistein and daidzein, the major isoflavones present in soybeans, possess a wide spectrum of physiological and pharmacological functions. The bind-ing of genistein to human serum albumin (HSA) has been investigated by equilibrium dialysis, fluorescence measurements, CD and molecular visuali-zation. One mole of genistein is bound per mole of HSA with a binding constant of 1.5 ± 0.2·10 5 m )1 . Binding of genistein to HSA precludes the attachment of daidzein.

17p dell39 27-03-2013 40 4   Download

Human serum albumin (HSA), the most prominent protein in plasma, is best known for its exceptional capacity to bind ligands (e.g. heme and drugs). Here, binding of the anti-HIV drugs abacavir, atazanavir, didano-sine, efavirenz, emtricitabine, lamivudine, nelfinavir, nevirapine, ritonavir, saquinavir, stavudine, and zidovudine to HSA and ferric heme–HSA is reported.

10p dell39 27-03-2013 43 5   Download

Human serum albumin (HSA) exists in both reduced and oxidized forms, and the percentage of oxidized albumin increases in several diseases. How-ever, little is known regarding the pathophysiological significance of oxida-tion due to poor characterization of the precise structural and functional properties of oxidized HSA.

12p inspiron33 25-03-2013 42 4   Download